Patents by Inventor Yunliang LI

Yunliang LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240263250
    Abstract: An insertion and deletion (InDel) molecular marker of a hisD gene of ultrasonically-mutagenized Salmonella typhimurium (S. typhimurium) and use thereof are provided. Through ultrasonic mutagenesis to S. typhimurium and sequencing, it is found that all InDel mutations occur in a core mutation region of the hisD gene. Therefore, the core mutation region is used as the InDel molecular marker to determine an insertion or a deletion of a gene reverse mutation, and the InDel molecular marker can also be used to analyze a relationship between a sequence of the hisD gene and a function of a protein encoded thereby.
    Type: Application
    Filed: December 20, 2021
    Publication date: August 8, 2024
    Applicant: JIANGSU UNIVERSITY
    Inventors: Haile MA, Siyu RUAN, Yunliang LI, Yaoyong JI, Anqi ZHOU, Pengfei XIE, Bobo ZHAO, Xiaoshuang LIU, Yaxuan XU, Yanling WU
  • Publication number: 20240218316
    Abstract: A Bacillus velezensis (B. velezensis) strain bred through ultrasound-assisted adaptive evolution and use thereof are provided. In the present disclosure, a B. velezensis strain (B. velezensis CICC 23571) is used as a starting strain, and an ultrasound-assisted adaptive evolution process is performed, where a proportion of organic nitrogen in a medium is continuously reduced and proportions of inorganic nitrogen and a sugar source are increased to obtain a B. velezensis mutant strain with a high polypeptide yield. Different metabolic pathways in the mutant strain are enhanced, such that the mutant strain can efficiently convert inorganic nitrogen into organic nitrogen or reduce the deaminization of organic nitrogen, and finally a yield of polypeptides is greatly increased.
    Type: Application
    Filed: December 16, 2021
    Publication date: July 4, 2024
    Applicant: JIANGSU UNIVERSITY
    Inventors: Siyu RUAN, Haile MA, Yunliang LI, Yaoyong JI, Xiaojing WANG, Anqi ZHOU, Pengfei XIE, Xiaoshuang LIU