Abstract: The present disclosure relates to a novel citrate synthase variant, a microorganism comprising the variant, and a method for producing O-acetyl-L-homoserine and L-methionine using the microorganism.

Abstract: The present invention relates to an isoindolin-1-on derivative, a method for preparing same, and a pharmaceutical composition comprising same as an effective component for preventing or treating tumors, wherein the isoindolin-1-on derivative exhibits a high inhibitory effect on EGFR mutations, and thus can be beneficially used for the treatment of EGFR-mutated tumors, and the isoindolin-1-on derivative exhibits a significant synergistic effect when co-administered, and thus can be beneficially used in concomitant therapy.

Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: In one example, a semiconductor device can comprise a substrate, a device stack, first and second internal interconnects, and an encapsulant. The substrate can comprise a first and second substrate sides opposite each other, a substrate outer sidewall between the first substrate side and the second substrate side, and a substrate inner sidewall defining a cavity between the first substrate side and the second substrate side. The device stack can be in the cavity and can comprise a first electronic device, and a second electronic device stacked on the first electronic device. The first internal interconnect can be coupled to the substrate and the device stack. The encapsulant can cover the substrate inner sidewall and the device stack and can fill the cavity. Other examples and related methods are disclosed herein.

Abstract: A simulation method and a simulation apparatus of roll press for secondary battery production are provided.

Abstract: A substrate analysis system includes a load-lock module configured to load or unload a substrate on which a pattern layer is formed; a milling module configured to form a milling surface from which at least a portion of the pattern layer is removed; a depth measuring module configured to measure a milling depth of an analysis region formed on the milling surface; an imaging module configured to capture a two-dimensional image of the analysis region; and a control module controlling the substrate to circulate through the milling module, the depth measuring module, and the imaging module, when the milling depth is shallower than a set target depth, wherein the milling module adjusts a path of the ion beam so that the ion beam moves horizontally in the milling region according to a scanning profile received based on an intensity map of the ion beam.

Abstract: A method for manufacturing an electronic device including a semiconductor memory may include forming a first carbon electrode material, surface-treating the first carbon electrode material to decrease a surface roughness of the first carbon electrode material, and forming a second carbon electrode material on the treated surface of the first carbon electrode material. The second carbon electrode material may have a thickness that is greater than a thickness of the first carbon electrode material.

Abstract: The present disclosure relates to a device for providing augmented reality that can accurately recognize a writing tool such as an electronic pen to realize motion information of the writing tool over augmented reality contents, and a method for providing augmented reality using the same. According to some embodiments of the disclosure, an augmented reality device includes at least one transparent lens, a support frame supporting the at least one transparent lens, at least one display module configured to display augmented reality contents through the at least one transparent lens, a sensing module at a front of the support frame, and configured to generate image data, and a control module configured to receive motion-sensing signals of an electronic pen to detect motion information of the electronic pen, and configured to modulate the augmented reality contents so that the motion information of the electronic pen is includes therein.

Abstract: A three-dimensional (3D) semiconductor device includes a stack structure including first and second stacks stacked on a substrate. Each of the first and second stacks includes a first electrode and a second electrode on the first electrode. A sidewall of the second electrode of the first stack is horizontally spaced apart from a sidewall of the second electrode of the second stack by a first distance. A sidewall of the first electrode is horizontally spaced apart from the sidewall of the second electrode by a second distance in each of the first and second stacks. The second distance is smaller than a half of the first distance.

Abstract: An apparatus for estimating a camera pose according to an embodiment of the present disclosure includes a similar image searcher, a clusterer, and an estimator. The similar image searcher searches for a plurality of images similar to an input image, from among a plurality of previously-stored images, based on the input image. The clusterer creates a cluster including at least some similar images meeting predetermined conditions, from among the plurality of similar images, based on viewpoint data tagged to each of the plurality of similar images. The estimator estimates a pose of a camera that has generated the input image, based on the cluster.

Abstract: Provided is an organic compound which contributes to substantial improvements in the luminous efficiency and viewing angle of an organic electroluminescent device. An organic electroluminescent device includes: a first electrode; a second electrode; an organic layer disposed between the first electrode and the second electrode; and a capping layer. The organic layer or the capping layer includes an organic compound represented by chemical formula 1.

Abstract: A display panel includes a base layer including a first area and a second area. At least one inorganic layer disposed on the base layer overlaps the first area and the second area. The at least one inorganic layer comprises a lower opening. A first thin-film transistor is disposed on the at least one inorganic layer. The first thin-film transistor includes a silicon semiconductor pattern. A second thin-film transistor is disposed on the at least one inorganic layer. The second thin-film transistor includes an oxide semiconductor pattern. A plurality of insulation layers overlap the first area and the second area. An upper opening extends from the lower opening. A signal line is electrically connected to the second thin-film transistor. An organic layer is disposed in the lower opening and the upper opening. A light emitting element is disposed on the organic layer.

