Patents by Inventor Yunlong Lu
Yunlong Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12295939Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: August 3, 2023Date of Patent: May 13, 2025Assignee: The Board of Trustees of the University of IllinoisInventors: Gregory R Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yangfeng Li
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Publication number: 20230381137Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: ApplicationFiled: August 3, 2023Publication date: November 30, 2023Inventors: Gregory R THATCHER, Rui XIONG, Jiong ZHAO, Yunlong LU, Lauren GUTGESELL, Carlo Ivan ROSALES, Yangfeng LI
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Patent number: 11759450Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: February 6, 2019Date of Patent: September 19, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yangfeng Li
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Patent number: 11600930Abstract: A broadband panel array antenna includes a polarization layer, a radiating layer and a feed layer which are sequentially stacked from top to bottom. The feed layer is used for converting a single path of TE10 mode signals into a plurality of paths of same-power in-phase TE10 mode signals and transmitting the plurality of paths of TE10 mode signals to the radiating layer. The radiating layer is used for radiating the plurality of paths of TE10 mode signals from the feed layer to a free space. The polarization layer is used for rotating the polarization direction of an electric field generated by the radiating layer to reduce the side lobe in an E-plane direction diagram and an H-plane direction diagram. The broadband panel array antenna has the advantages of being low in side lobe, high in gain and efficiency, and low in machining cost.Type: GrantFiled: May 17, 2021Date of Patent: March 7, 2023Assignee: Ningbo UniversityInventors: Yang You, Jifu Huang, Ling Zhang, Qingchun You, Yunlong Lu
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Patent number: 11381000Abstract: A low-sidelobe plate array antenna includes a radiation layer and a feed layer. The radiation layer is superimposed on the feed layer and includes a first plate and a radiation array disposed on the first plate. The radiation array is formed by n2 radiation units which are distributed in 2(k-1) rows and 2(k-1) columns. Each radiation unit in the radiation layer is constituted by two first radiation assemblies and two second radiation assemblies. Each first radiation assembly comprises a first rectangular bar, a first rectangular cavity, a second rectangular cavity and a third rectangular cavity. The first rectangular cavity, the second rectangular cavity and the third rectangular cavity in the first radiation assembly are stacked in presence of an azimuth deviation to form a three-layer coupled structure, and the first rectangular bar located in the first rectangular cavity can better restrain cross polarization and reduce the sidelobe.Type: GrantFiled: December 7, 2020Date of Patent: July 5, 2022Assignee: Ningbo UniversityInventors: Yang You, Jifu Huang, Ling Zhang, Qingchun You, Yunlong Lu
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Publication number: 20220062230Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: ApplicationFiled: February 6, 2019Publication date: March 3, 2022Inventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yanfeng Li
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Publication number: 20210359422Abstract: A broadband panel array antenna includes a polarization layer, a radiating layer and a feed layer which are sequentially stacked from top to bottom. The feed layer is used for converting a single path of TE10 mode signals into a plurality of paths of same-power in-phase TE10 mode signals and transmitting the plurality of paths of TE10 mode signals to the radiating layer. The radiating layer is used for radiating the plurality of paths of TE10 mode signals from the feed layer to a free space. The polarization layer is used for rotating the polarization direction of an electric field generated by the radiating layer to reduce the side lobe in an E-plane direction diagram and an H-plane direction diagram. The broadband panel array antenna has the advantages of being low in side lobe, high in gain and efficiency, and low in machining cost.Type: ApplicationFiled: May 17, 2021Publication date: November 18, 2021Applicant: Ningbo UniversityInventors: Yang YOU, Jifu HUANG, Ling Zhang, Qingchun YOU, Yunlong Lu
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Publication number: 20210359420Abstract: A low-sidelobe plate array antenna includes a radiation layer and a feed layer. The radiation layer is superimposed on the feed layer and includes a first plate and a radiation array disposed on the first plate. The radiation array is formed by n2 radiation units which are distributed in 2(k-1) rows and 2(k-1) columns. Each radiation unit in the radiation layer is constituted by two first radiation assemblies and two second radiation assemblies. Each first radiation assembly comprises a first rectangular bar, a first rectangular cavity, a second rectangular cavity and a third rectangular cavity. The first rectangular cavity, the second rectangular cavity and the third rectangular cavity in the first radiation assembly are stacked in presence of an azimuth deviation to form a three-layer coupled structure, and the first rectangular bar located in the first rectangular cavity can better restrain cross polarization and reduce the sidelobe.Type: ApplicationFiled: December 7, 2020Publication date: November 18, 2021Applicant: Ningbo UniversityInventors: Yang YOU, Jifu HUANG, Ling Zhang, Qingchun YOU, Yunlong Lu
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Patent number: 10703747Abstract: This invention is benzothiophene-based selective mixed estrogen receptor downregulators and their compositions and uses to treat estrogen-related disorders.Type: GrantFiled: April 24, 2019Date of Patent: July 7, 2020Assignee: The Board of Directors of the University of IllinoisInventors: Gregory R. Thatcher, Rui Xiong, Yunlong Lu, Jiong Zhao, Debra A. Tonetti
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Publication number: 20190248780Abstract: This invention is benzothiophene-based selective mixed estrogen receptor downregulators and their compositions and uses to treat estrogen-related disorders.Type: ApplicationFiled: April 24, 2019Publication date: August 15, 2019Applicant: The Board of Trustees of the University of IllnoisInventors: Gregory R. Thatcher, Rui Xiong, Yunlong Lu, Jiong Zhao, Debra A. Tonetti