Abstract: A data transmission method includes receiving, by a gateway of an integration platform as a service (iPaaS) system, a data transmission request transmitted by the iPaaS system, the iPaaS system being deployed on a first virtual private cloud (VPC) in a cloud network. The method further includes determining an address identifier of the service to be accessed by the iPaaS system, and a first transmission connection between the gateway and a data transmission circuitry associated with the service. The data transmission circuitry is connected to an Intranet, and the service is deployed in the Intranet or in a second VPC. The method further includes transmitting the data transmission request and the address identifier of the service from the gateway to the data transmission circuitry through the first transmission connection, where the data transmission circuitry transmits the data transmission request of the iPaaS system to the service.

Abstract: A data transmission method includes receiving, by a gateway of an integration platform as a service (iPaaS) system, a data transmission request transmitted by the iPaaS system, the iPaaS system being deployed on a first virtual private cloud (VPC) in a cloud network. The method further includes determining an address identifier of the service to be accessed by the iPaaS system, and a first transmission connection between the gateway and a data transmission circuitry associated with the service. The data transmission circuitry is connected to an Intranet, and the service is deployed in the Intranet or in a second VPC. The method further includes transmitting the data transmission request and the address identifier of the service from the gateway to the data transmission circuitry through the first transmission connection, where the data transmission circuitry transmits the data transmission request of the iPaaS system to the service.

Abstract: Systems and methods for estimating treatment effects in randomized controlled trials using covariate adjusted stratification and pseudovalue regression in accordance with embodiments of the invention are illustrated. One embodiment includes a method for estimating treatment effects in randomized controlled trials, where the method includes receiving external data of previous randomized clinical trials. The method further includes generating sets of one or more subject characteristics of a plurality of trial subjects, estimating binary outcomes of trial subjects using a stratification process, and estimating time-to-event (TTE) treatment effects of trial subjects using pseudovalue regression.