Patents by Inventor Yuko Yamakoshi

Yuko Yamakoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolo[1,5-a]pyrimidine derivatives
    Patent number: 7667036
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: February 23, 2010
    Assignee: Teijin Pharma Limited
    Inventors: Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Kenichiro Kataoka, Dale Robert Mitchell, Donald James Simpson, Clifford John Harris, Joelle Le, Yuko Yamakoshi
  • Pyrazolo[1,5-A] pyrimidine derivatives
    Patent number: 7557110
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: July 7, 2009
    Assignee: Teijin Pharma Limited
    Inventors: Kenichiro Kataoka, Naotaka Suzuki, Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Aiko Fujino, Yasuhiro Oue, Yuko Yamakoshi, Satoshi Sugiura, Robert Dale Mitchell, James Donald Simpson, John Clifford Harris, Joelle Le
  • Pyrazolopyrimidine Derivatives or Pharmaceutically Acceptable Salts Thereof
    Publication number: 20090054472
    Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.
    Type: Application
    Filed: September 29, 2008
    Publication date: February 26, 2009
    Applicant: TEIJIN PHARMA LIMITED
    Inventors: Gen UNOKI, Tomomi KOSUGI, Mika TAKAKUWA, Hiroaki MAKINO, Kenichiro KATAOKA, Yuko YAMAKOSHI
  • Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof
    Patent number: 7473694
    Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: January 6, 2009
    Assignee: Teijin Pharma Limited
    Inventors: Gen Unoki, Tomomi Kosugi, Mika Takakuwa, Hiroaki Makino, Kenichiro Kataoka, Yuko Yamakoshi
  • Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof
    Patent number: 7417053
    Abstract: A pyrazolo[1,5-a]pyridine derivative represented by formula (I) and salt thereof exhibit excellent MAPKAP-K2 inhibitory activity. Accordingly, medicines comprising this compound as an active ingredient are expected to be valuable for treating or preventing diseases mediated by MAPKAP-K2 such as inflammatory injury, autoimmune diseases, asteropathia destruens, cancer and/or growth of tumor.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: August 26, 2008
    Assignee: Teijin Pharma Limited
    Inventors: Gen Unoki, Yoshiyuki Matsumoto, Yohei Matsueda, Tomomi Kosugi, Mika Takakuwa, Hiroaki Makino, Kenichiro Kataoka, Yuko Yamakoshi, Motoko Hamada
  • Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof
    Publication number: 20070173519
    Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.
    Type: Application
    Filed: March 17, 2006
    Publication date: July 26, 2007
    Inventors: Gen Unoki, Tomomi Kosugi, Mika Takakuwa, Hiroaki Makino, Kenichiro Kataoka, Yuko Yamakoshi
  • Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof
    Publication number: 20070072898
    Abstract: A pyrazolo[1,5-a]pyridine derivative represented by formula (I) and salt thereof exhibit excellent MAPKAP-K2 inhibitory activity. Accordingly, medicines comprising this compound as an active ingredient are expected to be valuable for treating or preventing diseases mediated by MAPKAP-K2 such as inflammatory injury, autoimmune diseases, asteropathia destruens, cancer and/or growth of tumor.
    Type: Application
    Filed: April 7, 2006
    Publication date: March 29, 2007
    Inventors: Gen Unoki, Yoshiyuki Matsumoto, Yohei Matsueda, Tomomi Kosugi, Mika Takakuwa, Hiroaki Makino, Kenichiro Kataoka, Yuko Yamakoshi, Motoko Hamada
  • Protein kinase inhibitors
    Publication number: 20060205743
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Application
    Filed: March 11, 2004
    Publication date: September 14, 2006
    Inventors: Kenichiro Kataoka, Tomomi Kosugi, Minoru Imai, Dale Mitchell, Donald Simpson, Naotaka Suzuki, Yuko Yamakoshi
  • Pyrazolo[1,5-A] pyrimidine derivatives
    Publication number: 20060189632
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Application
    Filed: March 1, 2004
    Publication date: August 24, 2006
    Inventors: Kenichiro Kataoka, Naotaka Suzuki, Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Aiko Fujino, Yasuhiro Oue, Yuko Yamakoshi, Satoshi Sugiura, Robert Mitchell, James Simpson, John Harris, Joelle Le
  • Pyrazolo[1,5-a]pyrimidine derivatives
    Publication number: 20060135514
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Application
    Filed: August 12, 2005
    Publication date: June 22, 2006
    Inventors: Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Kenichiro Kataoka, Dale Mitchell, Donald Simpson, Clifford Harris, Joelle Le, Yuko Yamakoshi