Patents by Inventor Yuko Okada
Yuko Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240277861Abstract: An anti-HBV agent according to the present invention contains as an active ingredient a substance that binds to LIPG and inhibits the function(s) of LIPG. The inventors of the present application have found that LIPG is a factor playing an important role in HBV attachment and uptake, and functions as a cofactor that supports HBV entry into cells independently of NTCP, and also contributes to HBV proliferation in cells. T The LIPG-binding substance binds to LIPG on the surface of liver cells to inhibit HBV attachment and uptake into cells and, when delivered into liver cells, binds to intracellular LIPG to block any step(s) in the intracellular HBV proliferation process, thereby exerting an anti-HBV activity.Type: ApplicationFiled: July 22, 2022Publication date: August 22, 2024Applicant: PUROTECH BIO, INC.Inventors: Hiroshi YANAGAWA, Noriko TABATA, Yuko YONEMURA, Mayuko IDE, Satoru ITO, Shuichi KANEKO, Masao HONDA, Takayoshi SHIRASAKI, Kazuhisa MURAI, Hikari OKADA
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Publication number: 20240228573Abstract: Disclosed is a method for producing a fusion protein of human serum albumin and human growth hormone. The method comprises (a) a step of culturing a mammalian cell capable of producing the protein in a serum-free medium and causing the protein to be secreted into the culture fluid, (b) a step of collecting a culture supernatant by removing the mammalian cell from the culture fluid, and (c) a step of purifying the protein from the culture supernatant by using column chromatography using a material to which an antibody having an affinity for the protein is bound as a stationary phase, column chromatography using a material having an affinity for phosphate group as a stationary phase, cation exchange column chromatography, and size exclusion column chromatography.Type: ApplicationFiled: October 16, 2020Publication date: July 11, 2024Applicant: JCR PHARMACEUTICALS CO., LTD.Inventors: Shinji KAKIMOTO, Tsuyoshi FUKUI, Yukichi HATANO, Ayaka KOTANI, Ryota KATSUNO, Yuko OKADA
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Publication number: 20240132566Abstract: Disclosed is a method for producing a fusion protein of human serum albumin and human growth hormone. The method comprises (a) a step of culturing a mammalian cell capable of producing the protein in a serum-free medium and causing the protein to be secreted into the culture fluid, (b) a step of collecting a culture supernatant by removing the mammalian cell from the culture fluid, and (c) a step of purifying the protein from the culture supernatant by using column chromatography using a material to which an antibody having an affinity for the protein is bound as a stationary phase, column chromatography using a material having an affinity for phosphate group as a stationary phase, cation exchange column chromatography, and size exclusion column chromatography.Type: ApplicationFiled: October 15, 2020Publication date: April 25, 2024Applicant: JCR PHARMACEUTICALS CO., LTD.Inventors: Shinji KAKIMOTO, Tsuyoshi FUKUI, Yukichi HATANO, Ayaka KOTANI, Ryota KATSUNO, Yuko OKADA
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Patent number: 11938346Abstract: A particle beam therapy apparatus has a position and posture setter that moves a movable body, that is at least one of the irradiation nozzle and the treatment table. A movement path of the movable body is determined when adapting the positional posture of the movable body from one condition among a plurality of prescribed conditions to another condition. An evaluation value is obtained for adapting the positional posture of the movable body to each of a plurality of prescribed conditions. This evaluation value is for a case of moving the movable body according to the movement path. A setting order is determined for adapting the positional posture of the movable body to each prescribed condition based on the evaluation value; and the positional posture of the movable body is adapted to each of the plurality of prescribed conditions by moving the movable body according to the determined movement path.Type: GrantFiled: October 16, 2019Date of Patent: March 26, 2024Assignee: HITACHI, LTD.Inventors: Hiroki Takahashi, Masanori Suzuki, Takuto Yagihashi, Takeshi Fujita, Isao Furuse, Yuko Okada
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Patent number: 11342211Abstract: The present disclosure provides a wafer inspection technology that involves less degradation of the image quality even when an object to be observed has a variation in height due to warpage, etc. of a wafer. This wafer inspection apparatus obtains an image with less degradation by: adjusting the focal point of an observation optical system to a height measured by a height sensor for measuring wafer surface heights; and further, correcting a switching signal for a CCD line sensor on the basis of stage position data and optical magnification data corresponding to the height so as to make a correction corresponding to the wafer surface height.Type: GrantFiled: May 30, 2018Date of Patent: May 24, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Akira Doi, Minoru Sasaki, Masaki Hasegawa, Hironori Ogawa, Tomohiko Ogata, Yuko Okada
