Patents by Inventor Yun-Ping Zhou

Yun-Ping Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-TRP
    Patent number: 7087394
    Abstract: Expression of beta-TRP is enriched in islet cells. Introduction of expression cassettes encoding beta-TRP into diabetic islet cells improved glucose-stimulated insulin production.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: August 8, 2006
    Assignee: Metabolex, Inc.
    Inventors: Jeffrey D. Johnson, Yun-Ping Zhou
  • Compositions and methods of using apoptosis signaling kinase related kinase (ASKRK)
    Publication number: 20050233347
    Abstract: The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of ASKRK nucleic acids and proteins.
    Type: Application
    Filed: November 3, 2004
    Publication date: October 20, 2005
    Applicant: METABOLEX, INC.
    Inventors: Jeffrey Johnson, Yun-Ping Zhou, Kimberly Marlen
  • Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-TRP
    Publication number: 20040259160
    Abstract: Expression of beta-TRP is enriched in islet cells. Introduction of expression cassettes encoding beta-TRP into diabetic islet cells improved glucose-stimulated insulin production.
    Type: Application
    Filed: March 4, 2004
    Publication date: December 23, 2004
    Applicant: METABOLEX, INC.
    Inventors: Jeffrey D. Johnson, Yun-Ping Zhou
  • Methods and reagents for diagnosis and treatment of diabetes
    Publication number: 20030202976
    Abstract: The invention relates to methods and reagents for diagnosing and treating diabetes.
    Type: Application
    Filed: December 2, 2002
    Publication date: October 30, 2003
    Applicant: METABOLEX, INC.
    Inventors: Jeffrey D. Johnson, John E. Blume, John F. Palma, Yun-Ping Zhou
  • Methods of treatment of type 2 diabetes
    Publication number: 20020150896
    Abstract: The present invention relates generally to the field of diabetes. More particularly, it concerns the identification of genes responsible for NIDDM1 for use in diagnostic and therapeutic applications. The present invention demonstrates that the NIDDM1 locus is, in fact, the calpain 10 gene. The invention further relates to the discovery that analysis of mutations in calpain genes and gene products can be diagnostic for type 2 diabetes. The invention also contemplates methods of treating diabetes in view of the fact that calpain mutations can cause diabetes. Further, the invention relates to novel polynucleotides of the NIDDM1 locus and polypeptides encoded by such polynucleotides.
    Type: Application
    Filed: January 23, 2001
    Publication date: October 17, 2002
    Applicant: Board of Regents, The University of Texas System
    Inventors: Kenneth S. Polonsky, Yukio Horikawa, Naohisa Oda, Nancy J. Cox, Kenichi Otani, Craig L. Hanis, Graeme I. Bell, Seamus Kevin Sreenan, Yun-Ping Zhou