Patents by Inventor Yunfu Luo

Yunfu Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIMIDINE TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF
    Publication number: 20240409560
    Abstract: A pyrimidine tricyclic derivative and a pharmaceutical application thereof. Specifically disclosed are a compound as represented by formula (I), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 12, 2024
    Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yunfu LUO, Guoli ZHANG, Shaolong LI, Weizhi GE, Shuhui CHEN
  • 2,6-PIPERIDINEDIONE COMPOUND AND APPLICATION THEREOF
    Publication number: 20240400547
    Abstract: Provided are a 2,6-piperidinedione compound and an application thereof. Particularly provided are a compound represented by formula (II), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 21, 2022
    Publication date: December 5, 2024
    Inventors: Maoyi LEI, Yu XU, Shaohui WANG, Yunfu LUO, Shuhui CHEN
  • Heterocycloalkyl compounds as CCR2 / CCR5 antagonists
    Publication number: 20240360112
    Abstract: The invention relates to a series of compounds with heterocycloalkyl, or isomers or pharmaceutically acceptable salts thereof, and to a use thereof in manufacturing a medicine of treatment CCR2/CCR5 antagonist-related diseases, specifically to a compound of Formula ( ), or an isomer or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 3, 2024
    Publication date: October 31, 2024
    Inventors: Yunfu LUO, Yuyong BA, Yanhe CHEN, Shuhui CHEN
  • ALKYL CARBOXYLIC ACID COMPOUNDS AND APPLICATION THEREOF
    Publication number: 20240317696
    Abstract: A series of alkyl carboxylic acid compounds and an application thereof, and relates in particular to compounds represented by formula (II) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 10, 2022
    Publication date: September 26, 2024
    Inventors: Yunfu LUO, Weizhi GE, Shaolong LI, Guoli ZHANG, Shuhui CHEN
  • HETEROARYL-3-PIPERIDINEDIONE COMPOUND AND USE THEREOF
    Publication number: 20240317722
    Abstract: A heteroaryl-3-piperidinedione compound and the use thereof. Particularly disclosed are a compound represented by formula (II) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 12, 2022
    Publication date: September 26, 2024
    Applicant: Medshine Discovery Inc.
    Inventors: Maoyi Lei, Yu Xu, Yunfu Luo, Shuhui Chen
  • FUSED TRI-CYCLIC COMPOUND AS A PDE3/PDE4 DUAL INHIBITOR
    Publication number: 20240294526
    Abstract: Provided is a fused tri-cyclic compound as PDE3/PDE4 dual inhibitor, and a use thereof in the preparation of drugs for PDE3/PDE4 associated diseases, particularly in medicinal functions such as chronic obstructive pulmonary disease (COPD). Provided are specifically a compound of formula (I) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 22, 2024
    Publication date: September 5, 2024
    Inventors: Yunfu LUO, Jianfeng PAN, Guoli ZHANG, Sheng SU, Yong WANG, Shuhui CHEN
  • CRYSTAL FORM OF TRIAZOLOPYRIDINE-SUBSTITUTED INDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR
    Publication number: 20240246985
    Abstract: Provided are a crystal form of a triazolopyridine-substituted indazole compound and a preparation method therefor; and specifically disclosed are a crystal form of a compound as represented by formula (I) and a preparation method therefor.
    Type: Application
    Filed: June 23, 2022
    Publication date: July 25, 2024
    Inventors: Sheng SU, Yunfu LUO, Guoli ZHANG
  • Fused tri-cyclic compound as PDE3/PDE4 dual inhibitor
    Patent number: 11993596
    Abstract: Provided is a fused tri-cyclic compound as PDE3/PDE4 dual inhibitor, and a use thereof in the preparation of drugs for PDE3/PDE4 associated diseases, particularly in medicinal functions such as chronic obstructive pulmonary disease (COPD). Provided are specifically a compound of formula (I) and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: May 28, 2024
    Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yunfu Luo, Jianfeng Pan, Guoli Zhang, Sheng Su, Yong Wang, Shuhui Chen
  • Bicyclic compound that acts as CRBN protein regulator
    Patent number: 11905276
    Abstract: A compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and disclosed is an application thereof in the preparation of a medication for treating diseases related to a CRBN receptor.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: February 20, 2024
    Assignee: MEDSHINE DISCOVERY INC.
    Inventors: Yunfu Luo, Maoyi Lei, Yu Xu, Junmiao Li, Guoli Zhang, Jinghong Dong, Shuhui Chen
  • BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR
    Publication number: 20230348441
    Abstract: A compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and disclosed is an application thereof in the preparation of a medication for treating diseases related to a CRBN receptor.
