Patents by Inventor Yumin Tao
Yumin Tao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11926833Abstract: The present disclosure relates to a transgenic plant cell comprising polynucleotide sequences encoding glycolate dehydrogenase, malate synthase, and an inhibitory polynucleotide targeting an endogenous glycolate transporter Plgg1, wherein expression of endogenous glycolate transporter Plgg1 in the transgenic plant cell is about 20% to 80% of expression of endogenous glycolate transporter Plgg1 in a plant cell that is not transformed with an inhibitory polynucleotide targeting an endogenous glycolate transporter Plgg1. Also disclosed are transgenic plants, transgenic plant cultures, and methods for increasing photosynthesis efficiency in plants. The disclosed methods enhance biomass productivity and reduce the negative impact of photorespiration and introduction of transgenic constructs on plant growth.Type: GrantFiled: January 12, 2023Date of Patent: March 12, 2024Assignee: LIVING CARBON PBCInventors: Madeline Hall, Li-Wei Chiu, Rebecca Dewhirst, Jacob Hoyle, Patrick Mellor, Karli Rasmussen, Yumin Tao
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Publication number: 20230235336Abstract: The present disclosure relates to a transgenic plant cell comprising polynucleotide sequences encoding glycolate dehydrogenase, malate synthase, and an inhibitory polynucleotide targeting an endogenous glycolate transporter Plgg1, wherein expression of endogenous glycolate transporter Plgg1 in the transgenic plant cell is about 20% to 80% of expression of endogenous glycolate transporter Plgg1 in a plant cell that is not transformed with an inhibitory polynucleotide targeting an endogenous glycolate transporter Plgg1. Also disclosed are transgenic plants, transgenic plant cultures, and methods for increasing photosynthesis efficiency in plants. The disclosed methods enhance biomass productivity and reduce the negative impact of photorespiration and introduction of transgenic constructs on plant growth.Type: ApplicationFiled: January 12, 2023Publication date: July 27, 2023Inventors: MADELINE HALL, Li-Wei CHIU, Rebecca DEWHIRST, Jacob HOYLE, Patrick MELLOR, Karli RASMUSSEN, Yumin TAO
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Patent number: 11225668Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: GrantFiled: January 9, 2019Date of Patent: January 18, 2022Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Yumin Tao, Dennis Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Patent number: 11015206Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: GrantFiled: May 7, 2019Date of Patent: May 25, 2021Inventors: Phillip A Patten, Daniel Siehl, Yumin Tao, Henrik Albert, Ericka Bermudez, Linda A Castle, Yuxia Dong, Andrew Duncan Satterfield
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Publication number: 20200392528Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: ApplicationFiled: March 21, 2018Publication date: December 17, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: YUXIA DONG, JIAN LU, EMILY NG, DANIEL SIEHL, YUMIN TAO
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Publication number: 20190271001Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: ApplicationFiled: May 7, 2019Publication date: September 5, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: PHILLIP A. PATTEN, DANIEL SIEHL, YUMIN TAO, HENRIK ALBERT, ERICKA BERMUDEZ, LINDA A. CASTLE, YUXIA DONG, ANDREW DUNCAN SATTERFIELD
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Publication number: 20190194673Abstract: Methods and compositions using populations of randomized mod fie FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: ApplicationFiled: January 9, 2019Publication date: June 27, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Yumin Tao, Dennis Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Patent number: 10316326Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: GrantFiled: May 2, 2015Date of Patent: June 11, 2019Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Daniel Siehl, Phillip A. Patten, Yumin Tao, Ericka Bermudez, Linda A. Castle, Yuxia Dong, Andrew Duncan Satterfield, Henrik Albert
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Publication number: 20170369893Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: ApplicationFiled: August 30, 2017Publication date: December 28, 2017Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Patent number: 9777284Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: GrantFiled: December 18, 2015Date of Patent: October 3, 2017Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Publication number: 20170058291Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: ApplicationFiled: May 2, 2015Publication date: March 2, 2017Inventors: Daniel Siehl, Phillip A. Patten, Yumin Tao, Ericka Bermudez, Linda A. Castle, Yuxia Dong, Andrew Duncan Satterfield, Henrik Albert
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Publication number: 20160108412Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: ApplicationFiled: December 18, 2015Publication date: April 21, 2016Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Publication number: 20160053277Abstract: Compositions and methods comprising polynucleotides and polypeptides having dicamba decarboxylase activity are provided. Further provided are nucleic acid constructs, host cells, plants, plant cells, explants, seeds and grain having the dicamba decarboxylase sequences. Various methods of employing the dicamba decarboxylase sequences are provided. Such methods include, for example, methods for decarboxylating an auxin-analog, method for producing an auxin-analog tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional dicamba decarboxylase variants.Type: ApplicationFiled: March 14, 2014Publication date: February 25, 2016Inventors: Eric Althoff, Yih-En Andrew Ban, Linda A. Castle, Daniela Grabs, Jian Lu, Phillip A. Patten, Yumin Tao, Alexandre Zanghellini
