Abstract: Provided are methods and compositions for the prevention and treatment of diabetes complications. The methods include administration of pharmaceutical compounds containing a novel chrysin derivative compound as an active ingredient. More specifically, the pharmaceutical compositions inhibit the formation of an advanced glycation end product (AGE) thereby preventing or treating diabetes complications.

Abstract: Disclosed is a pharmaceutical composition for preventing or treating diabetes complications comprising a novel chrysin derivative compound as an active ingredient and, more specifically, a pharmaceutical composition for preventing or treating diabetes complications containing, as an active ingredient, a novel chrysin derivative compound that is capable of preventing or treating diabetes complications due to the ability thereof to inhibit the formation of an advanced glycation end product (AGE).