Patents by Inventor Yulong TAN

Yulong TAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphotericin B and ?-1,3-glucanase loaded bi-functional nano-system with both targets, preparation method and application thereof
    Patent number: 11758905
    Abstract: The invention belongs to the technical field of nano-drugs, and in particular, relates to an amphotericin B (AmpB) and ?-1,3-glucanase (Gls) loaded bi-functional nano-system with both targets, a preparation method and an application thereof. The nano-system provided by the invention comprises Gls and AmpB loaded chitosan nanoparticles. The ?-1,3-glucanase modified chitosan nanoparticles are constructed for the first time, which can achieve a bi-functional nano-system both targeting fungal biofilm exopolysaccharide ?-1,3-glucan and internal thalli; meanwhile, the ?-1,3-glucanase and the amphotericin B have a synergistic interaction effect, so that the removal capacity is improved. The double-loaded nano-system is used for fungal biofilm damage removal for the first time.
    Type: Grant
    Filed: February 22, 2022
    Date of Patent: September 19, 2023
    Assignee: QINGDAO AGRICULTURAL UNIVERSITY
    Inventors: Yulong Tan, Su Ma
  • AMPHOTERICIN B AND BETA-1,3-GLUCANASE LOADED BI-FUNCTIONAL NANO-SYSTEM WITH BOTH TARGETS, PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20220346373
    Abstract: The invention belongs to the technical field of nano-drugs, and in particular, relates to an amphotericin B (AmpB) and ?-1,3-glucanase (Gls) loaded bi-functional nano-system with both targets, a preparation method and an application thereof. The nano-system provided by the invention comprises Gls and AmpB loaded chitosan nanoparticles. The ?-1,3-glucanase modified chitosan nanoparticles are constructed for the first time, which can achieve a bi-functional nano-system both targeting fungal biofilm exopolysaccharide ?-1,3-glucan and internal thalli; meanwhile, the ?-1,3-glucanase and the amphotericin B have a synergistic interaction effect, so that the removal capacity is improved. The double-loaded nano-system is used for fungal biofilm damage removal for the first time.
    Type: Application
    Filed: February 22, 2022
    Publication date: November 3, 2022
    Inventors: Yulong TAN, Su MA