Patents by Inventor Yuming Yu

Yuming Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reduced toxicity molecular conjugates of anti-fungal agents
    Patent number: 10322187
    Abstract: Compositions, compounds and methods are described for addressing both toxicity of membrane disruptive anti-microbial agents as well as poor transport of such agents across the blood-brain-barrier (BBB) via the use of molecular appendages including one or more facial amphiphiles. These molecules have in vitro anti-fungal activity that is very similar to that of the native drug but with hemolytic activity and toxicity towards mammalian cells that is greatly reduced.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: June 18, 2019
    Inventors: Steven L Regen, Vaclav Janout, Yuming Yu
  • REDUCED TOXICITY MOLECULAR CONJUGATES OF ANTI-FUNGAL AGENTS
    Publication number: 20170042923
    Abstract: Compositions, compounds and methods are described for addressing both toxicity of membrane disruptive anti-microbial agents as well as poor transport of such agents across the blood-brain-barrier (BBB) via the use of molecular appendages including one or more facial amphiphiles. These molecules have in vitro anti-fungal activity that is very similar to that of the native drug but with hemolytic activity and toxicity towards mammalian cells that is greatly reduced.
    Type: Application
    Filed: August 10, 2016
    Publication date: February 16, 2017
    Inventors: Steven L. Regen, Vaclav Janout, Yuming Yu