Patents by Inventor Yuko Oda

Yuko Oda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130174285
    Abstract: The present invention prepared a non-human animal in which Fgf18 gene was knocked out in a keratin-5 positive cell-specific manner using a Cre-loxP system; it provides a non-human model animal in which FGF18 expression has been inhibited in a hair follicle-specific manner to shorten the telogen phase of hair growth cycle. The non-human model animal is useful in studying hair follicles and skin, particularly hair growth occurring cyclically in hair follicle cells, and is applicable to the development of and screening for novel drugs against hair follicle or skin disorders.
    Type: Application
    Filed: September 16, 2011
    Publication date: July 4, 2013
    Inventors: Toru Imamura, Miho Ueki, Yuko Oda
  • Publication number: 20120251455
    Abstract: A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract).
    Type: Application
    Filed: January 27, 2012
    Publication date: October 4, 2012
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Toru IMAMURA, Miho KIMURA, Mitsuko KAWANO, Nozomi TSUJINO, Akiko KURAMOCHI, Yuko ODA, Kaori MOTOMURA, Masashi SUZUKI, Masahiro ASADA, Azusa KAMEYAMA, Sumie TOGAYACHI, Syuichi OKA
  • Publication number: 20100203055
    Abstract: It is intended to provide a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia by determining an endogenous factor that inhibits hair growth and screening for substances that inhibit the activity or expression of the endogenous factor. It has been found that FGF18 inhibits hair growth. A method of screening for substances that inhibit the activity of FGF18 or substances that inhibit the expression of FGF18 to thereby obtain candidates for the hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia is disclosed. Also disclosed is a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia comprising, as an active ingredient(s), a substance that inhibit the activity of FGF18 and/or a substance that inhibits the expression of FGF18 such as a partial peptide of FGF18 or a Momordica charantia hot water extract.
    Type: Application
    Filed: February 19, 2008
    Publication date: August 12, 2010
    Inventors: Toru Imamura, Miho Kimura, Mitsuko Kawano, Nozomi Tsujino, Akiko Kuramochi, Yuko Oda, Kaori Motomura, Masashi Suzuki, Masahiro Asada, Azusa Kameyama, Sumie Togayachi, Syuichi Oka
  • Publication number: 20100183733
    Abstract: A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract).
    Type: Application
    Filed: February 19, 2008
    Publication date: July 22, 2010
    Inventors: Toru Imamura, Miho Kimura, Mitsuko Kawano, Nazomi Tsujino, Akiko Kuramochi, Yuko Oda, Kaori Motomura, Masashi Suzuki, Masahiro Asada, Azusa Kameyama, Sumie Togayachi, Syuichi Oka
  • Patent number: 7282481
    Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method of functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: October 16, 2007
    Assignee: Director-General of Agency of Industrial Science and Technology
    Inventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima
  • Publication number: 20060079451
    Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method of functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.
    Type: Application
    Filed: November 23, 2005
    Publication date: April 13, 2006
    Applicant: Director-General of Agency of Industrial Science and Technology
    Inventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima
  • Patent number: 7005415
    Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method for functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: February 28, 2006
    Assignee: Director-General Agency of Industrial Science and Technology
    Inventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima