Patents by Inventor Yukiteru Mimura

Yukiteru Mimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glutathione monoester sulfonate
    Patent number: 5756823
    Abstract: The present invention relates to glutathione monoester sulfonate represented by formula (I): ##STR1## (wherein R.sup.1 represent lower alkyl, and R.sup.2 represents lower alkyl, or substituted or unsubstituted aryl) which readily crystallizes and has high stability, and a simple process for producing the same. According to the process, the product having high purity can be obtained in high yields.
    Type: Grant
    Filed: May 6, 1997
    Date of Patent: May 26, 1998
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Sachiko Kato, Iwao Chujo, Takehiro Ogasa, Masaji Kasai, Yukiteru Mimura
  • Process for producing indolocarbazole derivatives
    Patent number: 5585488
    Abstract: In the formulae, R.sup.1, R.sup.2, and R.sup.3 independently represent lower alkyl or aryl, and R.sup.4 represents lower alkyl.The present invention relates to a process for producing an indolocarbazole derivative represented by Formula (II), comprising the acidic treatment of a silylated indolocarbazole derivative represented by Formula (VI).
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: December 17, 1996
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Masahiko Kinugawa, Yoshiaki Masuda, Yukiteru Mimura, Chikara Murakata, Hiromitsu Saito, Takehiro Ogasa, Masaji Kasai, Shinji Tomioka
  • Process for producing alanylglutamine
    Patent number: 5550283
    Abstract: Disclosed is a process for producing alanylglutamine, which comprises reacting an N-(2-substituted)-propionylglutamine compound represented by the formula (I): ##STR1## where X represents halogen, alkylsulfonyloxy, or substituted or unsubstituted arylsulfonyloxy, with ammonia at a temperature of 60.degree. C. or below.in accordance with the present invention, highly purified alanylglutamine can be produced in a high yield, without racemization.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: August 27, 1996
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Kunimi Inoue, Yoshiyuki Yamada, Kazumi Amatsu, Yukiteru Mimura, Yasunori Nakaguchi, Hiroyuki Shinmura, Yasuyuki Ono, Yutaka Osawa, Shoichi Mizutaki, Masaji Kasai, Shinji Tomioka
  • Process for producing alanylgutamine
    Patent number: 5380934
    Abstract: Disclosed is a process for producing alanylglutamine, which comprises reacting an N-(2-substituted)-propionylglutamine compound represented by the formula (I): ##STR1## where X represents halogen, alkylsulfonyloxy, or substituted or unsubstituted arylsulfonyloxy, with ammonia at a temperature of 60.degree. C. or below.In accordance with the present invention, highly purified alanylglutamine can be produced in a high yield, without racemization.
    Type: Grant
    Filed: October 27, 1993
    Date of Patent: January 10, 1995
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Kunimi Inoue, Yoshiyuki Yamada, Kazumi Amatsu, Yukiteru Mimura, Yasunori Nakaguchi, Hiroyuki Shinmura, Yasuyuki Ono, Yutaka Osawa, Shoichi Mizutaki, Masaji Kasai, Shinji Tomioka
  • Pyrazoloacridone derivatives
    Patent number: 5220026
    Abstract: Disclosed is pyrazoloacridone derivatives represented by formula (I): ##STR1## wherein: each of R.sup.1a, R.sup.1b, R.sup.1c and R.sup.1d independently represents hydrogen, lower alkyl, --(CH.sub.2).sub.p --Xwherein p represents an integer of 1 to 6, and X represents hydroxy, lower alkoxy or --NR.sup.2a R.sup.2bwherein each of R.sup.2a and R.sup.2b independently represents hydrogen, lower alkyl, or --(CH.sub.2).sub.m --Ywherein m represents an integer of 1 to 6, and Y represents hydroxy, lower alkoxy or --NR.sup.3a R.sup.3bwherein each of R.sup.3a and R.sup.3b independently represents hydrogen or lower alkylor --CH[(CH.sub.2).sub.n OH].sub.2wherein n represents an integer of 1 to 5; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 18, 1991
    Date of Patent: June 15, 1993
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yukiteru Mimura, Yasushi Shida, Masaji Kasai, Tadashi Ashizawa, Katsushige Gomi
  • 6H-pyrazolo-[4,5,1-d,e]acridin-6-one derivatives having anit-tumor activity
    Patent number: 5079358
    Abstract: Novel pyrazoloacridone compounds represented by the following formula: ##STR1## and pharmaceutically acceptable salts thereof have an excellent anti-tumor activity.
    Type: Grant
    Filed: June 14, 1989
    Date of Patent: January 7, 1992
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Toru Sugaya, Yukiteru Mimura, Yasushi Shida, Yutaka Osawa, Ikuo Matsukuma, Shiro Akinaga, Makoto Morimoto