Abstract: The present invention provides compounds of Formula I: or pharmaceutically acceptable salts thereof, as well as their compositions and methods of use, that inhibit the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Abstract: The present disclosure provides for multi-specific antibodies and antigen-binding fragments thereof that bind to human MUC1 and CD16A, pharmaceutical compositions comprising said antibodies, and use of the antibodies or the compositions for treating a disease, such as cancer.

Abstract: Embodiments of a method and system for inversion of high-resolution aquifer storage coefficient based on gravity satellite data are disclosed. The method comprises: acquiring gravity satellite data, soil moisture storage data, surface water storage data and other non-groundwater component data, based on a preset region. The method also comprises: obtaining monthly time series of terrestrial water storage anomalies, by inversing the gravity satellite data; obtaining monthly time series of soil moisture storage anomalies, surface water storage anomalies, and other non-groundwater component anomalies; obtaining monthly time series of groundwater storage anomalies; and obtaining monthly time series of groundwater level anomalies in different aquifers.

Abstract: Disclosed are a heating control circuit and a heating equipment. The control module is respectively connected with the zero-crossing detection circuit, the thyristor switch circuit and the temperature control circuit. The time is preset in the control module. If the heating control circuit is powered off, it will be powered on again within the preset time as the signal collected by the zero-crossing detection circuit triggers the conduction of the thyristor switch circuit to start the heating component, and resume the heat preservation mode, by which the body memory function is implemented; even if the heating control circuit is not powered on again within the preset time after the heating control circuit is powered off, the water temperature is detected through the temperature control circuit to realize the water temperature memory function.

Abstract: An electric pot comprises a pot body, a pot lid rotatably connected to the pot lid, and a handle connected to the pot body. The electric pot further comprises a tea filtering net and a hanger connected to each other, a connecting block is provided at a pot spout of the pot body, a hanging groove cooperating with the hanger is provided on the connecting block, and the hanging groove is located in the pot body. When making tea, the tea filtering net loaded with tea leaves is buckled on a connecting block area inside the pot body via a hanger to be in full contact with hot water in the pot body; when filing or replacing tea, only the tea filtering net located in the pot body can be taken out without disassembling the pot lid, and there is no risk of loss of the pot lid.

Abstract: A storage box comprises a box body and a box lid. The box lid comprises a lid body and a first bent portion successively connected from the inside to the outside. The box body has a box opening. The lid body is provided at the box opening. A snap is provided on an inner side of the first bent portion near an edge. The box opening is provided with a second bent portion. The second bent portion is provided with a clamping groove matching the snap. A blocking ring is provided below the clamping groove. The blocking ring is provided along the edge of the box lid and protrudes outside the box lid. The storage box can effectively prevent the loss of the items stored in the storage box, avoid malicious damage to packaging, products, and other harmful behaviors, and effectively avoid property losses for users.

Abstract: Disclosed is a packaging box including a box body and a box lid, the box lid including a lid body and a first bent portion, the box body having a box opening, the box lid being provided at the box opening, where the box opening is provided with a second bent portion; when the box body and the box lid are closed and looking up the packaging box, a bottom end face of an outer side wall of the first bent portion is invisible; the box lid is provided with a first locked portion, the box body is provided with a second locked portion corresponding to a lower side of the first locked portion; and the lid body is provided with an inspection window. The packaging box solve the problem that the articles in the box would be missing and facilitate the personnel to inspect the articles within the box.

Abstract: The invention provides an automatic stop method and device for a can opener. When a first rotation frequency of a bearing in a first preset time is smaller than a second rotation frequency of the bearing in a subsequent second preset time in the process of opening a can by a can opener blade and a difference between the second and first frequency reaches a preset value, it is determined that repeated cutting occurs, and the blade will be stopped in time to avoid problems caused by repeated cutting. Meanwhile, mean values of multiple data acquired within the first and second preset time are calculated, avoiding the problems of an excessively high and long instant processing burden of one time of data acquisition and errors caused by data acquired once, improving the timeliness and accuracy of the first and second frequency, and can opening can be controlled more accurately.

Abstract: The application provides an air purifier comprising a shell assembly having air inlets and air outlets, and a filter assembly, an air inflow guide assembly, a fan and a diffusion air outflow assembly sequentially arranged from back to front. The filter assembly can purify air entering the filter assembly via the air inlets and flowing through the filter assembly. The air inflow guide assembly defines a guide channel between the filter assembly and the fan. The fan generates an air flow that flows into a first receiving cavity via the air inlets and sequentially flows through each assembly. The diffusion air outflow assembly can rotate to guide the air flow to the air outlets, enable the air flow to diffuse outwards and decrease the flow velocity of the air flow. The air purifier expands the purification range of the air purifier and improves the purification effect of the air purifier.

Abstract: A local activation method and system based on a binary neural network, said method including: during forward propagation, comparing the difference between a center pixel and an adjacent pixel to determine a local activation value; during forward propagation, setting an appropriate number of local activation channels and an activation direction to obtain a local activation feature map having different activation directions; during forward propagation, using weighting coefficients, which can be learned, to perform channel fusion on the output feature map after local activation and direct activation, and obtaining an output feature map containing both texture features and contour features; during backpropagation, using an asymptotic sine function to update the weights of the binary neural network.

Abstract: The present application discloses an electric cutter assembly, including a handle component and a blade component configured movably on the handle component, wherein the handle component is provided therein with a driving component for driving the blade component to reciprocate relative to the handle component and a storage battery electrically connected to the driving component, and the handle component is further provided with a charging interface electrically connected to the storage battery. The electric cutter assembly provided in the present application has the driving component powered with a built-in storage battery so that the handle component can drive the blade component to reciprocate and cut food materials without connecting to an external power source, which effectively avoids the hindrance of the power cord in the use of the electric cutter assembly, and the user can move the electric cutter assembly to any desired position to perform food material processing, which is convenient for the user.

Abstract: A multi-task deep learning network and a generation method thereof are provided. The generation method of a multi-task deep learning network includes: building at least one shared layer, where the shared layer is configured to receive a plurality of pieces of input information and generate a plurality of pieces of processed feature information; building a plurality of groups of task-specific layers, wherein the groups of task-specific layers compute and generate a plurality of groups of output information corresponding to a plurality of different tasks according to the pieces of processed feature information; and activating at least one of the groups of task-specific layers in stages according to a power supply state of an electronic apparatus.