Patents by Inventor Yunping Dai

Yunping Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Afucosylated monoclonal antibody
    Patent number: 11168143
    Abstract: Provided is an afucosylated monoclonal antibody. The monoclonal antibody is a human IgG antibody and has an afucosylated sugar chain structure at a heavy-chain sugar chain binding site. Also provided are application of the monoclonal antibody in the preparation of antineoplastic drugs, and a composition containing the monoclonal antibody. Compared with a fucosylated monoclonal antibody, the provided afucosylated monoclonal antibody has higher biological activity in vitro and in vivo and can be used for developing more effective therapeutic monoclonal antibody drugs.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: November 9, 2021
    Inventors: Bo Tang, Ran Zhang, Jianmin Zhao, Jianwu Wang, Yunping Dai
  • AFUCOSYLATED MONOCLONAL ANTIBODY
    Publication number: 20200270358
    Abstract: Provided is an afucosylated monoclonal antibody. The monoclonal antibody is a human IgG antibody and has an afucosylated sugar chain structure at a heavy-chain sugar chain binding site. Also provided are application of the monoclonal antibody in the preparation of antineoplastic drugs, and a composition containing the monoclonal antibody. Compared with a fucosylated monoclonal antibody, the provided afucosylated monoclonal antibody has higher biological activity in vitro and in vivo and can be used for developing more effective therapeutic monoclonal antibody drugs.
    Type: Application
    Filed: July 24, 2017
    Publication date: August 27, 2020
    Applicants: BEIJING GEFUCURE BIOTECHNOLOGY LIMITED COMPANY, Wuxi Kingenew Biotechnology Limited Company
    Inventors: Bo Tang, Ran Zhang, Jianmin Zhao, Jianwu Wang, Yunping Dai