Patents by Inventor Yun-Bo Shi

Yun-Bo Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE AND TARGETING OF CD98 LIGHT-CHAIN PROTEINS IN THERAPIES FOR THYROID HORMONE DISORDERS
    Publication number: 20090081212
    Abstract: The invention is related to the normalization of thyroid hormone transport by modulation of 4F2hc, CD981c, and the 4F2hc-CD981c heterodimer. Approaches to identify compounds that modulate thyroid hormone disorders, methods of identifying agonists and antagonists that modulate thyroid hormone disorders, and methods of making pharmaceuticals that ameliorate a thyroid hormone disorder are described herein.
    Type: Application
    Filed: July 29, 2008
    Publication date: March 26, 2009
    Applicant: The Government of the U.S.A., as Represented by the Secretary, Department of health
    Inventors: Yun-Bo Shi, Peter M. Taylor, George J. Peter, James W.A. Ritchie
  • Tri-functional nanospheres
    Publication number: 20060263906
    Abstract: Trifunctional nanoparticles have excellent fluorescence, magnetism, and cell recognition, which can be easily manipulated, tracked, and conveniently used to capture target cells. The surface-immobilized molecules of the TFNs might be optionally changed on demand for the purposes of bioanalysis, biomedical imaging, diagnosis, and the combinatorial screening of drugs. The nanoparticle is formed from a mesoporous polymer; a magnetic material adhering to the mesoporous polymer; a fluorescent dye adhering to the mesoporous polymer; and a biomaterial coupled to the mesoporous polymer, where the mesoporous polymer has been treated with hydrazine, and the biomaterial has been treated with an oxidizing agent.
    Type: Application
    Filed: May 24, 2005
    Publication date: November 23, 2006
    Inventors: Dai-Wen Pang, Hai-Yan Xie, Guo-Ping Wang, Zhi-Ling Zhang, Er-Qun Song, Yun-Bo Shi
  • Use and targeting of CD98 light-chain proteins in therapies for thyroid hormone disorders
    Publication number: 20030171286
    Abstract: The invention is related to the normalization of thyroid hormone transport by modulation of 4F2hc, CD98lc, and the 4F2hc-CD98lc heterodimer. Approaches to identify compounds that modulate thyroid hormone disorders, methods of identifying agonists and antagonists that modulate thyroid hormone disorders, and methods of making pharmaceuticals that ameliorate a thyroid hormone disorder are described herein.
    Type: Application
    Filed: November 27, 2002
    Publication date: September 11, 2003
    Inventors: Yun-Bo Shi, Peter M. Taylor, George J. Peter, James W.A. Ritchie