Patents by Inventor Yun Zou
Yun Zou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12135315Abstract: The present invention relates to a method for analyzing a metalloprotein in a biological sample capable of continuously maintaining conditions of LC-ICPMS constant to measure a metalloprotein with high data reliability. The method for analyzing a metalloprotein which is a complex in a biological sample, the metalloprotein being a complex in which a biomolecule and a metal element bind to each other, includes: treating a biological sample which has been subjected to a pretreatment by liquid chromatography to separate the metalloprotein, and analyzing the separated metalloprotein by inductively coupled plasma mass spectrometry, wherein an ammonium acetate solution is used as a mobile phase.Type: GrantFiled: April 12, 2019Date of Patent: November 5, 2024Assignee: SHIMADZU CORPORATIONInventors: Satoshi Yamaki, Yun Zou
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Patent number: 12116382Abstract: Embodiments of the present application relate to functionalized N-acetylgalactosamine analogs, methods of making, and uses of the same. In particular, polyvalent N-acetylgalactosamine analogs may be prepared by utilizing a wide variety of linkers containing functional groups. These functionalized N-acetylgalactosamine analogs may be used in the preparation of targeted delivery of oligonucleotide-based therapeutics.Type: GrantFiled: November 27, 2023Date of Patent: October 15, 2024Assignee: Hongene Biotech CorporationInventors: Wing C. Poon, Gang Zhao, Gengyu Du, Yun-Chiao Yao, Ruiming Zou, Aldrich N. K. Lau, David Yu, Guijun Yu, Zhixia Li
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Publication number: 20240336312Abstract: A biomimetic tower climbing robot and a tower climbing method thereof are provided. The robot mainly includes a main control body module and clamping and moving mechanism modules; two ends of the main control body module are connected to one clamping and moving mechanism module through an elastic universal joint respectively, two clamping and moving mechanism modules can alternately lock and unlock an anti-fall track of an iron tower, and the main control body module alternately pushes the clamping and moving mechanism module at its upper end upwards and pulls the clamping and moving mechanism module at its lower end upwards to achieve climbing of the robot along the anti-fall track.Type: ApplicationFiled: August 9, 2022Publication date: October 10, 2024Applicants: STATE GRID HUNAN ELECTRIC POWER COMPANY, STATE GRID HUNAN EXTRA HIGH VOLTAGE TRANSMISSION COMPANY, STATE GRID CORPORATION OF CHINAInventors: Jian ZHANG, Dehua ZOU, Dun MAO, Zhipeng JIANG, Zhiqiang HE, Zhengxiong GONG, Qiping DUAN, Bangwei LUO, Shuwen XIAO, Yun XIANG, Bocheng LI, Jie HE, Chonggen MO
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Patent number: 12098371Abstract: Embodiments of the present disclosure relate to lipid-PEGylated solid support and phosphoramidites derivatives, methods for preparing the same, and their uses in the delivery of oligonucleotide drugs to the cellular targets.Type: GrantFiled: August 16, 2023Date of Patent: September 24, 2024Assignee: Hongene Biotech CorporationInventors: Mufa Zou, David Yu, Aldrich N. K. Lau, Ruiming Zou, Wing C. Poon, Gang Zhao, Gengyu Du, Yun-Chiao Yao, Allen Wong, Xiaojun Li
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Patent number: 12091111Abstract: A biomimetic tower climbing robot and a tower climbing method thereof are provided. The robot mainly includes a main control body module and clamping and moving mechanism modules; two ends of the main control body module are connected to one clamping and moving mechanism module through an elastic universal joint respectively, two clamping and moving mechanism modules can alternately lock and unlock an anti-fall track of an iron tower, and the main control body module alternately pushes the clamping and moving mechanism module at its upper end upwards and pulls the clamping and moving mechanism module at its lower end upwards to achieve climbing of the robot along the anti-fall track.Type: GrantFiled: August 9, 2022Date of Patent: September 17, 2024Assignees: STATE GRID HUNAN ELECTRIC POWER COMPANY, STATE GRID HUNAN EXTRA HIGH VOLTAGE TRANSMISSION COMPANY, STATE GRID CORPORATION OF CHINAInventors: Jian Zhang, Dehua Zou, Dun Mao, Zhipeng Jiang, Zhiqiang He, Zhengxiong Gong, Qiping Duan, Bangwei Luo, Shuwen Xiao, Yun Xiang, Bocheng Li, Jie He, Chonggen Mo
