Patents by Inventor Yun Joon Jung

Yun Joon Jung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS
    Publication number: 20240360451
    Abstract: Described herein are methods of modulating OTC gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for increasing expression of Ornithine transcarbamylase (OTC), thereby treating diseases associated with aberrant gene expression.
    Type: Application
    Filed: September 2, 2022
    Publication date: October 31, 2024
    Inventors: Alfica Sehgal, Bryan J. Matthews, Cynthia M. Smith, David A. Bumcrot, Justin A. Caravella, Mario Esteban Contreras Gamboa, Rachana S. Kelkar, Yun Joon Jung, Yuting Liu, Subhadeep Roy, Brynn Nicole-Yoshiko Akerberg, Rutuja Sudhakar Pai
  • MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS
    Publication number: 20240336924
    Abstract: Described herein are methods of modulating gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for modulating the levels of gene products, for example, increasing expression of Carbamoyl-Phosphatase Synthetase 1 (CPS1), thereby treating diseases associated with aberrant gene expression.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 10, 2024
    Inventors: Alfica Sehgal, Bryan J. Matthews, David A. Bumcrot, Justin A. Caravella, Mario Esteban Contreras Gamboa, Rachana S. Kelkar, Yun Joon Jung, Yuting Liu, Rutuja Sudhakar Pai, Henry Munir Moukheiber, Subhadeep Roy, Yuchun Guo
  • METHODS AND COMPOSITIONS FOR TREATING UREA CYCLE DISORDERS
    Publication number: 20220168316
    Abstract: Provided are methods and compositions for the treating a patient with a urea cycle disorder. Methods and compositions are also provided for modulating genes encoding enzymes that participate in the urea cycle by altering gene signaling networks.
    Type: Application
    Filed: January 27, 2022
    Publication date: June 2, 2022
    Inventors: Alfica Sehgal, Alla A. Sigova, Igor Zlobine, Brian E. Schwartz, David A. Bumcrot, Vaishnavi Rajagopal, Yun Joon Jung, Yuichi Nishi
  • Methods and compositions for treating urea cycle disorders
    Patent number: 11266655
    Abstract: Provided are methods and compositions for the treating a patient with a urea cycle disorder. Methods and compositions are also provided for modulating genes encoding enzymes that participate in the urea cycle by altering gene signaling networks.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: March 8, 2022
    Assignee: CAMP4 THERAPEUTICS CORPORATION
    Inventors: Alfica Sehgal, Alla A. Sigova, Igor Zlobine, Brian E. Schwartz, David A. Bumcrot, Vaishnavi Rajagopal, Yun Joon Jung, Yuichi Nishi
  • METHODS AND COMPOSITIONS FOR TREATING UREA CYCLE DISORDERS
    Publication number: 20210114996
    Abstract: Provided are methods and compositions for the treating a patient with a urea cycle disorder. Methods and compositions are also provided for modulating genes encoding enzymes that participate in the urea cycle by altering gene signaling networks.
    Type: Application
    Filed: December 14, 2020
    Publication date: April 22, 2021
    Inventors: Alfica Sehgal, Alla A. Sigova, Igor Zlobine, Brian E. Schwartz, David A. Bumcrot, Vaishnavi Rajagopal, Yun Joon Jung, Yuichi Nishi