Abstract: A TRS workflow is registered in a cloud-native biomedical informatics platform, and the TRS workflow includes at least one TRS_FQN. A workflow automation execution method applied in the cloud-native biomedical informatics platform includes providing a run sheet used to configure a sequencer to generate a first sequencing data. The run sheet includes a sample-specific metadata associating the first sequencing data, at least one TRS_FQN and a run identifier. The method further includes importing a first DRS object indicating the first sequencing data in response to the run sheet. A first WES_FQN is generated based on the run identifier and the at least one TRS_FQN and attached to the first DRS object. The method further includes performing a WES run running the TRS workflow on the first DRS object in response to the run sheet. The first DRS object is resolved based on the first WES_FQN.

Abstract: The invention provides a smart pad for detecting a physiological state and movement, together or individually, of a user. The smart pad comprises: a sensing portion, having a plurality of sub-sensing portions, wherein the plurality of sub-sensing portions are respectively separated from each other by a plurality of partitions; a channel portion, communicating with one opening of each of the plurality of sub-sensing portions; and a collection portion, communicating with the plurality of sub-sensing portions through the channel region. The physiological state and movement, together or individually, is determined according to a fluid status change in the plurality of sub-sensing portions delivered to the collection portion through the channel portion. The interior of the plurality of partitions is separated from the interiors of the sensing portion, channel region, and collection portion.

Abstract: A portable bioreactor is provided for driving displacement of at least one stirring sleeve relative to at least one tube cassette in a first direction and includes a machine frame unit and a first elevator. The first elevator includes a first linear movement module, a first transmission module, and a first turning module. The first linear movement module includes a first slider which is slidable on the first guide rail in the first direction between a first top position and a first bottom position. The first turning module is coupled to the first slider through the first transmission module so as to permit turning of the first turning module to be translated by the first transmission module into linear sliding movement of the first slider at a varying speed.

Abstract: A cartridge for a bioreactor adapted for accommodating a plurality of objects includes a cartridge main body defining a plurality of spaced-apart accommodating slots for respectively accommodating the objects therein. The cartridge main body includes a retaining portion extending into at least one of the accommodating slots, and adapted to retain a corresponding one of the objects in a corresponding one of the accommodating slots. The retaining portion is pushable to move resiliently in the corresponding one of the accommodating slots.

Abstract: Provided is a heating mechanism for a biochemical reaction device, including: a heat-conducting body including: at least one accommodating groove each including a chamber and an opening communicating with the chamber; a clamping hole, in communication with the opening and for inserting a reaction tube; and at least one heat-conducting block, movably disposed in the chamber and having one end connected with an elastic element and another opposite end provided with an abutting portion, the elastic element enabling the abutting portion of the heat-conducting block to protrude from the opening and locate in the clamping hole; and a temperature control element connected to the heat-conducting body for heating and regulating a temperature of the heat-conducting block.

Abstract: A method for facilitating optimization of a cluster computing network for sequencing data analysis using adaptive data parallelization is provided. The method comprises the following steps. (a) A data parallelization configuration is determined, based on sequencing data and a pipeline selection, wherein the data parallelization configuration includes partition indication data indicating at least one biological information unit based on which of the sequencing data is to be partitioned.

Abstract: A CMP slurry composition which provides for a high Ge- or SiGe-to-dielectric material selectivity a low rate of Ge or SiGe recess formation includes an oxidant and a germanium removal rate enhancer including at least one of a methylpyridine compound and a methylpyridine derivative compound. In some examples, the slurry composition also includes an etching inhibitor. In some cases, the slurry composition may include an abrasive, a surfactant, an organic complexant, a chelating agent, an organic or inorganic acid, an organic or inorganic base, a corrosion inhibitor, or a buffer. The slurry composition may be distributed onto a surface of a polishing pad disposed on a platen that is configured to rotate. Additionally, a workpiece carrier configured to house a substrate may bring the substrate into contact with the rotating polishing pad and thereby polish the substrate utilizing the slurry composition.

Abstract: A portable bioreactor is provided for driving displacement of at least one stirring sleeve relative to at least one tube cassette in a first direction and includes a machine frame unit and a first elevator. The first elevator includes a first linear movement module, a first transmission module, and a first turning module. The first linear movement module includes a first slider which is slidable on the first guide rail in the first direction between a first top position and a first bottom position. The first turning module is coupled to the first slider through the first transmission module so as to permit turning of the first turning module to be translated by the first transmission module into linear sliding movement of the first slider at a varying speed.

Abstract: Provided is a heating mechanism for a biochemical reaction device, including: a heat-conducting body including: at least one accommodating groove each including a chamber and an opening communicating with the chamber; a clamping hole, in communication with the opening and for inserting a reaction tube; and at least one heat-conducting block, movably disposed in the chamber and having one end connected with an elastic element and another opposite end provided with an abutting portion, the elastic element enabling the abutting portion of the heat-conducting block to protrude from the opening and locate in the clamping hole; and a temperature control element connected to the heat-conducting body for heating and regulating a temperature of the heat-conducting block.

Abstract: Provided is a slurry composition including abrasive particles, halogen oxide, and nitroxide compound. The combination of halogen oxide and nitroxide compound has a synergistic effect to remove a substrate containing tungsten and silicon oxide. Moreover, a use of the slurry composition and a polishing method using the slurry composition are provided.

