Patents by Inventor Yun Xia

Yun Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250064029
    Abstract: Disclosed are a device and a method for nitrogen and phosphorus removal from aquaculture tail water based on agricultural waste filler, and belongs to the technical field of aquaculture tail water treatment. The device includes a device main body, and a reaction part is arranged in the device main body; a bottom end of the device main body is communicated with an aquaculture tail water storage pool, and a top side wall of the device main body is communicated with an effluent collection pool; and the reaction part comprises agricultural waste filler and denitrifying sludge contained in the device main body, and the agricultural waste filler and the denitrifying sludge are soaked in the aquaculture tail water.
    Type: Application
    Filed: August 1, 2024
    Publication date: February 27, 2025
    Inventors: Wangbao GONG, Jun XIE, Guangjun WANG, Zhifei LI, Kai ZHANG, Zhilong WANG, Yun XIA, Hongyan LI, Jingjing TIAN, Wenping XIE
  • Publication number: 20240120030
    Abstract: The present application provides a method for analyzing droplets on the basis of volume distribution including obtaining a total volume V of a sample containing target molecules based on a system prepared using the sample. The system is emulsified into droplets. A droplet system is obtained when the droplets obtaining the sample executes an amplification reaction. A droplet image of the droplet system is obtained. A total number n of droplets included in the droplet system is obtained based on the droplet image. A droplet volume distribution of the droplet system is obtained based on the droplet image. A number j of negative droplets among the n droplets is counted. A quantitative analysis is performed for the target molecules according to the total volume V of the sample, the total number n of droplets, the droplet volume distribution information, and the number j of negative droplets.
    Type: Application
    Filed: January 13, 2021
    Publication date: April 11, 2024
    Inventors: YUN XIA, XIA ZHAO, YANG XI, YI WEI, FANG CHEN, HUI JIANG
  • Publication number: 20230342978
    Abstract: A method for analyzing droplets based on images: obtaining a working dye channel image and a reference dye channel image corresponding to a droplet system (S1); separately performing a preset image processing operation on the working dye channel image and the reference dye channel image (S2); using the working dye channel image or the reference dye channel image as a target image (S3), and determining a region in which each droplet is located from within the target image (S4); and on the basis of the determined region in which each droplet is located, analyzing the droplet system (S5). The method can effective effectively improve the accuracy of droplet analysis. Further provided are a computer device and a storage medium.
    Type: Application
    Filed: February 14, 2020
    Publication date: October 26, 2023
    Inventors: YUN XIA, YANG XI, XIA ZHAO, XINGYE CUI, HANJIE SHEN, FANG CHEN, HUI JIANG
  • Publication number: 20230311125
    Abstract: A flow cell includes a first cover; a second cover facing the first cover, and at least two spacers provided side by side between the first cover and the second cover. The first cover, the second cover, and two adjacent spacers cooperatively form a flow path, surface of the first cover near the second cover piece forms a detection surface. A first opening is provided at an end of the flow path, which can inject a first sample into the flow path. The first sample is adsorbed on the detection surface. A second opening is provided at another end of the flow path, which can inject microdroplets into the flow path. The microdroplets include a second sample. A liquid inlet and outlet device applying flow cell and a sample analysis system are further provided.
    Type: Application
    Filed: September 4, 2020
    Publication date: October 5, 2023
    Inventors: XINGYE CUI, CHUTIAN XING, YUN XIA, YANG XI
  • Publication number: 20220411858
    Abstract: A random emulsification digital absolute quantitative analysis method includes: performing random emulsification processing on a system to be emulsified to obtain several isolated reaction zones or droplets; determining the total number and volume information of the various reaction zones or droplets, the presence of target molecules to be tested in the respective reaction zones or droplets, and the number of reaction zones or droplets which do not contain the target molecules by combining acquired target images comprising image regions corresponding to the amplified reaction zones or droplets, and analyzing the target images; and accurately calculating the volume information of the various reaction zones or droplets, the presence of the target molecules to be tested in the respective reaction zones or droplets, and the number of reaction zones or droplets which do not contain the target molecules, the total number of target molecules in a sample to be tested.
    Type: Application
    Filed: November 29, 2019
    Publication date: December 29, 2022
    Applicant: MGI TECH CO., LTD.
    Inventors: Yun Xia, Xia Zhao, Yang Xi, Fang Chen, Hui Jiang
  • Publication number: 20220387584
    Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate pathway as an adjutant.
