Patents by Inventor Yumei RONG

Yumei RONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method and application of novel injection abiraterone derivative
    Patent number: 11944685
    Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.
    Type: Grant
    Filed: March 14, 2022
    Date of Patent: April 2, 2024
    Assignee: TIANJIN HAIRUNJAHE INNOVATIVE PHARMACEUTICAL RESEARCH LIMITED LIABILITY COMPANY
    Inventors: Tianjun Liu, Na Zhu, Yumei Rong, Ge Hong
  • PREPARATION METHOD AND APPLICATION OF NOVEL INJECTION ABIRATERONE DERIVATIVE
    Publication number: 20240042041
    Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.
    Type: Application
    Filed: March 14, 2022
    Publication date: February 8, 2024
    Inventors: Tianjun LIU, Na ZHU, Yumei RONG, Ge HONG