Abstract: Provided is a slurry composition including abrasive particles, halogen oxide, and nitroxide compound. The combination of halogen oxide and nitroxide compound has a synergistic effect to remove a substrate containing tungsten and silicon oxide. Moreover, a use of the slurry composition and a polishing method using the slurry composition are provided.

Abstract: The invention provides a smart pad for detecting a physiological state and movement, together or individually, of a user. The smart pad comprises: a sensing portion, having a plurality of sub-sensing portions, wherein the sub-sensing portions are respectively separated from each other by a plurality of partitions; a channel portion, communicating one opening of each of the sub-sensing portions; and a collection portion, communicating the sub-sensing portions through the channel region. The physiological state and movement, together or individually, is determined according to a fluid status change in the sub-sensing portions delivered to the collection portion through the channel portion. None of state change generated in the partitions corresponds to the physiological state and movement, together or individually.

Abstract: A CMP slurry composition which provides for a high Ge- or SiGe-to-dielectric material selectivity a low rate of Ge or SiGe recess formation includes an oxidant and a germanium removal rate enhancer including at least one of a methylpyridine compound and a methylpyridine derivative compound. In some examples, the slurry composition also includes an etching inhibitor. In some cases, the slurry composition may include an abrasive, a surfactant, an organic complexant, a chelating agent, an organic or inorganic acid, an organic or inorganic base, a corrosion inhibitor, or a buffer. The slurry composition may be distributed onto a surface of a polishing pad disposed on a platen that is configured to rotate. Additionally, a workpiece carrier configured to house a substrate may bring the substrate into contact with the rotating polishing pad and thereby polish the substrate utilizing the slurry composition.

Abstract: A sieve for microparticles includes a seat having a chamber and a plurality of boards mounted in the chamber. Each of the plurality of boards includes a first face and a second face opposite to the first face. The first face includes at least one notch. The second face includes at least one groove. The first face of each of the plurality of boards abuts the second face of an adjacent board. The at least one notch and the at least one groove respectively of two adjacent boards are partially aligned and intercommunicated with each other.

Abstract: A sieve for microparticles includes a seat having a chamber and a plurality of boards mounted in the chamber. Each of the plurality of boards includes a first face and a second face opposite to the first face. The first face includes at least one notch. The second face includes at least one groove. The first face of each of the plurality of boards abuts the second face of an adjacent board. The at least one notch and the at least one groove respectively of two adjacent boards are partially aligned and intercommunicated with each other.

Abstract: A CMP slurry composition which provides for a high Ge- or SiGe-to-dielectric material selectivity a low rate of Ge or SiGe recess formation includes an oxidant and a germanium removal rate enhancer including at least one of a methylpyridine compound and a methylpyridine derivative compound. In some examples, the slurry composition also includes an etching inhibitor. In some cases, the slurry composition may include an abrasive, a surfactant, an organic complexant, a chelating agent, an organic or inorganic acid, an organic or inorganic base, a corrosion inhibitor, or a buffer. The slurry composition may be distributed onto a surface of a polishing pad disposed on a platen that is configured to rotate. Additionally, a workpiece carrier configured to house a substrate may bring the substrate into contact with the rotating polishing pad and thereby polish the substrate utilizing the slurry composition.

Abstract: The present disclosure relates to a heating device and a biochemical reactor having the heating device. The heating device includes an upper plate, a lower plate, a middle plate, and an electric heating element. The upper plate has an upper heating hole, an upper receiving hole, and an upper conductive layer. The lower plate has a lower heating hole, a lower receiving hole, and a first lower conductive layer. The middle plate is disposed between the upper and lower plates and has a middle heating hole and a middle receiving hole. The upper, middle and lower receiving holes are connected together to form a receiving through hole. The electric heating element is disposed in the receiving through hole and has two terminals connected to the upper conductive layer and the lower conductive layer, respectively.

Abstract: The present disclosure relates to a method of performing a chemical mechanical planarization (CMP) process with a high germanium-to-oxide removal selectivity and a low rate of germanium recess formation. The method is performed by providing a semiconductor substrate having a plurality of germanium compound regions including germanium interspersed between a plurality of oxide regions including an oxide. A slurry is then provided onto the semiconductor substrate. The slurry has an oxidant and an etching inhibitor configured to reduce a removal rate of the germanium relative to the oxide. A CMP process is then performed by bringing a chemical mechanical polishing pad in contact with top surfaces of the plurality of germanium compound regions and the plurality of oxide regions.

Abstract: Provided is a slurry composition including abrasive particles, halogen oxide, and nitroxide compound. The combination of halogen oxide and nitroxide compound has a synergistic effect to remove a substrate containing tungsten and silicon oxide. Moreover, a use of the slurry composition and a polishing method using the slurry composition are provided.

Abstract: A biochemical reactor includes a temperature control device containing a substrate, a first conductive layer, a second conductive layer, a receiving hole, and a heating element. The substrate has a through hole for accommodating the vessel; the receiving hole is adjacent to the through hole for receiving the heating element; the first conductive layer has a connecting region formed on the wall of the through hole; and two terminals of the heating element are respectively connected electrically to the first and the second conductive layers. As such, the heat generated from the heating element can be transferred to the through hole via the first conductive layer to heat the vessel.