Abstract: An exemplary semiconductor device can comprise (a) a substrate comprising a substrate dielectric structure between the substrate top side and the substrate bottom side, conductive pads at the substrate bottom side, and a substrate cavity through the substrate dielectric structure, (b) a base electronic component comprising inner short bumps; outer short bumps bounding a perimeter around the inner short bumps, and tall bumps between the outer short bumps and an edge of the base component top side, and (c) a mounted electronic component coupled to the inner short bumps of the base electronic component. The tall bumps of the base component can be coupled to the conductive pads of the substrate. The mounted electronic component can be located in the substrate cavity. The substrate bottom side can cover at least a portion of the outer short bumps of the base electronic component. Other examples and related methods are disclosed herein.

Abstract: Provided are a display device including a resin containing a repeating unit represented by chemical formula (1), a resin composition comprising the resin, and a pixel separation unit formed of the resin composition, in which the display device is a display device including a first electrode formed on a substrate, a pixel separation unit formed on the first electrode to partially expose the first electrode, and a second electrode installed to face the first electrode, and the pixel separation unit has an absorbance of 0.5/?m or more at a wavelength of 550 nm.

Abstract: The present disclosure relates to a simulation apparatus for secondary battery production.

Abstract: The present disclosure provides a compound of a chemical structure having the ability of inhibiting or disintegrating an androgen receptor (AR), or a pharmaceutically acceptable salt of the compound. The present disclosure also provides a composition comprising such a compound or a pharmaceutically acceptable salt thereof. The present disclosure provides a pharmaceutical use of a compound according to the present disclosure, a salt thereof, and a composition comprising same for the treatment or prevention of AR-related diseases. The present disclosure also provides a method for treating or preventing AR-related diseases, comprising administering to a subject in need of treatment an effective amount of a compound according to the present disclosure, a salt thereof, or a composition comprising same.

Abstract: A mounting system for a heating, ventilation, and air conditioning (HVAC) component, including a dash panel configured to divide a front compartment from a passenger compartment, and having an opening, a plurality of mounting portions located around the opening, and configured to mount the HVAC component, and a vertical reinforcing member located adjacent to the opening, and extending along the height of the dash panel. The dash panel includes a first surface facing the front compartment and a second surface facing the passenger compartment, and at least some of the plurality of mounting portions are provided to the vertical reinforcing member.

Abstract: The present disclosure relates to a non-contact type pile cutting apparatus using a waterjet, particularly to a pile cutting apparatus entering the inside for cutting a pile including: a body that has a pipe form and is put into an inside of the pile; a gripper unit that is provided at an outer side of the body and fixes the body to the pile when the pile cutting apparatus has reached a cutting position of the pile; a waterjet unit that is provided at one side of the body and fixed by the gripper unit, and then sprays an abrasive mixture in which an abrasive and a fluid are mixed, toward the pile in a high pressure; a rotation unit that rotates the waterjet unit around a central axis of the body; a feed line that feeds the abrasive mixture in which the fluid and the abrasive of a set ratio are mixed, to the waterjet unit from the outside; a feed unit that controls a feed pressure of the abrasive mixture fed through the feed line; and a nozzle driving unit that controls a position of the waterjet unit.

Abstract: An adhesive film for polarizing plates, a polarizing plate including the same, and an optical display including the same are provided. The adhesive film for polarizing plates is formed of an adhesive composition comprising: a (meth)acrylic copolymer; an adhesion promoter; a mixture of an isocyanate curing agent and a carbodiimide curing agent; and a UV absorbent, and the adhesive film has a glass transition temperature of about ?47° C. to ?40° C., and the adhesive film has a light transmittance of about 3% or less at a wavelength of about 380 nm.

Abstract: The present disclosure relates to an offshore substructure supported by a template-integrated suction foundation and an installation method thereof, more particularly to an offshore substructure installed by pre-piling construction including: a suction foundation having a plurality of suction piles pre-inserted into the seabed by suction, joint sockets connected to each head part of the suction piles, and connecting members connecting spaces between the joint sockets; and a substructure connected onto an upper part of a suction foundation pre-piled, wherein an insertion socket connected to a lower part of the substructure is inserted into the joint socket, and the suction foundation and the substructure are connected by grouting a space between the insertion socket and the joint socket.