Abstract: The present disclosure discloses a thin film transistor (TFT)-based bootstrap structure amplifier, and a chip. The amplifier includes an input circuit, an output buffer, and several bootstrap structure units. The bootstrap structure units include a TFT and a capacitor. The drain and the gate of the TFT are both connected to the same voltage node. The source of the TFT is connected to one end of the capacitor. The other end of the capacitor is connected to an output signal node. The output buffer is formed by connecting the sources and drains of several TFTs in series. Two ends of the output buffer are respectively connected to an input voltage node and an output signal node. The source of the TFT in each bootstrap structure unit is connected to the gates of the TFTs in one output buffer. The input circuit includes an input signal node, the output signal node, and a grounding node. The present disclosure can increase circuit gain and have a simple structure and low fabrication cost.