    Type: Application
    Filed: May 19, 2022
    Publication date: December 8, 2022
    Applicant: Tsinghua University
    Inventors: Yonghui Zhang, Yun Xia, Yonghua Xie, Zhengsen Yu, Xiaoying Zhou, Xin Li, Liping Li, Yunyun Yang, Kanzhao Gao, Ke Wang, Wanli Liu, Meng Zhao
  • Patent number: 11382971
    Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate pathway as an adjuvant.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: July 12, 2022
    Assignee: Tsinghua University
    Inventors: Yonghui Zhang, Yun Xia, Yonghua Xie, Zhengsen Yu, Xiaoying Zhou, Xin Li, Liping Li, Yunyun Yang, Kanzhao Gao, Ke Wang, Wanli Liu, Meng Zhao
  • Publication number: 20210008084
    Abstract: Provided in the present invention is the use of a mevalonic acid pathway inhibitor in the preparation of a drug for treating and/or preventing tumours, inducing immunogenic death of tumour cells, inducing immune responses and activating T cells or DC cells to directly promote host immunity. Also provided in the present invention is a pharmaceutical composition comprising the mevalonic acid pathway inhibitor and an antitumour drug (for example, an immune checkpoint inhibitor and any drug that can lead to new antigen production) and a combination of the mevalonic acid pathway inhibitor and an antitumour drug (for example, an immune checkpoint inhibitor and any drug that can lead to new antigen production) and/or the radiotherapy.
    Type: Application
    Filed: October 15, 2018
    Publication date: January 14, 2021
    Applicant: TSINGHUA UNIVERSITY
    Inventors: Yonghui ZHANG, Xiaoying ZHOU, Hongying XIAO, Yun XIA, Yonghua XIE, Zhengsen YU
  • Publication number: 20200410474
    Abstract: This disclosure relates to account transfer request processing. In one aspect, a method includes obtaining an account transfer request submitted by a first terminal. The account transfer request is a request to transfer a transfer amount from the account of the initiator to a payee. Payee information corresponding to the payee of the account transfer request is obtained. The payee information includes identification information specifying payee contact information for the payee. A determination is made that the payee is not a registered user of a platform that initiated the account transfer request. This determination includes querying whether the identification information exists in a registered user database of the platform. In response to determining that the payee is not a registered user of the platform, a payment prompt that is configured to prompt the payee to collect payment of the account transfer is transmitted to a second terminal of the payee.
    Type: Application
    Filed: May 18, 2020
    Publication date: December 31, 2020
    Inventors: Yun Xia, Zunfu Dai, Fan Yang
  • Publication number: 20190321465
    Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate to pathway as an adjuvant.
    Type: Application
    Filed: September 8, 2016
    Publication date: October 24, 2019
    Applicants: Tsinghua University, Tsinghua University
    Inventors: Yonghui Zhang, Yun Xia, Yonghua Xie, Zhengsen Yu, Xiaoying Zhou, Xin Li, Liping Li, Yunyun Yang, Kanzhao Gao, Ke Wang, Wanli Liu, Meng Zhao
  • Patent number: 10372427
    Abstract: A method according to one embodiment includes importing a plurality of resources associated with an entity, receiving, from the entity, a request for an application that performs predetermined functionality, creating a functionality definition, utilizing the request, determining, from the plurality of resources associated with the entity, one or more necessary resources for implementing the functionality definition, constructing the application that performs the predetermined functionality, utilizing the one or more necessary resources, and implementing the application in an environment of the entity.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: August 6, 2019
    Assignee: HYDATA
    Inventors: Yicun Feng, Bai Yang, Yun Xia, Cheng Liu, Longhui Li, Yujie Zhang, Yuan Fan, Yi Xu
  • Publication number: 20190155584
    Abstract: A method according to one embodiment includes importing a plurality of resources associated with an entity, receiving, from the entity, a request for an application that performs predetermined functionality, creating a functionality definition, utilizing the request, determining, from the plurality of resources associated with the entity, one or more necessary resources for implementing the functionality definition, constructing the application that performs the predetermined functionality, utilizing the one or more necessary resources, and implementing the application in an environment of the entity.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 23, 2019
    Inventors: Yicun Feng, Bai Yang, Yun Xia, Cheng Liu, Longhui Li, Yujie Zhang, Yuan Fan, Yi Xu
  • Publication number: 20180320169
    Abstract: Provided is a method for constructing a DNA library for sequencing. The method comprises A-tailing of a single 3? end to at least a portion of blunt-end DNA fragments, and a step of blunt-end ligating the obtained DNA fragments having A tailing to the single 3? end. Also provided are a DNA library for sequencing constructed with the method and a corresponding sequencing method.
