Patents by Inventor Yun DONG

Yun DONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040106136
    Abstract: Methods, compositions and kits are provided for testing susceptibility of HIV to drug treatment, such as drug resistance of HIV and inhibition of HIV replication by a drug candidate. In one aspect of the invention, a method is provided for detecting drug resistance of HIV contained in a sample from an individual infected with HIV. In one embodiment, the method employs an indicator cell line which over-expresses CD4 and one or more co-receptors for HIV such as CXCR4 and CCR5 at high levels to render the cells susceptible to productive infection of various strains, subtypes or clades of HIV from both laboratory and clinical isolates. The methods, compositions and kits can be used for high throughput screening of HIV patient samples, anti-HIV agents, and for designing customized HIV therapy.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 3, 2004
    Applicant: MUSC Foundation for Research Development
    Inventor: Jian-yun Dong
  • Publication number: 20030064054
    Abstract: Methods are provided for screening natural and synthetic anti-HIV agents using recombinant cells that are rendered susceptible to productive infection of various strains, subtypes or clades of HIV from both laboratory and clinical isolates.
    Type: Application
    Filed: September 13, 2002
    Publication date: April 3, 2003
    Inventor: Jian-Yun Dong
  • Publication number: 20020168345
    Abstract: Recombinant expression vectors and methods are provided for detecting HIV and monitoring HIV drug resistance.
    Type: Application
    Filed: March 29, 2002
    Publication date: November 14, 2002
    Inventor: Jian-Yun Dong
  • Publication number: 20020132347
    Abstract: a method is provided for detecting a presence of HIV virus in a sample comprising: taking a culture of recombinant cells which (a) are capable of cell division, (b) express CD4 receptor and one or more additional cell surface receptors necessary to allow the HIV virus to infect, (c) enable the HIV virus to replicate and infect the noninfected cells in the cell culture, and (d) comprise a reporter sequence introduced into the recombinant cells comprising a reporter gene whose expression is regulated by a protein specific to HIV viruses which is expressed from a genome of an HIV virus upon infection of the recombinant cell by the HIV virus; contacting the cell culture with a sample to be analyzed for the presence of HIV virus in the sample; and detecting a change in a level of expression of the reporter gene in cells in the recombinant cell culture.
    Type: Application
    Filed: March 29, 2002
    Publication date: September 19, 2002
    Inventor: Jian-yun Dong
  • Patent number: 6410013
    Abstract: Recombinant expression vectors and methods are provided for detecting HIV and monitoring HIV drug resistance.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: June 25, 2002
    Assignee: Musc Foundation for Research Development
    Inventor: Jian-yun Dong
  • Patent number: 6294379
    Abstract: The present invention provides improved AAV vectors for delivery of therapeutic nucleic acids. In particular, it provides vectors for delivery of CFTR polynucleotides.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: September 25, 2001
    Assignee: The Regents of the University of California
    Inventors: Jian-Yun Dong, Yuet Wai Kan
  • Patent number: 5611368
    Abstract: A valve having a magnetic force transmission apparatus is disclosed including: a closed body for tightly closing internal components and rotation shaft of the body of the valve, so as to interrupt the leakage of fluid from the valve and maintain perfect airtightness; and a pair of permanent magnet plates opposingly placed in the closed body and for allowing the valve open/close by transmitting power using the magnetic force of magnet pieces attached on yokes in non-contact.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: March 18, 1997
    Assignee: Korea Atomic Energy Research Institute
    Inventors: Sung-Tai Hwang, Jong-Hyeun Choi, Tae-Joon Kim, Yun-Dong Choi, Byung-Real Jo
  • Patent number: D488479
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: April 13, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Yun-Dong Xu, Perry Chih Wei Hsu, Ding-Ding Zhang, Tao Su, Xin-Jian Xiao
  • Patent number: D495697
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: September 7, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Xin-Jian Xiao, Chun-Chi Liang, Yun-Dong Xu, Tao Su
  • Patent number: D498238
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: November 9, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Xin-Jian Xiao, Chun Chi Liang, Yun-Dong Xu, Tao Su
  • Patent number: D499099
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Tao Su, Chun Chi Liang, Yun-Dong Xu, Xin-Jian Xiao
  • Patent number: D499102
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., LTD
    Inventors: Xin-Jian Xiao, Chun Chi Liang, Yun-Dong Xu, Ding-Ding Zhang
  • Patent number: D499103
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Tao Su, Chun Chi Liang, Yun-Dong Xu, Ding-Ding Zhang
  • Patent number: D499104
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Xin-Jian Xiao, Chun Chi Liang, Yun-Dong Xu, Ding-Ding Zhang
  • Patent number: D499105
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Xin-Jian Xiao, Chun Chi Liang, Yun-Dong Xu, Tao Su
  • Patent number: D499106
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Tao Su, Chun Chi Liang, Yun-Dong Xu, Xin-Jian Xiao
  • Patent number: D499107
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: November 30, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Tao Su, Chun Chi Liang, Yun-Dong Xu, Xin-Jian Xiao
  • Patent number: D499405
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: December 7, 2004
    Assignee: Hon Hai Precision Ind. Co., LTD
    Inventors: Ding-Ding Zhang, Chun Chi Liang, Yun-Dong Xu, Xin-Jian Xiao
  • Patent number: D499411
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: December 7, 2004
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Tao Su, Chun Chi Liang, Yun-Dong Xu, Ding-Ding Zhang