Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: One embodiment of the present invention provides a method of manufacturing an electronic device using a cyclic doping process including i) an operation of forming a unit transfer thin film including a two-dimensional material on a transfer substrate, ii) an operation of doping the unit transfer thin film in a low-damage doping process, iii) an operation of transferring the unit transfer thin film doped according to the operation ii) on a transfer target substrate, and iv) an operation of repeatedly performing the operations i) to iii) several times to reach a target thickness.

Abstract: The present invention relates to an observation apparatus which changes and moves planar position coordinates of a moving object connected to an observation unit, so as to adjust an observation direction of the observation unit and a change speed of the observation direction, such that objects moving at low to high speeds can be tracked and observed, and objects in the celestial direction can be observed.

Abstract: A color conversion panel includes a first color filter and a second color filter that are disposed on a substrate, a low refractive index layer disposed on the substrate, the first color filter, and the second color filter, the low refractive index layer including at least one of a first blue pigment and a first blue dye, a first color conversion layer overlapping the first color filter and including a semiconductor nanocrystal, a second color conversion layer overlapping the second color filter and including a semiconductor nanocrystal, and a transmissive layer that overlaps the low refractive index layer.

Abstract: The present invention relates to a device and method for implementing dynamic-service-oriented communication between vehicle applications on an AUTomotive Open System ARchitecture (AUTOSAR) adaptive platform (AP). A machine including an electronic control unit (ECU) to which the portable operating system interface (POSIX) operating system (OS) is ported and implementing dynamic-service-oriented communication between vehicle applications on an AUTOSAR AP includes a skeleton which is an application for providing a service on the platform, a proxy which is an application using the service on the platform, and a service communication management (CM) which is an application for brokering service-oriented communication between vehicle applications on the platform.

Abstract: Various embodiments generally relate to a power distribution network and a semiconductor device, which may include: a plurality of chip pads; a first distribution layer in which a plurality of first conductive lines having rectangular shapes of different sizes, respectively, are disposed; a second distribution layer in which a plurality of second conductive lines including a central cross-shaped conductive line and L-shaped conductive lines open toward respective corners of the second distribution layer are disposed; and a redistribution layer electrically coupling chip pads to which power is applied among the plurality of chip pads and the first conductive lines of the first distribution layer.

Abstract: A cleaning apparatus including a vacuum cleaner and a docking station is provided. The cleaning apparatus includes a vacuum cleaner including a dust collecting chamber in which foreign substances are collected, and a docking station configured to be connected to the dust collecting chamber to remove the foreign substances collected in the dust collecting chamber. The dust collecting chamber is configured to collect foreign substances through centrifugation, and configured to be docked to the docking station, and the docking station includes a suction device configured to suction the foreign substances and air in the dust collecting chamber docked to the docking station.

Abstract: Provided is a method for purifying an anti-4-1BB/anti-HER2 bispecific antibody, the method of which includes carrying out affinity chromatography with a sodium acetate buffer containing a certain inorganic salt as an elution buffer. The purification method of the presently claimed subject matter increases the elution of an antibody in the intact form, thereby being able to provide an anti-4-1BB/anti-HER2 bispecific antibody in the intact form in high purity and high yield.

Abstract: A negative electrode for a lithium secondary battery contains a lithium-magnesium-aluminum alloy. A method for preparing the same and a lithium secondary battery, such as a lithium sulfur battery, containing the same are also provided.

Abstract: Provided are a curcumin nanoparticle complex having a modified particle surface and a method for preparing same. A curcumin nanoparticle complex includes curcumin and phospholipids and has a particle size of less than 1000 nm. A first coating layer containing a cationic material and/or a second coating layer containing an anionic material can be further added.

Abstract: A negative electrode includes a lithium-lanthanum alloy. The negative electrode can be applied to a negative electrode for a lithium-sulfur battery. The lithium-sulfur battery including the alloy negative electrode has improved life characteristics and improved electrochemical efficiency.

Abstract: A negative electrode includes a lithium-alkaline earth metal alloy, and can be used in a lithium-sulfur battery. Furthermore, a method to obtain said negative electrode, and a lithium-sulfur battery containing the negative electrode.

Abstract: An electronic device and an application sharing method thereof are provided. The electronic device includes a display; and a controller electrically connected to the display, wherein the controller is configured to receive first data which is partial data of entire data of an application from a first electronic device; and when a user agrees to use condition information of an application received from a second electronic device, receive second data which is remaining data of the entire data of the application from the second electronic device, and generate the entire data of the application.

Abstract: An electronic device and an application sharing method thereof are provided. The electronic device includes a display; and a controller electrically connected to the display, wherein the controller is configured to receive first data which is partial data of entire data of an application from a first electronic device; and when a user agrees to use condition information of an application received from a second electronic device, receive second data which is remaining data of the entire data of the application from the second electronic device, and generate the entire data of the application.