    Type: Application
    Filed: November 17, 2015
    Publication date: November 8, 2018
    Applicants: NANJING ANNOROAD GENE TECHNOLOGY CO. LTD, ANNOROAD GENE TECHNOLOGY (BEIJING) CO., LTD
    Inventors: Chongjian CHEN, Yun XIA, Qiongfang PENG, Zhandong WANG, Yuehan XUE, Zhaoling XUAN, Dawei LI, Junbin LIANG
  • Patent number: 10017829
    Abstract: Various methods and compositions are provided for identifying and/or selecting soybean plants or soybean germplasm with improved resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In certain embodiments, the method comprises detecting at least one marker locus that is associated with resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In other embodiments, the method further comprises detecting at least one marker profile or haplotype associated with resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In further embodiments, the method comprises crossing a selected soybean plant with a second soybean plant. Further provided are markers, primers, probes and kits useful for identifying and/or selecting soybean plants or soybean germplasm with improved resistance to Frogeye Leaf Spot and/or Brown Stem Rot.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: July 10, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Martin A. Fabrizius, Feng Han, Donald Kyle, Joshua M. Shendelman, Jordan D. Spear, Paul A. Stephens, Yun Xia
  • Patent number: 9994769
    Abstract: A liquid crystal composition having one or more compounds shown as formula I and one or more compounds shown as formula II, and the liquid crystal composition comprising a compound shown as formula II-A: wherein substituents are all defined. The composition has a low viscosity ?1, a moderate dielectric anisotropy ?? and a moderate optical anisotropy ?n, and can achieve fast response of a liquid crystal display.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: June 12, 2018
    Assignee: SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD.
    Inventors: GuoLiang Yun, Kui Wang, Yun Xia Qiao, Wei Wang, Yan Li Dong
  • Publication number: 20170015906
    Abstract: The present invention provides a liquid crystal composition, comprising one or more compounds shown as formula I and one or more compounds shown as formula II, and the liquid crystal composition comprising a compound shown as formula II-A: wherein substituents are all defined. The composition provided by the present invention has a low viscosity ?1, a moderate dielectric anisotropy ?? and a moderate optical anisotropy ?n, and can achieve fast response of a liquid crystal display.
    Type: Application
    Filed: May 26, 2016
    Publication date: January 19, 2017
    Inventors: GuoLiang YUN, Kui WANG, Yun Xia QIAO, Wei WANG, Yan Li DONG
  • Patent number: 9404038
    Abstract: The present invention is directed to compounds of the following General Formula I. The cyclopropyl-bearing liquid crystal compounds of Formula I of the present invention have a positive or negative dielectric anisotropy (??), an appropriate optical anisotropy (?n), an appropriate clearing point (CP), good low-temperature miscibility with other liquid crystals, a low rotary viscosity, and good UV stability and high-temperature thermal stability, and therefore have good use value. The compounds of the present invention can be used for preparing positive and negative liquid crystal compositions and can also be employed in passive and active matrix displays.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 2, 2016
    Assignee: Shijiazhuang Chengzhi Yonghua Display Materials Co., Ltd.
    Inventors: Guoliang Yuan, Jia Deng, Ming Li, Hu-bo Zhang, Yun-xia Qiao, Jin-song Meng, Rui-mao Hua
  • Publication number: 20160168461
    Abstract: The present invention is directed to compounds of the following General Formula I. The cyclopropyl-bearing liquid crystal compounds of Formula I of the present invention have a positive or negative dielectric anisotropy (??), an appropriate optical anisotropy (?n), an appropriate clearing point (CP), good low-temperature miscibility with other liquid crystals, a low rotary viscosity, and good UV stability and high-temperature thermal stability, and therefore have good use value. The compounds of the present invention can be used for preparing positive and negative liquid crystal compositions and can also be employed in passive and active matrix displays.
    Type: Application
    Filed: May 22, 2015
    Publication date: June 16, 2016
    Inventors: Guoliang Yuan, Jia Deng, Ming Li, Hu-bo Zhang, Yun-xia Qiao, Jin-song Meng, Rui-mao Hua
  • Publication number: 20160032409
    Abstract: Various methods and compositions are provided for identifying and/or selecting soybean plants or soybean germplasm with improved resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In certain embodiments, the method comprises detecting at least one marker locus that is associated with resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In other embodiments, the method further comprises detecting at least one marker profile or haplotype associated with resistance to Frogeye Leaf Spot and/or Brown Stem Rot. In further embodiments, the method comprises crossing a selected soybean plant with a second soybean plant. Further provided are markers, primers, probes and kits useful for identifying and/or selecting soybean plants or soybean germplasm with improved resistance to Frogeye Leaf Spot and/or Brown Stem Rot.
    Type: Application
    Filed: March 10, 2014
    Publication date: February 4, 2016
    Inventors: Martin A. Fabrizius, Feng Han, Donald Kyle, Joshua M. Shendelman, Jordan D. Spear, Paul A. Stephens, Yun Xia
  • Publication number: 20160034003
    Abstract: An electronic device includes a housing, a buffer layer, a display, and a printed circuit board. The housing includes a main body with a front side having an outer peripheral edge and a first surface and a peripheral side extending from the outer peripheral edge of the front side. The front side and the peripheral side cooperate to form a receiving recess with the first surface of the front side facing the receiving recess. The buffering layer is positioned on a portion of the first surface. The display is received into the receiving recess. The printed circuit board is received into the receiving recess and coupled to the display. The buffering layer includes elastic material and conductive material. The buffering layer is positioned between the first surface and the display.
    Type: Application
    Filed: December 1, 2014
    Publication date: February 4, 2016
    Inventors: NAI-LIN YANG, BING ZHANG, HAN-YUN XIA, SHI-FENG WANG