Patents by Inventor Yumiko Nagasaka

Yumiko Nagasaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxylic acid derivatives having fused rings
    Patent number: 6358995
    Abstract: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism. A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: {wherein the symbol represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: —O— or —S—, or a group represented by the formula: [wherein Rk (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R7 and R8 being a group represented by the formula: (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: March 19, 2002
    Assignee: Eisai Co., Ltd.
    Inventors: Katsuya Tagami, Hiroyuki Yoshimura, Mitsuo Nagai, Shigeki Hibi, Kouichi Kikuchi, Takashi Sato, Makoto Okita, Yasushi Okamoto, Yumiko Nagasaka, Naoki Kobayashi, Takayuki Hida, Kenji Tai, Naoki Tokuhara, Seiichi Kobayashi
  • Fused-ring carboxylic acid derivatives
    Patent number: 6121309
    Abstract: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism.A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ----- represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR2## [wherein R.sup.k (k:1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR3## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: September 19, 2000
    Assignee: Eisai Co., Ltd.
    Inventors: Katsuya Tagami, Hiroyuki Yoshimura, Mitsuo Nagai, Shigeki Hibi, Kouichi Kikuchi, Takashi Sato, Makoto Okita, Yasushi Okamoto, Yumiko Nagasaka, Naoki Kobayashi, Takayuki Hida, Kenji Tai, Naoki Tokuhara, Seiichi Kobayashi
  • Carboxylic acid derivatives having fused rings
    Patent number: 6110959
    Abstract: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism.A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ##STR2## represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR3## [wherein R.sup.k (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR4## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: August 29, 2000
    Assignee: Eisai Co., Ltd.
    Inventors: Katsuya Tagami, Hiroyuki Yoshimura, Mitsuo Nagai, Shigeki Hibi, Kouichi Kikuchi, Takashi Sato, Makoto Okita, Yasushi Okamoto, Yumiko Nagasaka, Naoki Kobayashi, Takayuki Hida, Kenji Tai, Naoki Tokuhara, Seiichi Kobayashi