Abstract: A PFO closing device includes a suction and hold portion at a distal portion of a catheter for sucking and holding biological tissue of a foramen ovale valve and an atrial septum secundum from one side, an electrode portion on the side contacting the biological tissue; a negative pressure supply unit for applying negative pressure to the suctional portion and hold portion, a hold mechanism adapted to protrude from the distal tip of the catheter, and be inserted into the foramen ovale to hold the foramen ovale valve while pressing it from the other side and an energy supply unit for supplying energy to the electrode portion. Energy is supplied from the energy supply unit to the electrode portion, and the foramen ovale valve and the atrial septum secundum are mutually fused together.

Abstract: A biological tissue closing device includes a clamper comprising a stick portion provided at a distal portion of a catheter for sticking to a biological tissue, and a sandwich member for sandwiching the biological tissue in cooperation with the stick portion, and an electric energy supply unit for supplying electric energy to the clamper. The biological tissue is fused by making the stick portion and the sandwich member of the clamper be electrode members, by sandwiching the biological tissue with the damper and by supplying electric energy from the electric energy supply unit, wherein the damper is configured so that each of the stick portion and the sandwich member are movable independently with respect to the catheter.

Abstract: A PFO closing device for bringing the septum primum and the septum secundum into contact with each other and joining them together includes a clamping mechanism and energy supplying device. The clamping mechanism includes a needle part for puncturing the septum primum, and a clamping member for cooperating with the needle part in clamping therebetween tissue of the septum primum and the septum secundum. The energy supplying device supplies energy for joining the tissues clamped by the needle part and the clamping member. The clamping mechanism is mounted in a catheter so as to be protrudable from and retractable into the catheter.

Abstract: Photocurable resin composition for photofabrication of three-dimensional objects comprising (A) 5-80 parts by weight of an oxetane compound, (B) 5-80 parts by weight of an epoxy compound, (C) 0, 1 10 parts by weight of a photoacid generator, (D) 1-35 parts by weight of elastomer particles with an average particle diameter of 10-700 nm, (E) 0-35 parts by weight of a polyol compound, (F) 0-45 parts by weight of an ethylenically unsaturated monomer, and (G) 0-10 parts by weight of a radical photopolymerization initiator.

Abstract: A device for treating a patent foramen ovale has a first part having a predetermined length; a second part having a predetermined length; a third part having a predetermined length; and a pulling member which penetrates into the second part from a side face of a distal portion of the second part, crosses the second cylindrical part obliquely and extends from a side face of a proximal portion of the second part and penetrates into the third part from a side face of a distal portion of the third part, with one end of the pulling member held by a proximal portion of the first part. A part of a locking mechanism provided at other end of the pulling member and a part of the locking mechanism provided at the third part are locked to each other, when the pulling member is pulled to allow the first part and the second part proximate to each other and the second part and the third part to be proximate to each other.

Abstract: A blood vessel extroverting instrument used to turn an end of a blood vessel inside out. The instrument has a contact portion to be brought into contact with an end of a blood vessel, a supporting portion on which the contact portion is supported, and an operating mechanism for increasing and reducing the diameter of the contact portion. At least two portions of the end of the blood vessel in the radial direction can be simultaneously expanded and/or reversed by operating the operating mechanism. Therefore the blood vessel extroverting instrument provided by the present invention is capable of easily turning an end of a blood vessel inside out in a short time without damaging the blood vessel.

Abstract: Photocurable resin composition for photofabrication of three-dimensional objects comprising (A) 5-80 parts by weight of an exetane compound, (B) 5-80 parts by weight of an epoxy compound, (C) 0.1 10 parts by weight of a photoacid generator, (D) 1-35 parts by weight of elastomer particles with an average particle diameter of 10-700 nm, (E) 0-35 parts by weight of a polyol compound, (F) 0-45 parts by weight of an ethylenically unsaturated monomer, end (G) 0-10 parts by weight of a radical photopolymerization initiator.

Abstract: A blood vessel anastomosing appliance includes a pair of rings to be inserted in two blood vessels, respectively, inside incisions formed in the blood vessels, and threads spanningly laid between the rings to connect them to each other. The blood vessel anastomosing appliance is so configured that, by pulling the threads in the exterior of the blood vessels, the rings are drawn closer to each other, and edge portions of the incisions in the two blood vessels are clamped between the rings. The blood vessel anastomosing appliance further includes fastening members. The fastening members function as a holding unit for holding the condition where the rings have been drawn close to each other, by fastening outer circumferential portions of the rings through the medium of vessel walls of the blood vessels.

Abstract: A method of end-to-side anastomosis of blood vessels for connecting a side portion of a first blood vessel to an end portion of a second blood vessel involves holding a first site on the side portion of the first blood vessel using a holder, and partially elevating the side portion of the first blood vessel; superimposing a second site on the side portion of the first blood vessel on the end of the second blood vessel and fixing them with a ring-shaped fixing member to each other; and detaching the holder from the first blood vessel when they are fixed by the fixing member or after they are fixed. The end-to-side blood vessel anastomosis method can readily open the dissected portion on the side of the blood vessel upon end-to-side blood vessel anastomosis and retain it in that state. No foreign matter is present within the blood vessel after completion of the anastomosis.

Abstract: Photocurable resin composition for photofabrication of three-dimensional objects comprising

Abstract: A blood vessel extroverting instrument used to turn an end of a blood vessel inside out. The instrument has a contact portion to be brought into contact with an end of a blood vessel, a supporting portion on which the contact portion is supported, and an operating mechanism for increasing and reducing the diameter of the contact portion. At least two portions of the end of the blood vessel in the radial direction can be simultaneously expanded and/or reversed by operating the operating mechanism. Therefore the blood vessel extroverting instrument provided by the present invention is capable of easily turning an end of a blood vessel inside out in a short time without damaging the blood vessel.

Abstract: The method of end-to-side anastomosis of blood vessels by connecting a side portion of a first blood vessel to an end portion of a second blood vessel, comprises the steps of holding a first site on the side portion of the first blood vessel located in the vicinity of an peripheral portion of an opening formed on the side portion of the first blood vessel using a holder, and partially elevating the side portion of the first blood vessel; superimposing a second site on the side portion of the first blood vessel that is more distant from the peripheral portion of the opening formed on the side portion of the blood vessel than the first site is and the end of the second blood vessel and fixing them with a ring-shaped fixing member to each other; and detaching the holder from the first blood vessel when they are fixed by the fixing member or after they are fixed.

Abstract: A method of coating a resin mold is provided. The method can produce a resin mold with excellent releasability and durability, even if the molded resin material comprises a functional group that is reactive with the functional group remaining near the molding surface of the resin mold.

Abstract: A delivery blood storing member-equipped blood reservoir tank has a blood reservoir tank portion, and a delivery blood storing member that communicates with a blood outlet formed in the blood reservoir tank portion. The delivery blood storing member allows blood to flow out of an interior thereof when pressed from outside. The delivery blood storing member reserves amounts of blood in accordance with the height of liquid surface in the blood reservoir tank portion if the amount of blood in the blood reservoir tank portion becomes equal to or less than a predetermined value. The delivery blood storing member includes a body part that is formed from a hard material, and a flexible diaphragm whose peripheral end is fixed to the delivery blood storing member body part. The diaphragm produces substantially no self-restoring force against deformation.