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Publication number: 20240287120Abstract: Embodiments of the present application relate to functionalized N-acetylgalactosamine-analogs, methods of making, and uses of the same. In particular, mono or trivalent N-acetylgalactosamine analogs may be prepared by utilizing a wide variety of linkers containing functional groups. These functionalized N-acetylgalactosamine-analogs may be used in the preparation of targeted delivery of oligonucleotide-based therapeutics.Type: ApplicationFiled: April 25, 2024Publication date: August 29, 2024Inventors: Wing C. Poon, Xiaoyang Guan, David Yu, Ruiming Zou, Xiaojun Li, Michael Su, Gang Zhao, Gengyu Du, Yun-Chiao Yao, Aldrich N.K. Lau
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Publication number: 20240247023Abstract: Embodiments of the present application relate to functionalized N-acetylgalactosamine analogs, methods of making, and uses of the same. In particular, polyvalent N-acetylgalactosamine analogs may be prepared by utilizing a wide variety of linkers containing functional groups. These functionalized N-acetylgalactosamine analogs may be used in the preparation of targeted delivery of oligonucleotide-based therapeutics.Type: ApplicationFiled: November 27, 2023Publication date: July 25, 2024Inventors: Wing C. Poon, Gang Zhao, Gengyu Du, Yun-Chiao Yao, Ruiming Zou, Aldrich N.K. Lau, David Yu, Guijun Yu, Zhixia Li
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Patent number: 11581695Abstract: The disclosure provides a high-frequency-reproducibility laser frequency stabilization method and device based on multi-point acquisition of laser tube temperature. The laser frequency stabilization device includes: a frequency stabilization control circuit. The frequency stabilization control circuit includes a polarizing beam splitter, an optical power conversion circuit, an A/D conversion circuit, a temperature measuring circuit, a microprocessor, a D/A converter and a heating film driver. The polarizing beam splitter is disposed outside any one of laser transmitting holes. The optical power conversion circuit is disposed on reflection and refraction optical paths of the polarizing beam splitter. The optical power conversion circuit, the A/D conversion circuit, the microprocessor, the D/A converter, the heating film driver and a plurality of groups of heating films are sequentially in one-way connection.Type: GrantFiled: September 16, 2020Date of Patent: February 14, 2023Assignee: HARBIN INSTITUTE OF TECHNOLOGYInventors: Hongxing Yang, Yun Zou, Ziqi Yin, Jing Li, Pengcheng Hu, Jiubin Tan
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Patent number: 11075051Abstract: A radiation emission device is provided. The radiation emission device may include an anode, a first cathode, a heating device and an enclosure. The first cathode may include a first filament that emit an electron beam striking the anode to generate radioactive rays for imaging. The heating device may be located outside of the first cathode and be configured to warm up the anode. The enclosure may be configured to enclosure the first cathode and the anode.Type: GrantFiled: December 29, 2018Date of Patent: July 27, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yun Zou, Xi Zhang, Dun Li, Yanfeng Du, Haining Sun
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Publication number: 20210215650Abstract: The present invention relates to a method for analyzing a metalloprotein in a biological sample capable of continuously maintaining conditions of LC-ICPMS constant to measure a metalloprotein with high data reliability. The method for analyzing a metalloprotein which is a complex in a biological sample, the metalloprotein being a complex in which a biomolecule and a metal element bind to each other, includes: treating a biological sample which has been subjected to a pretreatment by liquid chromatography to separate the metalloprotein, and analyzing the separated metalloprotein by inductively coupled plasma mass spectrometry, wherein an ammonium acetate solution is used as a mobile phase.Type: ApplicationFiled: April 12, 2019Publication date: July 15, 2021Inventors: Satoshi YAMAKI, Yun ZOU
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Publication number: 20210203121Abstract: The disclosure provides a high-frequency-reproducibility laser frequency stabilization method and device based on multi-point acquisition of laser tube temperature. The laser frequency stabilization device includes: a frequency stabilization control circuit. The frequency stabilization control circuit includes a polarizing beam splitter, an optical power conversion circuit, an A/D conversion circuit, a temperature measuring circuit, a microprocessor, a D/A converter and a heating film driver. The polarizing beam splitter is disposed outside any one of laser transmitting holes. The optical power conversion circuit is disposed on reflection and refraction optical paths of the polarizing beam splitter. The optical power conversion circuit, the A/D conversion circuit, the microprocessor, the D/A converter, the heating film driver and a plurality of groups of heating films are sequentially in one-way connection.Type: ApplicationFiled: September 16, 2020Publication date: July 1, 2021Inventors: Hongxing YANG, Yun ZOU, Ziqi YIN, Jing LI, Pengcheng HU, Jiubin TAN
