Patents by Inventor Yun Kyung BAE

Yun Kyung BAE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250073273
    Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of inflammatory disease, comprising mesenchymal stem cells expressing PTX-3, TIMP1, and BDNF as an active ingredient. The mesenchymal stem cells expressing PTX-3, TIMP1, BDNF, and/or HLA-A2, according to the present invention, may inhibit an inflammatory response by reducing the expressions of the inflammatory cytokines IL-1b, IL-6, IL-8, and TNF-a, and increasing the expressions of the anti-inflammatory cytokines IL-10 and arginase-1 (ARG-1), and may relieve pain caused by osteoarthritis when administered in an osteoarthritis-induced rat. Thus, the mesenchymal stem cells expressing PTX-3, TIMP1, and BDNF of the present invention may be usefully employed in the prevention, alleviation, or treatment of inflammatory disease, pain, and pain cuased by inflammation.
    Type: Application
    Filed: November 29, 2021
    Publication date: March 6, 2025
    Applicant: MEDIPOST CO., LTD.
    Inventors: Yoon Sun YANG, Wonil OH, Soo Jin CHOI, Hye Jin JIN, Yun Kyung BAE, Minju LEE
  • Publication number: 20250017975
    Abstract: Proposed is a composition for preventing or treating lung diseases. The composition may contain CD47-overexpressing mesenchymal stem cells as an active ingredient. CD47-overexpressing mesenchymal stem cells, even when not autologous, show a high survival rate in vivo and the ability to migrate to lung tissue, reduce the inflammatory response in lung tissue, and exhibit a fibrosis-inhibiting effect. CD47-overexpressing mesenchymal stem cells can be widely used for the prevention or treatment of various lung diseases related to inflammation or fibrosis of the lungs.
    Type: Application
    Filed: September 21, 2022
    Publication date: January 16, 2025
    Inventors: Yun Sun YANG, Won Il OH, Soo Jin CHOI, Hye Jin JIN, Yun Kyung BAE, Hyang Ju LEE