Abstract: Disclosed is a composition having a substrate comprising metal oxide particles. The substrate has a coating thereon that includes an organic dispersant present in a amount that renders the substrate self-dispersible. Also disclosed is a composition, such as a cosmetic composition, that includes that self-dispersible coated substrate, and a process that includes coating a particulate metal oxide with an organic dispersant to render the metal oxide self dispersible.

Abstract: Disclosed is a composition that comprises an effective proportion of a first metal oxide powder having a primary particle size and a secondary particle size selected for the first metal oxide powder to attenuate UV A and an effective proportion of a second metal oxide powder having a secondary particle size selected for the second metal oxide powder to attenuate UVB. The mean secondary particle size of the first metal oxide powder is greater than the mean secondary particle size of the second metal oxide powder. In one embodiment, the first and the second metal oxide powders are both zinc oxide.

Abstract: This disclosure provides sunscreen products that contain metal oxide powders having discrete size distributions. Metal oxide powders include, for example, zinc oxide and titanium dioxide. Sunscreen products made in accordance with the principles of this disclosure contain metal oxide powders having primary particle sizes of about 10-30 nm and about 50-200 nm.

Abstract: Disclosed is a composition having a substrate comprising metal oxide particles. The substrate has a coating thereon that includes an organic dispersant present in a amount that renders the substrate self-dispersible. Also disclosed is a composition, such as a cosmetic composition, that includes that self-dispersible coated substrate, and a process that includes coating a particulate metal oxide with an organic dispersant to render the metal oxide self dispersible.

Abstract: This application discloses an aqueous dispersion of waxes, polymers, pigments and other functional additives, which can be used as a concentrate of an eye make-up composition. The dispersion contains about 70% solids and can be diluted at room temperature and adjusted with additional ingredients if desired, which enables commercial cosmetic manufacturers to develop and manufacture new formulations with the minimal effort and cost.

Abstract: A wax-resin composite is made by melting thermoplastic hydrocarbon resin, optionally with an antioxidant. The melted thermoplastic hydrocarbon resin and waxes are blended at a temperature sufficient to melt the waxes. After blending and melting, the blended thermoplastic hydrocarbon resin and waxes are allowed to solidify. Solidification is followed by post-processing the wax-resin composite mixture to form slabs, pastilles, flakes or other forms. A method for producing a wax-resin composite comprises at least partially solvating a thermoplastic resin in a solvent to form a resin-solvent blend. This may be done at a heat of 80-85° C. A composition of molten wax is blended with the resin-solvent blend. The resin-solvent blend and a molten wax are blended to form a wax-resin blend. This is followed by removing the solvent from said wax-resin blend.

Abstract: Disclosed is a composition having a substrate comprising metal oxide particles. The substrate has a coating thereon that includes an organic dispersant present in a amount that renders the substrate self-dispersible. Also disclosed is a composition, such as a cosmetic composition, that includes that self-dispersible coated substrate, and a process that includes coating a particulate metal oxide with an organic dispersant to render the metal oxide self-dispersible.

Abstract: This disclosure provides sunscreen products that contain metal oxide powders having discrete size distributions. Metal oxide powders include, for example, zinc oxide and titanium dioxide. Sunscreen products made in accordance with the principles of this disclosure contain metal oxide powders having primary particle sizes of about 10-30 ran and about 50-200 nm.

Abstract: The present invention relates to a vaccine composition against the infection of human respiratory syncytial virus (RSV) comprising a replication-defective recombinant adenovirus carrying a nucleotide sequence encoding the F protein of RSV or fragment thereof. A method of preventing RSV infection-related diseases using the vaccine composition of the present invention is also provided.

Abstract: Disclosed is a composition that comprises an effective proportion of a first metal oxide powder having a primary particle size and a secondary particle size selected for the first metal oxide powder to attenuate UVA and an effective proportion of a second metal oxide powder having a secondary particle size selected for the second metal oxide powder to attenuate UVB. The mean secondary particle size of the first metal oxide powder is greater than the mean secondary particle size of the second metal oxide powder. In one embodiment, the first and the second metal oxide powders are both zinc oxide.