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Publication number: 20200355651Abstract: The present disclosure relates to a detection method for congeners of short-chain chlorinated paraffins as well as a device for realizing the detection method. The detection method includes the following steps: adding an internal standard substance to a test sample; subjecting the test sample to a separation process using a comprehensive two-dimensional gas chromatograph formed by connecting a non-polar or weak-polar column and a medium-polar column in series via a modulator; and detecting the sample by a mass analyzer employing a negative chemical ion source after the separation process. The method according to the present disclosure enables accurate qualitative analysis as well as accurate quantitative measurement for short-chain chlorinated paraffins. The detection is extremely accurate yet can be easily carried out with simple operations.Type: ApplicationFiled: April 17, 2020Publication date: November 12, 2020Applicant: Shimadzu CorporationInventors: Yun ZOU, Naoki HAMADA, Liang DONG
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Patent number: 10757796Abstract: A system and method for generating X-rays are disclosed. The method may include emitting an electron beam from a cathode to a focal track of a rotating target. The method may further include deflecting the electron beam onto a first region of the focal track at a first time, and deflecting the electron beam onto a second region of the focal track at a second time. The first region of the focal track may be separated from the second region of the focal track. The method may further include generating X-rays in response to the electron beam deflected onto the first region of the focal track or onto the second region of the focal track.Type: GrantFiled: October 21, 2019Date of Patent: August 25, 2020Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Xi Zhang, Patrick Kling, Yun Zou, Alexander Zamyatin
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Publication number: 20200053859Abstract: A system and method for generating X-rays are disclosed. The method may include emitting an electron beam from a cathode to a focal track of a rotating target. The method may further include deflecting the electron beam onto a first region of the focal track at a first time, and deflecting the electron beam onto a second region of the focal track at a second time. The first region of the focal track may be separated from the second region of the focal track. The method may further include generating X-rays in response to the electron beam deflected onto the first region of the focal track or onto the second region of the focal track.Type: ApplicationFiled: October 21, 2019Publication date: February 13, 2020Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Xi ZHANG, Patrick KLING, Yun ZOU, Alexander ZAMYATIN
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Patent number: 10455678Abstract: A system and method for generating X-rays are disclosed. The method may include emitting an electron beam from a cathode to a focal track of a rotating target. The method may further include deflecting the electron beam onto a first region of the focal track at a first time, and deflecting the electron beam onto a second region of the focal track at a second time. The first region of the focal track may be separated from the second region of the focal track. The method may further include generating X-rays in response to the electron beam deflected onto the first region of the focal track or onto the second region of the focal track.Type: GrantFiled: June 29, 2017Date of Patent: October 22, 2019Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Xi Zhang, Patrick Kling, Yun Zou, Alexander Zamyatin
