Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: A transparent conductor according to an exemplary embodiment of the present invention includes a transparent substrate, and a transparent conductive pattern formed on the transparent substrate, and the transparent conductor includes a nanostructure on an upper surface of at least one of the transparent substrate and the transparent conductive pattern.

Abstract: The present invention relates to a method and apparatus for encoding a displacement video using image tiling. A method for encoding multi-dimensional data according to an embodiment of the present disclosure may comprise: converting the multi-dimensional data into one or more frames with two-dimensional characteristics; generating one or more frame groups by grouping the one or more frames with pre-configured number units; reconstructing frames belonging to each frame group into a tiled frame; and generating a bitstream by encoding the tiled frame. Here, the tiled frame may be constructed with one or more blocks, and each block may be constructed by rearranging pixels existing at the same location in the frames.

Abstract: A method and system for maintaining command queue order are disclosed. According to certain embodiments, commands are read from a host, storing command queue IDs in an array that will keep the queue IDs in order. After having the queue IDs stored in the array, the commands are processed in the data storage device (DSD). After processing, the commands are provided to a completion order adjustment module that will order the commands in queue ID order for sequential commands to be returned to the host. In certain embodiments, for a sequential command, other commands of the same sequence are searched for the array and ordered with the sequential command. If a particular command of the sequence is not found, the completion order adjustment module will wait to transfer the sequence until each command of the sequence is found. For commands not part of a sequence, these commands are transferred to the host.

Abstract: A composition for strengthening, developing, differentiating, or regenerating muscle, or preventing, ameliorating, or treating muscle loss or muscle fatigue includes a Schizonepeta tenuifolia extract as an effective component. The Schizonepeta tenuifolia extract as an effective component has the effects of restoring the viability of muscle cells, increasing the endurance time on the rotarod performance test, i.e., the holding time without falling off from the rod, compared to the control group, reducing the content of LDH, AST, and ALT in blood, increasing the grip strength, enhancing the expression amount of energy metabolism-related genes in muscle tissues, increasing the density of muscle fibers in muscle tissues, inducing a change in the fibroblast arrangement to have a well-organized structure, and reducing the expression of MuRF1 in muscle tissues, as compared to the control group.

Abstract: A circuit check method and an electronic apparatus applicable to a to-be-tested circuit are provided. The to-be-tested circuit has one or more first nodes related to a gate voltage of one or more transistor devices and a plurality of second nodes. The circuit check method includes: setting endpoint voltages of a plurality of input interface ports of the to-be-tested circuit; obtaining a first node voltage of the first node according to a conduction path of the to-be-tested circuit and the gate voltage of the transistor device; obtaining a second node voltage of each second node according to the conduction path, the endpoint voltages, and the first node voltage; and performing circuit static check on the to-be-tested circuit by applying the first node voltage and the second node voltage.

Abstract: An object detection method is suitable for a virtual reality system. The object detection method includes a plurality of first cameras of a head-mounted display (HMD) to capture a plurality of first frames. A plurality of second frames are captured through a plurality of second cameras in a tracker, wherein, the object detector searches for the object position in the first frames and the second frames.

Abstract: The present invention is a pharmaceutical or food composition comprising a pretreated extract and an isolate and an isolated and purified product of Cinnamomum cassia showing a pharmacological effect. It relates to an active ingredient showing physiological activity in the Cinnamomum cassia extract.

Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.

Abstract: A semiconductor device and a method of manufacturing the same are provided. The semiconductor device includes a first transistor, a first resistive random access memory (RRAM) resistor, and a second RRAM resistor. The first resistor includes a first resistive material layer, a first electrode shared by the second resistor, and a second electrode. The second resistor includes the first electrode, a second resistive material layer, and a third electrode. The first electrode is electrically coupled to the first transistor.

