Abstract: The object of the invention is to find a simple biomarker with high reproducibility with regard to a method for evaluating the activity of the condition and progression of rheumatoid arthritis disease and provide an effective evaluation method therefor. The invention is to provide a method for determining the value of a rheumatoid arthritis-linked indicator in a subject, the method being characterized by comprising a step for measuring the amount of expression of the FAM20A gene in blood collected from the subject, a step for analyzing the measured amount of expression using a gene expression profile that is prepared in advance and correlates with the indicator and a step for estimating the value of the indicator in the subject on the basis of the analysis results.

Abstract: An optical connector adapter has an optical connection sleeve having a first end portion and a second end portion opposite the first end portion. A sleeve holder has a first cylindrical member having a first through-hole receiving the first end portion of the optical connection sleeve. The sleeve holder is disposed in a tubular housing which has a second cylindrical member having a second through-hole receiving the second end portion of the optical connection sleeve. Engagement members engage the sleeve holder and the housing together in a state that a first end of the first cylindrical member and a first end of the second cylindrical member are abutted against each other. Engagement convex portions project radially inward at respective second ends of the first cylindrical member and the second cylindrical member for regulating movement of the optical connection sleeve in an axial direction.