Abstract: A method of patterning an underlying structure includes the following. A first patterning process is performed on the underlying structure to form a first patterned underlying structure including a first opening. A patterned photoresist layer is formed, and the patterned photoresist layer fills the first opening. A second patterning process is performed on the first patterned underlying structure to form a second patterned underlying structure including the first opening and a second opening.

Abstract: A polyurethane insulation foam composition is disclosed herein. The polyurethane insulation foam comprises: (i) an aromatic isocyanate compound; (ii) an isocyanate reactive compound; (iii) water; (iv) a tertiary amine compound; (v) a hydrophilic carboxylic acid compound; (vi) a halogenated olefin compound; (vii) a stabilizing compound, and (vii) optionally, other additives.

Abstract: A crystal form and salt form of a bromine domain protein inhibitor represented by formula (I), a preparation method therefor, and a use of the crystal form and salt form in the preparation of a drug for treating diseases mediated by BET protein.

Abstract: A display panel includes a first substrate, pixel structures, a first common pad, a second substrate, a second common electrode, a display medium and a conductive particle. The pixel structures are disposed on an active area of the first substrate. The first common pad is disposed on a peripheral area of the first substrate, and is electrically connected to first common electrodes of the pixel structures. The second common electrode is disposed on the second substrate. The conductive particle is disposed on the first common pad, and is electrically connected to the first common pad and the second common electrode. The conductive particle includes a core and a conductive film disposed on a surface of the core, where the conductive film has a main portion and raised portions, and a film thickness of each of the raised portions is greater than a film thickness of the main portion.

Abstract: An anti-tipping oral hygiene instrument exchanging structure includes a handle member attachable to a base member that includes a weight element, a circular curved section formed on the weight element, a base engaging section formed on the weight element, and a plurality of placing sections formed on the base member. The circular curved section is used in combination with the weight element to prevent the handle member from tipping over. The handle member has a handle engaging portion combinable with one hygiene piece. The hygiene piece includes a mutual engaging section mountable to the handle engaging portion in order to achieve an advantage of fast replacement. The hygiene piece includes a first rod, a plurality of holed sections formed on the first rod, and a plurality of detaching sections formed on the holed sections to provide an effect of assisting the operation and use of floss.

Abstract: There is provided a method of identifying/characterising coronavirus infection in a human subject. In a specific embodiment the method comprising contacting a serum sample from the subject with an isolated host cell expressing a nucleotide that encodes for a codon optimised gene for SARS-CoV-2 spike protein (S protein); and detecting a binding of an antibody or an antigen-binding fragment thereof to said host cell using a flow cytometry and a labelled anti-human secondary antibody. Also disclosed is a method of identifying a subject having immunity for coronavirus, especially SARS-CoV-2 wherein a sample from a subject is incubated with said cell and is detected using the flow cytometry and the labelled anti-human secondary antibody. Nucleic acid encoding a SARS-CoV-2 S protein, viral vectors and host cells thereof are also disclosed.

Abstract: A method is provided. An actual fatigue curve limit is determined for actual stress of a drilling component based on an actual yield strength of a material of the drilling component. A plurality of drilling parameters is simulated for the drilling component to determine one or more estimated stresses enacted on the drilling component for one or more combinations of the plurality of drilling parameters. A component life cycle of the drilling component is determined based on the actual fatigue curve limit and the plurality of drilling parameters. A consumed component life of the drilling component is determined for an actual drilling step utilizing the drilling component, and a remaining life of the drilling component after the actual drilling step is determined.

Abstract: An anode active material of a lithium-ion battery is provided. The active material of the anode of the lithium-ion battery includes silicon, tin and copper-zinc alloy, in which tin is substantially in an elemental state. Moreover, an anode of a lithium-ion battery is provided. The anode of the lithium-ion battery includes the active material as mentioned above.

Abstract: An electrostatic chuck is provided, the electrostatic chuck includes a base; and an insulating layer, an electrode layer, a first dielectric layer, and a second dielectric layer sequentially stacked on the base. The first dielectric layer is aluminum oxide (Al2O3) or aluminum nitride (AlN). A material of the second dielectric layer is different from a material of the first dielectric layer, and the second dielectric layer includes titanium element, IVA group element, and oxygen element.

Abstract: The present invention relates to certain compositions of a 5-HT2A serotonin receptor modulator and methods for their preparation. The compositions disclosed herein are useful for increasing slow wave sleep, improving sleep consolidation, improving sleep maintenance and improving sleep quality, and for treating insomnia and related sleep disorders, dyssomnias, parasomnias and nonrestorative sleep and the like.