Abstract: A macroparticle pigment powder and methods of making the same. The macroparticle pigment powder comprises a plurality of macroparticle particles. The macroparticles are comprised of a matrix material that include pigment particles. In some embodiments the matrix material is polymeric in nature and selected from the group consisting of a natural latex, acrylics, polyacrylate, polymethacrylate, polyurethane, polyvinyl acetate, styrene-butadiene rubber, acrylonitrile butadiene styrene copolymer, and combinations thereof.

Abstract: The present invention is directed to processes for preparing a pyridyl piperidine compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.

Abstract: The present invention provides UV attenuating nanoparticles entrapped in porous particulates that are coated with a wax material. The porous particulates also include a fatty acid applied to the wax coating. Also provided is a method of producing a powder comprised of UV attenuating nanoparticles entrapped in porous particulates coated with a wax material. Further provided is a composition, such as a cosmetic composition, which includes the porous particulates loaded with the UV attenuating nanoparticles.

Abstract: A wax-resin composite is made by melting thermoplastic hydrocarbon resin, optionally with an antioxidant. The melted thermoplastic hydrocarbon resin and waxes are blended at a temperature sufficient to melt the waxes. After blending and melting, the blended thermoplastic hydrocarbon resin and waxes are allowed to solidify. Solidification is followed by post-processing the wax-resin composite mixture to form slabs, pastilles, flakes or other forms. A method for producing a wax-resin composite comprises at least partially solvating a thermoplastic resin in a solvent to form a resin-solvent blend. This may be done at a heat of 80-85° C. A composition of molten wax is blended with the resin-solvent blend. The resin-solvent blend and a molten wax are blended to form a wax-resin blend. This is followed by removing the solvent from said wax-resin blend.

Abstract: The present invention provides compositions for natural cosmetic products and, more particularly, to natural ester, wax or oil treated pigments, the products of such treated pigments and cosmetic products incorporating pigments treated with natural ingredients.

Abstract: A wax-resin composite is made by melting thermoplastic hydrocarbon resin, optionally with an antioxidant. The melted thermoplastic hydrocarbon resin and waxes are blended at a temperature sufficient to melt the waxes. After blending and melting, the blended thermoplastic hydrocarbon resin and waxes are allowed to solidify. Solidification is followed by post-processing the wax-resin composite mixture to form slabs, pastilles, flakes or other forms. A method for producing a wax-resin composite comprises at least partially solvating a thermoplastic resin in a solvent to form a resin-solvent blend. This may be done at a heat of 80-85° C. A composition of molten wax is blended with the resin-solvent blend. The resin-solvent blend and a molten wax are blended to form a wax-resin blend. This is followed by removing the solvent from said wax-resin blend.

Abstract: Computer-implemented techniques are disclosed for verifying functional independence of logic designs that make use of redundant representations. Initially, the design of a logic component is obtained. Two representations of the component are computed, one in redundant form and another in non-redundant form. A randomness factor based on a time-varying value is injected into the second representation. The value from the second form is then constrained to the context of the logic component within a digital system. It is then possible to analyze the component using the first deterministic representation and the constrained second representation. This analysis allows verification of the component with downstream logic.

Abstract: Computer-implemented techniques are disclosed for verifying functional independence of logic designs that make use of redundant representations. Initially, the design of a logic component is obtained. Two representations of the component are computed, one in redundant form and another in non-redundant form. A randomness factor based on a time-varying value is injected into the second representation. The value from the second form is then constrained to the context of the logic component within a digital system. It is then possible to analyze the component using the first deterministic representation and the constrained second representation. This analysis allows verification of the component with downstream logic.

Abstract: The present invention provides compositions for natural cosmetic products and, more particularly, to natural ester, wax or oil treated pigments, the products of such treated pigments and cosmetic products incorporating pigments treated with natural ingredients.

Abstract: The present invention is directed to processes for preparing a pyridyl piperidine compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.