Abstract: A semiconductor structure includes a substrate with a first surface and a second surface opposite to the first surface, a first and a second shallow trench isolations disposed in the substrate and on the second surface, a deep trench isolation structure in the substrate and coupled to the first shallow trench isolation, a first dielectric layer disposed on the first surface and coupled to the deep trench isolation structure, a second dielectric layer disposed over the first dielectric layer and coupled to the deep trench isolation structure, a third dielectric layer comprising a horizontal portion disposed over the second dielectric layer and a vertical portion coupled to the horizontal portion, and a through substrate via structure penetrating the substrate from the first surface to the second surface and penetrating the second shallow trench isolation.

Abstract: A computing method for privacy-preserving data analysis is provided, in which the computing method is performed by at least one processor and includes receiving a data analysis request including data-to-be-analyzed from a client, homomorphically encrypting the data-to-be-analyzed using an encryption engine, and uploading the homomorphically encrypted data-to-be-analyzed to a target path of a blockchain, and then, the method includes, based on the request to check analysis result, decrypting an analysis result of the homomorphically encrypted data stored in a designated path of the blockchain by using the encryption engine, and providing the decrypted analysis result to the client, in which the analysis result of the homomorphically encrypted data is data analyzed by a worker linked to the blockchain, and stored in a designated path in association with the target path of the blockchain.

Abstract: A negative electrode for a lithium secondary battery contains a lithium-magnesium-aluminum alloy. A method for preparing the same and a lithium secondary battery, such as a lithium sulfur battery, containing the same are also provided.

Abstract: A negative electrode includes a lithium-alkaline earth metal alloy, and can be used in a lithium-sulfur battery. Furthermore, a method to obtain said negative electrode, and a lithium-sulfur battery containing the negative electrode.

Abstract: A negative electrode includes a lithium-lanthanum alloy. The negative electrode can be applied to a negative electrode for a lithium-sulfur battery. The lithium-sulfur battery including the alloy negative electrode has improved life characteristics and improved electrochemical efficiency.

Abstract: A method for fabricating a high electron mobility transistor (HEMT) includes the steps of forming a buffer layer on a substrate, forming a barrier layer on the buffer layer, forming a p-type semiconductor layer on the barrier layer, forming a gate electrode layer on the p-type semiconductor layer, and patterning the gate electrode layer to form a gate electrode. Preferably, the gate electrode includes an inclined sidewall.

Abstract: A photoresist film and application thereof are provided. The photoresist film has a thickness T with a unit of ?m, and when the photoresist film is characterized by ultraviolet-visible spectroscopy, the photoresist film has an absorbance A405nm at 405 nm and an absorbance A436nm at 436 nm, wherein 0<A405nm/T?0.006 and 0<A436nm/T?0.005, and the thickness T is 60 ?m to 600 ?m.

Abstract: A water shortage detection system comprises: a body; a drive unit which is provided in the body to supply power for traveling of a robot cleaner; a plurality of rotary members which rotate about a plurality of respective rotation axes by the power from the drive unit and to which cleaners for wet cleaning of a surface to be cleaned can be fixed respectively; a water tank which is provided in the body to store water; a pump motor which supplies water stored in the water tank to the rotary members; and a control unit which measures the load current of the pump motor, wherein a water shortage state in the water tank is detected on the basis of the measured value of the load current of the pump motor.

Abstract: A method, an electronic device, and a non-transitory computer readable storage medium for interacting with a virtual reality (VR) environment are provided. The method includes: displaying a first portal in a first virtual scene of the virtual reality environment, wherein the first portal is for a virtual scene switching, and the first portal comprises a frame; determining whether the frame is dragged toward a center of the first portal; and in response to determining the frame is dragged toward the center of the first portal, removing the first portal from the virtual reality environment.

Abstract: A head-mounted display, content loading method, and non-transitory computer readable storage medium thereof are provided. The head-mounted display selects a first multimedia content from a plurality of multimedia contents in response to receiving a switching signal, and the switching signal is generated based on determining that a user chooses to execute a new application program, and a playing content of the first multimedia content corresponds to the new application program. The head-mounted display transmits the first multimedia content to a display to play the first multimedia content on a plurality of pixels of a display screen.