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Publication number: 20160040149Abstract: Compositions and methods comprising polynucleotides and polypeptides having dicamba decarboxylase activity are provided. Further provided are nucleic acid constructs, host cells, plants, plant cells, explants, seeds and grain having the dicamba decarboxylase sequences. Various methods of employing the dicamba decarboxylase sequences are provided. Such methods include, for example, methods for decarboxylating an auxin-analog, method for producing an auxin-analog tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional dicamba decarboxylase variants.Type: ApplicationFiled: March 14, 2014Publication date: February 11, 2016Inventors: Eric Althoff, Yi-En Andrew Ban, Linda A. Castle, Daniela Grabs, Jian Lu, Phillip A. Patten, Yumin Tao, Alexandre Zanghellini
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Publication number: 20160017351Abstract: Chimeric polynucleotides comprising a nucleotide sequence encoding a chloroplast transit peptide operably linked to a heterologous polynucleotide of interest are provided, wherein the chloroplast transit peptide comprises an amino acid sequence having the chloroplast transit peptide sequence as set forth in SEQ ID NO: 1 or a biologically active variant or fragment thereof or wherein the chloroplast transit peptide comprises the sequence set forth in SEQ ID NO: 58 or an active variant or fragment thereof. Chimeric polypeptides encoding the same, as well as, cells, plant cells, plants and seeds are further provided which comprise the chimeric polynucleotides. Compositions further include HPPD polypeptides and polynucleotides encoding the same as set forth in SEQ ID NOS: 57 and 60 or active variants and fragments thereof. Such sequences comprise the chloroplast transit peptide as set forth in SEQ ID NO: 58 or an active variants or fragments thereof.Type: ApplicationFiled: August 25, 2015Publication date: January 21, 2016Inventors: Henrik Albert, Linda A. Castle, Matthew Heckert, Jian Lu, Daniel L. Siehl, Yumin Tao
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Patent number: 9234194Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.Type: GrantFiled: February 16, 2010Date of Patent: January 12, 2016Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
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Publication number: 20150351390Abstract: Compositions and methods are provided to detoxify an auxin-analog herbicide through the use of at least one GH3 polypeptide having amino acid/auxin analog herbicide conjugation activity. Such GH3 polypeptides in the presence of an auxin-analog herbicide will produce an amino acid/auxin-analog conjugate having reduced herbicidal activity. Various methods of employing the GH3 polypeptides and the polynucleotides encoding the same are provided. Such methods include methods to detoxify an auxin-analog herbicide comprising applying to a plant, a plant cell or a seed an auxin-analog herbicide, wherein the plant, plant cell or seed comprises a heterologous polynucleotide encoding a GH3 polypeptide, and expression of the GH3 polypeptide produces a non-herbicidal aspartate/auxin-analog conjugate or a glutamate/auxin-analog conjugate.Type: ApplicationFiled: December 20, 2013Publication date: December 10, 2015Inventors: Linda A. Castle, Li-Wei Chiu, Yumin Tao
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Patent number: 9187762Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: GrantFiled: August 12, 2011Date of Patent: November 17, 2015Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Henrik Albert, Ericka R. Bermudez, Linda A. Castle, Yuxia Dong, Matthew J. Heckert, Jingtong Hou, Zhenglin Hou, Jian Lu, Daniel L. Siehl, Yumin Tao
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Publication number: 20150275190Abstract: Compositions and methods comprising promoters from the 4-hydroxyphenylpyruvate dioxygenase (HPPD) gene and active variants and fragments thereof, as well as chimeric promoters employing regulatory regions of the HPPD promoters are provided. Further provided are expression cassettes and plants comprising the various promoters disclosed herein operably linked to a polynucleotide of interest. Methods employing the various promoters described herein to modulate the expression of polynucleotides of interest are further provided.Type: ApplicationFiled: February 24, 2015Publication date: October 1, 2015Inventors: Henrik Albert, Linda A. Castle, Jian Lu, Yumin Tao
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Patent number: 9139842Abstract: Chimeric polynucleotides comprising a nucleotide sequence encoding a chloroplast transit peptide operably linked to a heterologous polynucleotide of interest are provided, wherein the chloroplast transit peptide comprises an amino acid sequence having the chloroplast transit peptide sequence as set forth in SEQ ID NO:1 or a biologically active variant or fragment thereof or wherein the chloroplast transit peptide comprises the sequence set forth in SEQ ID NO: 58 or an active variant or fragment thereof. Chimeric polypeptides encoding the same, as well as, cells, plant cells, plants and seeds are further provided which comprise the chimeric polynucleotides. Compositions further include HPPD polypeptides and polynucleotides encoding the same as set forth in SEQ ID NOS: 57 and 60 or active variants and fragments thereof. Such sequences comprise the chloroplast transit peptide as set forth in SEQ ID NO: 58 or an active variants or fragments thereof.Type: GrantFiled: August 12, 2011Date of Patent: September 22, 2015Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Henrik Albert, Linda A. Castle, Matthew Heckert, Jian Lu, Daniel L. Siehl, Yumin Tao