Abstract: A data collecting system including a component assembled in an electric vehicle, a data collector connected to the component through a bus of the electric vehicle, and a debug server connected to the data collector is disclosed. The component collects different data from the electric vehicle and performs different sending procedures respectively under different situations including: a regular sending-procedure sends regular data to the bus based on a regular frequency; a high-speed sending-procedure starts collecting high-speed data and sending the same to the bus based on a high-speed frequency after a condition is satisfied; and a high-resolution sending-procedure sends high-resolution data to the bus after an error occurs, wherein the high-resolution data is collected within a period of time before and after the error occurs. The data collector collects these data from the bus. The debug server analyzes the data collected by the data collector.

Abstract: Disclosed herein is a hinge antibody capable of being selectively activated in a target cell or tissue to treat a condition therein. The hinge antibody includes a functional antibody, two inhibitory domains and four cleavable linkers. The functional antibody is capable of treating the condition in an activated state, and has two light chains and two heavy chains. Each inhibitory domain includes a hinge domain of an immunoglobulin and consists of two peptide arms. Each cleavable linker includes a peptide substrate cleavable by an enzyme specifically or highly expressed in the target cell or tissue, and connects one of the peptide arms of the inhibitory domains to the N-terminal of one of the light chains and heavy chains of the functional antibody. Also disclosed herein are methods for preparing and using this hinge antibody.

Abstract: Disclosed herein is a hinge antibody capable of being selectively activated in a target cell or tissue to treat a condition therein. The hinge antibody includes a functional antibody, two inhibitory domains and four cleavable linkers. The functional antibody is capable of treating the condition in an activated state, and has two light chains and two heavy chains. Each inhibitory domain includes a hinge domain of an immunoglobulin and consists of two peptide arms. Each cleavable linker includes a peptide substrate cleavable by an enzyme specifically or highly expressed in the target cell or tissue, and connects one of the peptide arms of the inhibitory domains to the N-terminal of one of the light chains and heavy chains of the functional antibody. Also disclosed herein are methods for preparing and using this hinge antibody.