Patents by Inventor Yun-Long Lin

Yun-Long Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained-release anesthetic compositions and methods of preparation thereof
    Patent number: 11938220
    Abstract: Provided is an anesthetic composition for locally administering a local anesthetic agent to a subject in need thereof. The anesthetic composition has a lipid based complex prepared by hydrating a lipid cake containing a local anesthetic agent and a lipid mixture with an aqueous buffer solution at a pH higher than 5.5. Also provided is a method to prepare an anesthetic composition using a simpler and more robust for large-scale manufacture and for providing a high molar ratio of local anesthetic agent to phospholipid content as compared to the prior art. This anesthetic composition has a prolonged duration of efficacy adapted to drug delivery.
    Type: Grant
    Filed: March 30, 2019
    Date of Patent: March 26, 2024
    Assignees: Taiwan Liposome Co., Ltd, TLC Biopharmaceuticals, Inc.
    Inventors: Keelung Hong, Yun-Long Tseng, Chun-Yen Lai, Wan-Ni Yu, Hao-Wen Kao, Yi-Yu Lin
  • Cecropins fusion proteins
    Patent number: 5357044
    Abstract: Cecropin fusion proteins with suppressed bactericidal activity are provided. The fusion proteins of the invention provide the sequence of a cecropin and can be expressed in a cecropin-sensitive bacterium.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: October 18, 1994
    Assignee: Xoma Corporation
    Inventors: Jiunu Lai, Jar-How Lee, Yun-Long Lin, Dan S. Ray, Gary Wilcox
  • Method of producing cecropins by microbiological techniques
    Patent number: 5206154
    Abstract: A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.
    Type: Grant
    Filed: January 3, 1991
    Date of Patent: April 27, 1993
    Assignee: Xoma Corporation
    Inventors: Jiunu Lai, Jar-How Lee, Yun-Long Lin, Dan Ray, Gary Wilcox
  • AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques
    Patent number: 5028530
    Abstract: A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.
    Type: Grant
    Filed: February 5, 1990
    Date of Patent: July 2, 1991
    Assignee: Xoma Corporation
    Inventors: Jiunu Lai, Jar-How Lee, Yun-Long Lin, Dan Ray, Gary Wilcox