Abstract: The present invention relates to the field of pharmaceutical and chemical engineering, and specifically relates to a weakly acidic microenvironment-sensitive aptamer for tumors, a triptolide conjugate. The conjugate is formed by conjugation between the 14-position hydroxyl group of triptolide and the aptamer via an acetal ester linking bond, which is an acid-sensitive linking bond with a cleavage condition of (pH=3.5-6.5), which is much less pH-sensitive and is more likely to cleave under the tumor microenvironment. Based on the characteristics of the aptamer targeting the highly expressed proteins on the membrane surface of tumor cells, the conjugate delivered triptolide targeted to tumor cells and mediated endocytosis to reach the lysosome; based on the characteristics of the acidic environment of lysosomes, the acetal ester linking bond released intact triptolide in the lysosomal acidic environment, targeting and killing of tumor cells.

Abstract: A connector connected with a circuit board includes a housing and a main body. The housing has an insert hole and an accommodating portion. The main body is fixed in the accommodating portion and has a plurality of signal terminals and a plurality of pins arranged in the same direction. When a plug is plugged in the insert hole, a plugging direction of the plug is perpendicular to the circuit board.

Abstract: A connector and the housing thereof, which is equipped with at least one light emitting element having at least one lead, are disclosed. The connector includes at least one connecting base, at least one light emitting element, and a housing. The housing covers at least a portion of the connecting base and has a body and at least one fastening structure. The light emitting element is accommodated in the body, and the fastening structure is connected with the body and fastens the lead of the light emitting element so as to connect and fix the light emitting element with the body.

Abstract: A connector connected with a circuit board includes a housing and a main body. The housing has an insert hole and an accommodating portion. The main body is fixed in the accommodating portion and has a plurality of signal terminals and a plurality of pins arranged in the same direction. When a plug is plugged in the insert hole, a plugging direction of the plug is perpendicular to the circuit board.

Abstract: A connector electrically connected to a peripheral component interconnect express card includes a first body and a second body. The first body includes a plurality of connection holes provided to be correspondingly plugged by a plurality of plugs having electrical contacts. The second body is connected to the first body and volumetrically less than the first body. When the first and second bodies are connected, the connected first and second bodies has a top-view projecting profile corresponding to the shape of the peripheral component interconnect express card.

Abstract: A connector is provided. The connector includes a lighting element, a plurality of pins; and a housing covering the pins. The house includes at least one slot receiving the lighting element and having a plurality of engaging elements disposed on the slot and at least one stopper disposed at an open side of the slot.

Abstract: A connector and the housing thereof, which is equipped with at least one light emitting element having at least one lead, are disclosed. The connector includes at least one connecting base, at least one light emitting element, and a housing. The housing covers at least a portion of the connecting base and has a body and at least one fastening structure. The light emitting element is accommodated in the body, and the fastening structure is connected with the body and fastens the lead of the light emitting element so as to connect and fix the light emitting element with the body.

Abstract: A connector includes a circuit board and a housing. The housing has a body and a ground element, wherein the ground element is connected with the body and is disposed with respect to the circuit board. The ground element is in electrical contact with a ground end of the circuit board by clipping or hooking. The ground element and the body are integrally formed as a single piece, and the ground element is elastically deformable.