Patents by Inventor Yuko NAKAGAMI

Yuko NAKAGAMI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11045471
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: June 29, 2021
    Assignee: SHOWA DENKO K.K.
    Inventors: Daisuke Yagyu, Yuko Nakagami, Ryota Niibayashi, Eiko Kato
  • Patent number: 10918585
    Abstract: Provided is an anti-aging agent for skin which contains, as an active component, an inositol derivative in which a monosaccharide or an oligosaccharide is bonded to inositol, in which a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 16, 2021
    Assignee: SHOWA DENKO K.K.
    Inventors: Yuko Nakagami, Shinji Yamaki, Ichiro Fujita, Tadashi Yoneda
  • Publication number: 20200268780
    Abstract: A mixture of inositol derivatives in which a sugar is bonded to inositol includes an inositol derivative (A10) in which total sugars bonded to one inositol molecule is 10 or more in terms of monosaccharide units. In addition, a mixture of inositol derivatives in which a sugar is bonded to inositol includes 5% by mass or more of an inositol derivative (A7), in which total sugars bonded to one inositol molecule is 7 or more in terms of monosaccharide units, with respect to a total amount of inositol derivatives (100% by mass).
    Type: Application
    Filed: September 4, 2018
    Publication date: August 27, 2020
    Applicant: SHOWA DENKO K.K.
    Inventors: Ichiro FUJITA, Shinji YAMAKI, Yuko NAKAGAMI
  • Publication number: 20200215069
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 9, 2020
    Applicant: SHOWA DENKO K.K.
    Inventors: Daisuke YAGYU, Yuko NAKAGAMI, Ryota NIIBAYASHI, Eiko KATO
  • Patent number: 10646487
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring].
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 12, 2020
    Assignee: SHOWA DENKO K.K.
    Inventors: Daisuke Yagyu, Yuko Nakagami, Ryota Niibayashi, Eiko Kato
  • Publication number: 20190224199
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Application
    Filed: June 8, 2017
    Publication date: July 25, 2019
    Applicant: SHOWA DENKO K.K.
    Inventors: Daisuke YAGYU, Yuko NAKAGAMI, Ryota NIIBAYASHI, Eiko KATO
  • Publication number: 20180360719
    Abstract: Provided is an anti-aging agent for skin which contains, as an active component, an inositol derivative in which a monosaccharide or an oligosaccharide is bonded to inositol, in which a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 20, 2018
    Applicant: SHOWA DENKO K.K.
    Inventors: Yuko NAKAGAMI, Shinji YAMAKI, Ichiro FUJITA, Tadashi YONEDA