Patents by Inventor Yukitoshi Izumi

Yukitoshi Izumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUROSTEROIDS AND ENANTIOMERS THEREOF FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE CONDITIONS
    Publication number: 20240041898
    Abstract: The present disclosure is directed to a composition for prevention or treatment of neurodegenerative conditions. The composition comprises a neurosteroid, a synthetic enantiomer of a neurosteroid, or a combination thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: February 8, 2024
    Inventors: Douglas Covey, Charles Zorumski, Yukitoshi Izumi, Makoto Ishikawa
  • NEUROSTEROIDS AND ENANTIOMERS THEREOF FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE CONDITIONS
    Publication number: 20230058339
    Abstract: The present disclosure is directed to a composition for prevention or treatment of neurodegenerative conditions. The composition comprises a neurosteroid, a synthetic enantiomer of a neurosteroid, or a combination thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: February 23, 2023
    Inventors: Douglas Covey, Charles Zorumski, Yukitoshi Izumi, Makoto Ishikawa
  • Neurosteroids and enantiomers thereof for the prevention and treatment of neurodegenerative conditions
    Patent number: 11497754
    Abstract: The present disclosure is directed to a composition for prevention or treatment of neurodegenerative conditions. The composition comprises a neurosteroid, a synthetic enantiomer of a neurosteroid, or a combination thereof.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: November 15, 2022
    Assignee: Washington University
    Inventors: Douglas Covey, Charles Zorumski, Yukitoshi Izumi, Makoto Ishikawa
  • NEUROSTEROIDS AND ENANTIOMERS THEREOF FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE CONDITIONS
    Publication number: 20200246356
    Abstract: The present disclosure is directed to a composition for prevention or treatment of neurodegenerative conditions. The composition comprises a neurosteroid, a synthetic enantiomer of a neurosteroid, or a combination thereof.
    Type: Application
    Filed: February 5, 2020
    Publication date: August 6, 2020
    Applicant: Washington University
    Inventors: Douglas Covey, Charles Zorumski, Yukitoshi Izumi, Makoto Ishikawa
  • Use of pyruvate to prevent neuronal degeneration associated with ischemia
    Patent number: 5395822
    Abstract: This invention discloses a method of using a salt of pyruvic acid (such as sodium pyruvate) to protect against neuronal degeneration due to ischemia (inadequate blood flow, which can be caused by stroke, cardiac arrest, or other events) or due to hypoxia, hypoglycemia, or cellular disorders which interfere with the energy metabolism of neurons. Treatment with pyruvate can be effective even when administered after the onset of an event that triggers neurodegeneration. A preferred mode of use involves co-administration of a pyruvate salt along with one or more agents that block NMDA and/or non-NMDA receptors, or with insulin or a thrombolytic agent.
    Type: Grant
    Filed: September 20, 1993
    Date of Patent: March 7, 1995
    Inventors: Yukitoshi Izumi, John W. Olney