Patents by Inventor Yung-hyo Koh

Yung-hyo Koh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N[S(4-aryl-triazol-3-yl)alpha-mercaptoacetyl]-p-amino benzoic acids as HIV reverse transcriptase inhibitors
    Publication number: 20060270725
    Abstract: A series of S-triazolyl ?-mercaptoacetanilides having N-(?-mercaptoacetyl) p amino benzoic acid derivatives. are provided, where Q is CO2H, or a salt or ester thereof, or a C(O)N-linked amino acid. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
    Type: Application
    Filed: November 30, 2005
    Publication date: November 30, 2006
    Inventors: Jean-Luc Girardet, Yung-hyo Koh, Martha de la Rosa, Zhi Hong, Stanley Lang
  • Non-nucleoside reverse transcriptase inhibitors
    Publication number: 20060135556
    Abstract: Various carbonyl amides are employed in vitro and in vivo as non-nucleoside inhibitors of a reverse transcriptase, and particularly of HIV reverse transcriptase. Therefore, contemplated compounds may be employed in the treatment of HIV infected patients. Further contemplated aspects include pharmaceutical compositions comprising therapeutically effective amounts of contemplated compounds.
    Type: Application
    Filed: August 22, 2003
    Publication date: June 22, 2006
    Inventors: Jean-Luc Girardet, Zhijun Zhang, Robert Hamatake, Martha de la Rosa, Esmir Gunic, Zhi Hong, Hong Kim, Yung-Hyo Koh, Shahul Nilar, Stephanie Shaw, Nanhua Yao
  • Antiviral phosphonate compounds and methods therefor
    Publication number: 20040023921
    Abstract: Pharmaceutical compositions comprise a nucleotide analog with a phosphonate group at a concentration effective to act as a substrate and/or inhibitor of a viral polymerase, and especially of the HCV RNA dependent RNA polymerase.
    Type: Application
    Filed: April 29, 2003
    Publication date: February 5, 2004
    Inventors: Zhi Hong, Yung-hyo Koh, Jae Hoon Shim, Jean-Luc Girardet