    Type: Application
    Filed: September 14, 2020
    Publication date: November 2, 2023
    Inventors: Yunfu LUO, Maoyi LEI, Yu XU, Junmiao LI, Guoli ZHANG, Jinghong DONG, Shuhui CHEN
  • FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF
    Publication number: 20230322745
    Abstract: Disclosed are a fused tricyclic derivative and a pharmaceutical application thereof. Specifically disclosed are a compound represented by formula (III) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 28, 2021
    Publication date: October 12, 2023
    Inventors: Peng ZHANG, Yunfu LUO, Feng GAO, Shuhui CHEN
  • PYRIMIDINE-BASED TRICYCLIC COMPOUND AND USE THEREOF
    Publication number: 20230257398
    Abstract: The present invention relates to a pyrimidine-based tricyclic compound and a use thereof, and specifically, relates to a pyrimidine-based tricyclic compound and a use thereof in preparation of a drug for treating a related disease. Specifically, disclosed are a compound represented by formula (II), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 17, 2023
    Inventors: Yunfu LUO, Guoli ZHANG, Shaolong LI, Weizhi GE, Shuhui CHEN
  • PYRIDINE DERIVATIVE AND APPLICATION THEREOF
    Publication number: 20230183221
    Abstract: Disclosed are a series of compounds having pyridine structures or pharmaceutically acceptable salts thereof, and an application thereof in the preparation of drugs for the treatment of related diseases. Specifically, disclosed is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 15, 2023
    Inventors: Yunfu LUO, Yuyong BA, Shuhui CHEN
  • BENZOPYRAZOLE COMPOUND
    Publication number: 20230167068
    Abstract: Disclosed is a benzopyrazole compound. Specifically disclosed are a compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 30, 2020
    Publication date: June 1, 2023
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Sheng SU, Xiawei WEI, Yunfu LUO, Guoli ZHANG, Yong WANG, Shuhui CHEN
  • PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME
    Publication number: 20230158152
    Abstract: A proteolysis targeting chimera (PROTAC), and an application thereof in preparation of a drug for treating a related disease. Specifically disclosed are a compound as represented by formula (I) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 17, 2021
    Publication date: May 25, 2023
    Inventors: Maoyi LEI, Lei PENG, Yunfu LUO, Yu XU, Junmiao LI, Xinyuan DENG, Zisheng KANG, Weizhi GE, GuoIi ZHANG, Shuhui CHEN
  • CRYSTAL OF TRICYCLIC COMPOUND ACTING ON CRBN PROTEIN AND PREPARATION METHOD THEREFOR
    Publication number: 20230123104
    Abstract: Disclosed are a crystal of a tricyclic compound acting on CRBN protein and a preparation method therefor, specifically relating to a crystal of a compound of formula (I) and a preparation method therefor. An application of the crystal in the preparation of drugs for treating CRBN protein-related diseases is further comprised.
    Type: Application
    Filed: March 5, 2021
    Publication date: April 20, 2023
    Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Maoyi LEI, Yu XU, Yunfu LUO, Zhenliang SHAN
  • Medical application of pyrimidine sulfonamides derivatives
    Patent number: 11628168
    Abstract: The present disclosure provides application of a compound in conformity with a general formula I and an isomer or pharmaceutically acceptable salt thereof to preparation of a medicinal composition for treating or preventing a high altitude disease. The high altitude disease is selected from an acute high altitude disease and a chronic high altitude disease generated in a high altitude environment with an altitude of 2,000 m or above.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: April 18, 2023
    Assignees: CHINESE PLA GENERAL HOSPITAL, SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT COMPANY, LTD.
    Inventors: Kunlun He, Xiaojian Gao, Chunlei Liu, Zeyu Zhang, Xin Li, Chen Li, Yunfu Luo, Maoyi Lei, Junmiao Li, Yiwei Wang
  • CRYSTAL OF PDE3/PDE4 DUAL INHIBITOR AND USE THEREOF
    Publication number: 20230115817
    Abstract: Provided are a crystal of a tricyclic compound as shown in formula (I) or a pharmaceutically acceptable salt thereof and a preparation method therefor, and the use thereof in preparing a drug for treating PDE3- and/or PDE4-related diseases.
    Type: Application
    Filed: January 15, 2021
    Publication date: April 13, 2023
    Inventors: Wenjun YAO, Yunfu LUO, Peng ZHANG, Ting YAO
  • PHARMACEUTICAL COMPOSITION OF TRICYCLIC PDE3/PDE4 DUAL INHIBITOR COMPOUND
    Publication number: 20230060174
    Abstract: A pharmaceutical composition of a tricyclic PDE3/PDE4 dual inhibitor compound and a preparation method therefor, specifically relating to a pharmaceutical composition of a compound of formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, and use thereof
    Type: Application
    Filed: January 15, 2021
    Publication date: March 2, 2023
    Inventors: Miao YANG, Yuanyuan SUN, Wanjing LI, Zhong XU, Pengyue BAO, Jing GAO, Ping DONG, Hui HUI, Xiongfeng JI, Yunfu LUO
  • Heterocycloalkyl compounds as CCR2 / CCR5 antagonists
    Publication number: 20230002360
    Abstract: The invention relates to a series of compounds with heterocycloalkyl, or isomers or pharmaceutically acceptable salts thereof, and to a use thereof in manufacturing a medicine of treatment CCR2/CCR5 antagonist-related diseases, specifically to a compound of Formula (I), or an isomer or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 24, 2020
    Publication date: January 5, 2023
    Inventors: Yunfu LUO, Yuyong BA, Yanhe CHEN, Shuhui CHEN