Abstract: The present disclosure provides a nanoparticle, a preparation process thereof, a method for treating cancer, a method for enhancing effect of a liver cancer drug, a method for ameliorating tumor hypoxia, and a method for enhancing effect of a liver cancer vaccine by using the nanoparticle.

Abstract: The present disclosure provides a nanoparticle, a preparation process thereof, a method for treating cancer, a method for enhancing effect of a liver cancer drug, a method for ameliorating tumor hypoxia, and a method for enhancing effect of a liver cancer vaccine by using the nanoparticle.

Abstract: The present disclosure provides a nanoparticle, a preparation process thereof, a method for enhancing effect of a liver cancer drug, and a method for ameliorating tumor hypoxia by using the nanoparticle.

Abstract: The present disclosure provides a nanoparticle, a preparation process thereof, a method for enhancing effect of a liver cancer drug, and a method for ameliorating tumor hypoxia by using the nanoparticle.

Abstract: Provided is a method for treatment of liver cancer and inhibition of metastasis with CXCR4-targeted nanoparticle. A CXCR4 antagonist is used as a targeting molecule to modify a lipid carrier for the formation of nanoparticle carrying an anti-angiogenesis drug or an anti-angiogenic nucleotide. Such nanoparticle can enhance the accumulation and uptake of the drug and nucleotide in liver cancer cells as well as sensitize the liver cancer cells to treatment of said drug and nucleotide, providing a synergistic suppression of angiogenesis and tumor progression. Furthermore, the CXCR4-targeted nanoparticle can effectively inhibit metastasis of liver cancer. The pharmaceutical composition is an injectable composition; hence, is suitable for clinical application for the treatment of liver cancer.

Abstract: The present invention is related to a method for ameliorating liver fibrosis in a subject. The present invention utilizes copolymers of polyethylene glycol and poly (D, L-lactide-co-glycolide) to form nanoparticle composition containing tyrosine kinase inhibitor, such as Sorafenib. The use of nanoparticle composition is non-toxic and can increase the stability and decrease the release of drug in blood circulation. The pharmaceutical composition is in an injectable form. The nanoparticle composition containing tyrosine kinase inhibitor of the present invention can effectively ameliorate liver fibrosis including decreasing extracellular matrix accumulation, suppressing hepatic stellate cell activity, shrinking of abnormal blood vessel, and lowering microvascular density in fibrotic liver; hence is suitable for clinical application for the treatment of liver fibrosis.

Abstract: Various techniques are disclosed that allow phenotype-related data to be aggregated from any number of online sources. A statistical model may be generated using the aggregated data that, based on (epi)genome, microbiome, or other omics information regarding a subject, predicts the probability of the subject having the phenotype.

Abstract: Antigens and B-cell epitopes derived from dengue virus type 1 are provided. The antigens are specifically immunoreactive with sera from individuals infected with dengue virus type 1 but not reactive with sera from healthy individuals and individuals infected with dengue virus type 2. The antigens and epitopes are useful for development of diagnostic kits and reagents, and are useful tools as well in determining whether an individual is infected with dengue virus type 1, and for distinguishing infection from dengue virus type 2.

Abstract: A device for supporting two interfaces including a TV image card and a LCD panel image card is disclosed. The device can be inserted by the TV or the LCD panel image card according to the user's different needs. The device utilizes the built-in graphic capability of the North Bridge for supporting the TV or the LCD panel image output. By using the device of the invention, it is not necessary to design different motherboards for meeting clients' different demands. Furthermore, no image card is required according to the invention, and thus corresponding costs decrease.

Abstract: A portable computer capable of displaying a foreign image signal from an external image-signal generator is disclosed. The portable computer includes a computer host generating a local image signal in a first operation condition and suspending the local image signal in a second operation condition, a signal transferring device in communication with a signal output channel of the external image-signal generator for transferring the foreign image signal received from the image signal generator, and a display device electrically connected to the computer host and the signal transferring device for receiving and displaying the local image signal in the first operation condition, and receiving and displaying the foreign image signal in the second operation condition.

Abstract: A device for supporting two interfaces including a TV image card and a LCD panel image card is disclosed. The device can be inserted by the TV or the LCD panel image card according to the user's different needs. The device utilizes the built-in graphic capability of the North Bridge for supporting the TV or the LCD panel image output. By using the device of the invention, it is not necessary to design different motherboards for meeting clients' different demands. Furthermore, no image card is required according to the invention, and thus corresponding costs decrease.

Abstract: A built-up heat exchanger including a seat and a plurality of radiators superposed on a top of the seat is provided. The seat is made of a thermal conductive material in sheet form and has at least two notches formed on a top surface thereof. The a plurality of radiators are made of a thermal conductive material in sheet form and are punched to form a plurality of upward extended fins and at least two downward projected ridges corresponding to the at least two notches on the seat, such that any of the radiators may be superposed on the top surface of the seat with the at least two downward projected ridges fitly received in the at least two notches. Since the number of fins formed on each radiator and the number of radiators superposed on the seat may be freely decided depending on actual need, the built-up heat exchanger may be used in different applications.

Abstract: A method for producing a radiator mainly including the steps of forming a base, forming a radiator fin, forming a foundation plate, and assembling the radiator fin, the foundation plate and the base to form a radiator. The radiator produced in the above method has simple structure and reduced weight and can therefore be quickly assembled at lowered production cost.

Abstract: A method of producing a built-up heat exchanger including the steps of cutting a thermal conductive material to provide a seat in sheet form, forming at least two spaced notches on a top surface of the seat, cutting a thermal conductive material to provide radiators in sheet form, punching the radiators so that a plurality of upward extended fins and at least two downward projected and spaced ridges are formed, applying glue over bottom surfaces of the ridges of the radiators, and superposing the radiators on the top surface of the seat with the bottom-glued ridges fitted in the notches on the seat. The number of fins formed on each radiator and the number of radiators superposed on the seat may be decided depending on the actual need in different applications of the built-up heat exchanger.