Patents by Inventor Yumiko Ogasawara

Yumiko Ogasawara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Strain belonging to the genus and being capable of producing nemadictin and process for producing nemadictin using the strain
    Patent number: 7670827
    Abstract: In the present invention, a recombination of gene groups of nemadectin aglycon biosynthesis is performed for obtaining C-13 hydroxylnemadectin, to which sugar groups can be attached, and a production strain which produces C-13 hydroxylnemadectin is produced. Further, C-13 glycosylnemadectin producing strain is prepared by introducing aveBI-BVIII genes involving glycosidation of avermectin and biosynthesis of oleandrose. As described, C-13 hydroxylnemadectin and C-13 glycosidated nemadectin can be obtained effectively by using the producing strain prepared by means of the molecular genetic technology, and improvement in the biological activity thereof can be expected.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: March 2, 2010
    Assignee: The Kitasato Institute
    Inventors: Satoshi Omura, Haruo Ikeda, Yumiko Ogasawara
  • Strain belonging to the genus streptomyces and being capable of producing nemadictin and process for producing nemadictin using the strain
    Publication number: 20060234353
    Abstract: In the present invention, a recombination of gene groups of nemadectin aglycon biosynthesis is performed for obtaining C-13 hydroxylnemadectin, to which sugar groups can be attached, and a production strain which produces C-13 hydroxylnemadectin is produced. Further, C-13 glycosylnemadectin producing strain is prepared by introducing aveBI-BVIII genes involving glycosidation of avermectin and biosynthesis of oleandrose. As described, C-13 hydroxylnemadectin and C-13 glycosidated nemadectin can be obtained effectively by using the producing strain prepared by means of the molecular genetic technology, and improvement in the biological activity thereof can be expected.
    Type: Application
    Filed: June 11, 2003
    Publication date: October 19, 2006
    Inventors: Satoshi Omura, Haruo Ikeda, Yumiko Ogasawara