Abstract: Disclosed is a method for producing a fusion protein of human serum albumin and human growth hormone. The method comprises (a) a step of culturing a mammalian cell capable of producing the protein in a serum-free medium and causing the protein to be secreted into the culture fluid, (b) a step of collecting a culture supernatant by removing the mammalian cell from the culture fluid, and (c) a step of purifying the protein from the culture supernatant by using column chromatography using a material to which an antibody having an affinity for the protein is bound as a stationary phase, column chromatography using a material having an affinity for phosphate group as a stationary phase, cation exchange column chromatography, and size exclusion column chromatography.

Abstract: In a solution cultivation method for a low potassium vegetable, an entire cultivation period from seeding to harvesting is divided into a first cultivation period and a second cultivation period depending on the vegetable to be cultivated. In the first cultivation period, the vegetable is cultivated in a first culture solution containing a first fertilizer for solution cultivation which contains potassium. In the second cultivation period, the vegetable is cultivated in a second culture solution containing a second fertilizer for solution cultivation which does not substantially contain potassium. During the second cultivation period, an air flow is applied at a controlled speed to the growing point of the vegetable.

Abstract: The purpose of the present invention is to provide a specific composition for promoting expression of aquaporin 3, and use thereof. The present invention relates to a composition for promoting expression of aquaporin 3, the composition including a galloyl group-containing flavan-3-ol monomer and/or a galloyl group-containing flavan-3-ol polymer as an active ingredient.

Abstract: An illumination apparatus includes first and second light sources arranged substantially linearly; and a light guide member having first and second light receiving portions, and a light emitting portion. The light receiving portions are configured to refract light from the first and second light sources toward the light emitting portion; and the light emitting portion is configured to refract light from the light receiving portions toward a space between the first and second light sources.

Abstract: A plant cultivation apparatus includes an illuminator, and a light guide member. The illuminator includes a first light source and a second light source which are arranged in series. The light guide member includes a first light receiver, a light emitter, and a second light receiver, and is disposed to cover at least a portion of a non-light emitting portion between the first light source and the second light source. The first light receiver refracts a first light from the first light source to output the first light toward the light emitter. The second light receiver refracts a second light from the second light source to output the second light toward the light emitter. The light emitter refracts the first light and the second light to irradiate a plant cultivation space with the first light and the second light.

Abstract: An object of the present invention is to provide hyaluronidase inhibitors, collagenase inhibitors, elastase inhibitors, MMP-1 production suppressors, and collagen synthesis promoters that contain as an active component one or more pigment compounds that are obtained as extracted from plants of the family Rosaceae, as well as agents for cutaneous application, skin cosmetics, and quasi-drugs that contain such pigment compounds. The present invention provides hyaluronidase inhibitors, collagenase inhibitors, elastase inhibitors, MMP-1 production suppressors, collagen synthesis promoters, agents for cutaneous application, skin cosmetics, and quasi-drugs that contain one or more compounds in a class of rosacyanins or one or more compounds in a class of rosadelphins as an active component.

Abstract: In an air conditioning apparatus, mixed ambient gas obtained by mixing carbon dioxide with ambient gas in a mixing unit communicating with outlets is supplied to a plant substantially uniformly through the outlets installed in the vicinity of the plant, which makes transpiration of leaves of the plant uniform, and further allows air conditioning control to be performed only over the vicinity of the plant and carbon gas concentration to be managed on the vicinity of the plant.

Abstract: In a solution cultivation method for a low potassium vegetable, an entire cultivation period from seeding to harvesting is divided into a first cultivation period and a second cultivation period depending on the vegetable to be cultivated. In the first cultivation period, the vegetable is cultivated in a first culture solution containing a first fertilizer for solution cultivation which contains potassium. In the second cultivation period, the vegetable is cultivated in a second culture solution containing a second fertilizer for solution cultivation which does not substantially contain potassium. During the second cultivation period, an air flow is applied at a controlled speed to the growing point of the vegetable.

Abstract: An object of the present invention is to provide hyaluronidase inhibitors, collagenase inhibitors, elastase inhibitors, MMP-1 production suppressors, and collagen synthesis promoters that contain as an active component one or more pigment compounds that are obtained as extracted from plants of the family Rosaceae, as well as agents for cutaneous application, skin cosmetics, and quasi-drugs that contain such pigment compounds. The present invention provides hyaluronidase inhibitors, collagenase inhibitors, elastase inhibitors, MMP-1 production suppressors, collagen synthesis promoters, agents for cutaneous application, skin cosmetics, and quasi-drugs that contain one or more compounds in a class of rosacyanins or one or more compounds in a class of rosadelphins as an active component.

Abstract: In an air conditioning apparatus, mixed ambient gas obtained by mixing carbon dioxide with ambient gas in a mixing unit communicating with outlets and, moreover, adjusting temperature and humidity of the mixed ambient gas is supplied to a plant substantially uniformly through the outlets installed in the vicinity of the plant, which makes transpiration of leaves of the plant uniform, and further allows air conditioning control to be performed only over the vicinity of the plant and carbon gas concentration to be managed on the same.

Abstract: Providing a compound capable of continuously taking and having a vascular endothelial function improving effect by enhancing NO function from the vascular endothelial cells. A compound represented by Formula (I) wherein R1, R2, R3 and R4 are each independently H or a gallate group, a vascular endothelial function improving agent, food and drink or pharmaceutical composition containing the compound.

Abstract: Provided is a highly palatable and safe glucosyltransferase inhibitor or anti-dental caries agent. A glucosyltransferase inhibitor or anti-dental caries agent having an epigallocatechin gallate polymer or a salt thereof. Particularly, the above agent containing an epigallocatechin gallate polymer, which is a compound in which chroman rings are bonded at position 6 and/or 8 via a methylene group.

Abstract: The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages. According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

Abstract: Disclosed is a novel compound contained in blue rose. This novel compound, which is contained in blue rose, has a chemical structure represented by general formula (I): [wherein R1 is a group as set forth in claim 1; and R2 represents —OH, or R1 and R2 together form —O—]. Also disclosed are a rose plant containing the aforesaid compound, and a part of the same.

Abstract: The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages. According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

Abstract: Foods and beverages, quasi-drugs, and pharmaceuticals that exhibit high antioxidative activity in the living body for a long time are provided. High antioxidative activity can be imparted by incorporating desrhamnosyl acteoside in an olive extract. A desrhamnosyl acteoside-containing composition can be prepared by treating an acteoside-containing composition with glycosidase.

Abstract: Providing a compound capable of continuously taking and having a vascular endothelial function improving effect by enhancing NO function from the vascular endothelial cells. A compound represented by Formula (I) wherein R1, R2, R3 and R4 are each independently H or a gallate group, a vascular endothelial function improving agent, food and drink or pharmaceutical composition containing the compound.

Abstract: Providing a compound capable of continuously taking and having a vascular endothelial function improving effect by enhancing NO function from the vascular endothelial cells. A compound represented by Formula (I) wherein R1, R2, R3 and R4 are each independently H or a gallate group, a vascular endothelial function improving agent, food and drink or pharmaceutical composition containing the compound.

Abstract: The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages. According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

Abstract: The present invention provides lipase inhibitors containing dimers of flavan-3-ols derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the present invention provides lipase inhibitors containing at least one of assamicains represented by the formula: wherein G represents a galloyl group; theasinensins represented by the formula: wherein R1 represents G or H, and R2 represents G; and theaflavins represented by the formula: wherein R1 and R2 independently represent G or H; as well as foods and beverages and medicines containing said lipase inhibitors.