Abstract: A polyurethane insulation foam composition is disclosed herein. The polyurethane insulation foam comprises: (i) an aromatic isocyanate compound; (ii) an isocyanate reactive compound; (iii) water; (iv) a tertiary amine compound; (v) a hydrophilic carboxylic acid compound; (vi) a halogenated olefin compound; (vii) a stabilizing compound, and (vii) optionally, other additives.

Abstract: A storage module of distributed flow battery is provided. An electrochemical reaction is processed with the positive and negative electrolytes to produce and/or discharge direct current and further output the positive and negative electrolytes after the reaction. The module comprises two end plates; two frames disposed between the two end plates; two current collectors disposed between the two frames; two complex cast polar plates disposed between the two current collectors; two electrodes disposed between the two complex cast polar plates; a membrane disposed between the two electrodes; and three gaskets. Therein, two of the gaskets are set to sandwich and enclose one of the two complex cast polar plates; and the other one of the gaskets is set between the other one of the two complex cast polar plates and an adjacent one of the current collectors.

Abstract: A method for manufacturing a water-based coating material is provided, including: (a) reacting tetraalkoxysilane, acidic aqueous solution of vanadium salt, and trialkoxyalkylsilane to form an oligomer; (b) reacting the oligomer with colloidal silica particles to form a modified oligomer; and (c) reacting the modified oligomer with trialkoxyepoxysilane to obtain a water-based coating material.

Abstract: An anode active material of a lithium ion battery includes primary particles. The primary particles include Si, Sn and Sb. The primary particles have peaks at X-ray diffraction 2? position of 29.1±1°, 41.6±1°, 51.6±1°, 60.4±1°, 68.5±1°, and 76.1±1°.

Abstract: A storage module of distributed flow battery is provided. An electrochemical reaction is processed with the positive and negative electrolytes to produce and/or discharge direct current and further output the positive and negative electrolytes after the reaction. The module comprises two end plates; two frames disposed between the two end plates; two current collectors disposed between the two frames; two complex cast polar plates disposed between the two current collectors; two electrodes disposed between the two complex cast polar plates; a membrane disposed between the two electrodes; and three gaskets. Therein, two of the gaskets are set to sandwich and enclose one of the two complex cast polar plates; and the other one of the gaskets is set between the other one of the two complex cast polar plates and an adjacent one of the current collectors.

Abstract: The present invention relates to certain compositions of a 5-HT2A serotonin receptor modulator and methods for their preparation. The compositions disclosed herein are useful for increasing slow wave sleep, improving sleep consolidation, improving sleep maintenance and improving sleep quality, and for treating insomnia and related sleep disorders, dyssomnias, parasomnias and nonrestorative sleep and the like.

Abstract: An anode active material of a lithium-ion battery is provided. The active material of the anode of the lithium-ion battery includes silicon, tin and copper-zinc alloy, in which tin is substantially in an elemental state. Moreover, an anode of a lithium-ion battery is provided. The anode of the lithium-ion battery includes the active material as mentioned above.

Abstract: An anti-tipping oral hygiene instrument exchanging structure includes a handle member attachable to a base member that includes a weight element, a circular curved section formed on the weight element, a base engaging section formed on the weight element, and a plurality of placing sections formed on the base member. The circular curved section is used in combination with the weight element to prevent the handle member from tipping over. The handle member has a handle engaging portion combinable with one hygiene piece. The hygiene piece includes a mutual engaging section mountable to the handle engaging portion in order to achieve an advantage of fast replacement. The hygiene piece includes a first rod, a plurality of holed sections formed on the first rod, and a plurality of detaching sections formed on the holed sections to provide an effect of assisting the operation and use of floss.

Abstract: A method is provided. An actual fatigue curve limit is determined for actual stress of a drilling component based on an actual yield strength of a material of the drilling component. A plurality of drilling parameters is simulated for the drilling component to determine one or more estimated stresses enacted on the drilling component for one or more combinations of the plurality of drilling parameters. A component life cycle of the drilling component is determined based on the actual fatigue curve limit and the plurality of drilling parameters. A consumed component life of the drilling component is determined for an actual drilling step utilizing the drilling component, and a remaining life of the drilling component after the actual drilling step is determined.

Abstract: A method for remotely updating firmware of a field programmable gate array (FPGA) includes: by a controller, transmitting a storing instruction and relaying an entry of configuration data received from a remote device to a processor of the FPGA; by the processor, performing an updating subtask to store a file segment recorded in the entry of configuration data in an update-storage area indicated by location information recorded in the entry of configuration data; by the controller, determining whether the processor has successfully completed the updating subtask, and when affirmative, enabling the remote device to transmit another entry of configuration data; and repeating the aforementioned steps.