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Publication number: 20220042571Abstract: A vibration damping member mounted to an inside of a housing of an acoustic device includes a first member, a second member, and a third member. The first member and the second member are connected through the third member. The third member has a lower elastic modulus than the first member and the second member.Type: ApplicationFiled: October 25, 2021Publication date: February 10, 2022Inventors: Akira Miki, Yuko Okada, Koichi Morita
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Publication number: 20210379402Abstract: A particle beam therapy apparatus has a position and posture setter that moves a movable body, that is at least one of the irradiation nozzle and the treatment table. A movement path of the movable body is determined when adapting the positional posture of the movable body from one condition among a plurality of prescribed conditions to another condition. An evaluation value is obtained for adapting the positional posture of the movable body to each of a plurality of prescribed conditions. This evaluation value is for a case of moving the movable body according to the movement path. A setting order is determined for adapting the positional posture of the movable body to each prescribed condition based on the evaluation value; and the positional posture of the movable body is adapted to each of the plurality of prescribed conditions by moving the movable body according to the determined movement path.Type: ApplicationFiled: October 16, 2019Publication date: December 9, 2021Inventors: Hiroki TAKAHASHI, Masanori SUZUKI, Takuto YAGIHASHI, Takeshi FUJITA, Isao FURUSE, Yuko OKADA
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Publication number: 20210118710Abstract: The present disclosure provides a wafer inspection technology that involves less degradation of the image quality even when an object to be observed has a variation in height due to warpage, etc. of a wafer. This wafer inspection apparatus obtains an image with less degradation by: adjusting the focal point of an observation optical system to a height measured by a height sensor for measuring wafer surface heights; and further, correcting a switching signal for a CCD line sensor on the basis of stage position data and optical magnification data corresponding to the height so as to make a correction corresponding to the wafer surface height.Type: ApplicationFiled: May 30, 2018Publication date: April 22, 2021Inventors: Akira DOI, Minoru SASAKI, Masaki HASEGAWA, Hironori OGAWA, Tomohiko OGATA, Yuko OKADA
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Patent number: 8912363Abstract: Provided is a chlorinated polyether which has excellent solubility in solvents and excellent thermal stability, has the excellent effect of improving the adhesion of coating materials, inks, and adhesives to polyolefins, can be expected to be usable as a flame retardant, and is useful also as a novel starting material for polyurethanes. The polyether is a novel chlorinated polyether containing, as a repeating unit, at least one of the chlorinated-ether residue represented by the following formula (1) and the chlorinated-ether residue represented by the following formula (2). Also provided is a novel polyurethane obtained therefrom.Type: GrantFiled: June 9, 2009Date of Patent: December 16, 2014Assignee: Tosoh CorporationInventors: Megumi Okada, Mayuko Okada, Yuko Okada
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Publication number: 20110124761Abstract: Provided is a chlorinated polyether which has excellent solubility in solvents and excellent thermal stability, has the excellent effect of improving the adhesion of coating materials, inks, and adhesives to polyolefins, can be expected to be usable as a flame retardant, and is useful also as a novel starting material for polyurethanes. The polyether is a novel chlorinated polyether containing, as a repeating unit, at least one of the chlorinated-ether residue represented by the following formula (1) and the chlorinated-ether residue represented by the following formula (2). Also provided is a novel polyurethane obtained therefrom.Type: ApplicationFiled: June 9, 2009Publication date: May 26, 2011Inventors: Takashi Okada, Megumi Okada, Mayuko Okada, Yuko Okada
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Patent number: 7161285Abstract: A fabrication method for an emitter includes the steps of forming on a glass substrate a CNT film which contains a plurality of carbon nanotubes (CNTs) and constitutes an emitter electrode, forming a gate electrode via an insulating film on the CNT film, forming a plurality of gate openings in the gate electrode and the insulating film, and aligning upright the CNTs in the gate opening. The upright alignment generates a stable uniform emission current and provides excellent emission characteristics.Type: GrantFiled: November 19, 2001Date of Patent: January 9, 2007Assignee: NEC CorporationInventors: Akihiko Okamoto, Kazuo Konuma, Yoshinori Tomihari, Fuminori Ito, Yuko Okada