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Publication number: 20190206653Abstract: A radiation emission device is provided. The radiation emission device may include an anode, a first cathode, a heating device and an enclosure. The first cathode may include a first filament that emit an electron beam striking the anode to generate radioactive rays for imaging. The heating device may be located outside of the first cathode and be configured to warm up the anode. The enclosure may be configured to enclosure the first cathode and the anode.Type: ApplicationFiled: December 29, 2018Publication date: July 4, 2019Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yun ZOU, Xi ZHANG, Dun LI, Yanfeng DU, Haining SUN
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Patent number: 10283034Abstract: The present disclosure provides a pixel structure including a plurality of pixel cells arranged into a plurality of rows. Each row includes a plurality of pixel-cell groups, each including a predetermined number of subpixels with different colors arranged along the row direction. The pixel-cell groups are arranged in a zigzag manner along a column direction. For any two neighboring rows, each subpixel in one row is divided into two secondary subpixels along the row direction, and each subpixel in the other row is divided into two secondary subpixels along the column direction. The colors of the subpixels in each pixel-cell group of the odd-numbered rows include a first color, a second color, and a third color, respectively along the row direction. The colors of the subpixels in each pixel-cell group of the even-numbered rows are the second color, the third color, and the first color, respectively along the row direction.Type: GrantFiled: January 8, 2018Date of Patent: May 7, 2019Assignee: Shanghai Tianma AM-OLED Co., Ltd.Inventors: Yun Zou, Yang Yang, Xiurui Hu
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Publication number: 20180343728Abstract: A system and method for generating X-rays are disclosed. The method may include emitting an electron beam from a cathode to a focal track of a rotating target. The method may further include deflecting the electron beam onto a first region of the focal track at a first time, and deflecting the electron beam onto a second region of the focal track at a second time. The first region of the focal track may be separated from the second region of the focal track. The method may further include generating X-rays in response to the electron beam deflected onto the first region of the focal track or onto the second region of the focal track.Type: ApplicationFiled: June 29, 2017Publication date: November 29, 2018Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Xi ZHANG, Patrick KLING, Yun ZOU, Alexander ZAMYATIN
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Patent number: 10136868Abstract: Some embodiments are associated with an X-ray source configured to generate X-rays directed toward an object, wherein the X-ray source is to: (i) generate a first energy X-ray pulse, (ii) switch to generate a second energy X-ray pulse, and (iii) switch back to generate another first energy X-ray pulse. A detector may be associated with multiple image pixels, and the detector includes, for each pixel: an X-ray sensitive element to receive X-rays; a first storage element and associated switch to capture information associated with the first energy X-ray pulses; and a second storage element and associated switch to capture information associated with the second energy X-ray pulse. A controller may synchronize the X-ray source and detector.Type: GrantFiled: September 3, 2015Date of Patent: November 27, 2018Assignee: General Electric CompanyInventors: Yun Zou, John Michael Sabol, Brian David Yanoff, Hao Lai, Biju Jacob, Katelyn Rose Nye, Feng Chen
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Publication number: 20180130396Abstract: The present disclosure provides a pixel structure including a plurality of pixel cells arranged into a plurality of rows. Each row includes a plurality of pixel-cell groups, each including a predetermined number of subpixels with different colors arranged along the row direction. The pixel-cell groups are arranged in a zigzag manner along a column direction. For any two neighboring rows, each subpixel in one row is divided into two secondary subpixels along the row direction, and each subpixel in the other row is divided into two secondary subpixels along the column direction. The colors of the subpixels in each pixel-cell group of the odd-numbered rows include a first color, a second color, and a third color, respectively along the row direction. The colors of the subpixels in each pixel-cell group of the even-numbered rows are the second color, the third color, and the first color, respectively along the row direction.Type: ApplicationFiled: January 8, 2018Publication date: May 10, 2018Inventors: Yun ZOU, Yang YANG, Xiurui HU