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Publication number: 20040104660Abstract: A fabrication method for an emitter includes the steps of forming on a glass substrate (10) a CNT film (12) which contains a plurality of carbon nanotubes (CNTs) (12a) and constitutes an emitter electrode (12b), forming a gate electrode (16) via an insulating film (13) on the CNT film (12), forming a plurality of gate openings (17) in the gate electrode (16) and the insulating film (13), and aligning upright the CNTs (12a) in the gate opening (17). The upright alignment generates a stable uniform emission current and provides excellent emission characteristics.Type: ApplicationFiled: December 22, 2003Publication date: June 3, 2004Inventors: Akihiko Okamoto, Kazuo Konuma, Yoshinori Tomihari, Fuminori Ito, Yuko Okada
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Publication number: 20040043219Abstract: Upon wet etching and thereby patterning carbon nanotubes (106) by a transfer method, a solution for dissolving a binder used in the transfer method as a solution used for the wet etching is used, and the carbon nanotubes (106) tangled with each other are rubbed off with a cloth-like substance (112) upon the wet etching. Furthermore, upon patterning the carbon nanotubes (106) using a dry etching method, a metal film or a film made of a substance resistant to damage upon the dry etching and causing no damage to the carbon nanotubes (106) when removed is used as a mask. A fine carbon nanotube pattern having an excellent flatness is formed.Type: ApplicationFiled: May 29, 2003Publication date: March 4, 2004Inventors: Fuminori Ito, Yuko Okada, Yoshinori Tomihari, Kazuo Konuma, Akihiko Okamoto
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Publication number: 20040036401Abstract: To provide a method for manufacturing a high-performance field electron emission apparatus, wherein occurrence of damage to a CNT during a manufacturing step is prevented, and thereby, the CNT can adequately keep an inherent electron emission characteristic of exhibiting a large current density with a low threshold value. This method for manufacturing a field electron emission apparatus is related to the manufacture of a field electron emission apparatus using the CNT as an electron source. In the method, a protective film formation step is performed in order to form an aluminum film 4 as the protective film on the surface of the CNT film 2 during a manufacturing process of at least a part of the apparatus. The CNT surface structure is protected with this conductive protective film (aluminum film 4, 40), while the structure significantly affects the electron emission characteristic. Consequently, the electron emission characteristic inherent in the CNT can be adequately ensured and be exhibited.Type: ApplicationFiled: August 8, 2003Publication date: February 26, 2004Inventors: Kazuo Konuma, Yoshinori Tomihari, Yuko Okada
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Electric discharge processing method for an electron tube using a field emission cold cathode device
Patent number: 6380700Abstract: The present invention provides a method of carrying out an electric discharge processing to an electron tube having a field emission cold cathode device, wherein at least a high voltage electrode of the electron tube is maintained in a high voltage range, whilst all electrodes of the electron tube except for the at least high voltage electrode are maintained in a lower voltage range than the high voltage range.Type: GrantFiled: April 6, 2000Date of Patent: April 30, 2002Assignee: NEC CorporationInventor: Yuko Okada -
Patent number: 5584133Abstract: A baseball ball catching implement has a name plate fitting of rubber or synthetic resin having elasticity affixed to a back member of the implement at any desired position. The implement includes a name plate removably fitted in the name plate fitting. The name plate fitting includes a frame member having a contour corresponding to that of a name plate. The frame member includes an annular inward ledge arranged to define an annular step for receiving and retaining the name plate at its periphery, an annular outward ledge at the top of the frame member and an annular base portion extending outwardly from the lower end of the frame member beyond the ledge. The ledge and the base portion define an outwardly opening annular recess therebetween arranged to receive an edge defining a hole in the back member of the baseball ball catching implement. The annular base portion and the back member are connected to each other by stitches or in any other suitable way.Type: GrantFiled: March 21, 1995Date of Patent: December 17, 1996Assignee: Mizuno CorporationInventors: Ken Motooka, Yuko Okada, Junichi Dogan, Masaki Terashita
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Patent number: 5119189Abstract: A stereoscopic imaging system enabling observation of a stereoscopic image due to parallax by reproducing, on a single screen in an image-reproducing means two kinds of images of an object which are taken by two imaging units and between which there is parallax and by observing the images in such a manner that the left and right eyes of the observer observe only the separate images taken by the separate imaging units corresponding to the left and right eyes, wherein there is provided swing means for mechanically or electronically shifting the optical axes of the respective lenses of said two imaging units, by which swing means the observer can view a stereoscopic image without fatigue and in a natural condition.Type: GrantFiled: October 24, 1990Date of Patent: June 2, 1992Assignee: Hitachi, Ltd.Inventors: Taro Iwamoto, Kichio Nakajima, Hiroshi Yamamoto, Yuko Okada, Yukio Sumiya