Patents by Inventor Yunshan Wu

Yunshan Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240163684
    Abstract: The disclosure discloses a method and system for constructing and analyzing a knowledge graph of a wireless communication network protocol, and a device and a medium. The method for constructing and analyzing the knowledge graph of the wireless communication network protocol includes: defining entities and a relation between the entities according to endogenous factors of a wireless communication network protocol, defining a triplet based on the defined entities and the defined relation between the entities, and constructing a knowledge graph of the endogenous factors of the wireless communication network protocol based on the defined triplet; and performing association analysis between any nodes in the knowledge graph to acquire an association relation hidden between the endogenous factors of the wireless communication network protocol.
    Type: Application
    Filed: October 15, 2021
    Publication date: May 16, 2024
    Inventors: Shiwen HE, Liangpeng WANG, Xiangwu ZHANG, Zhijie WU, Yiting YANG, Sui ZOU, Yongming HUANG, Yunshan YI, Xiaohu YOU
  • Patent number: 11660285
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 30, 2023
    Assignees: Guangdong Provincial Hospital of TCM, The Second Affiliated Hospital Of Guangzhou University of Chinese Medicine, The Second Clinical College Of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy Of Chinese Medical Sciences
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng
  • Publication number: 20230064939
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Application
    Filed: December 30, 2019
    Publication date: March 2, 2023
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng
  • Patent number: 10925913
    Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: February 23, 2021
    Assignees: THE SECOND AFFILIATED HOSPITAL OF GUANGZHOU UNIVERSITY OF CHINESE MEDICINE, GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
    Inventors: Bo Liu, Wei Mao, Xusheng Liu, Peng Xu, Xiaodong Han, Wen Zhou, Fangfang Xu, Yuanchao Li, Yiqi Yang, Jinbao Deng, Lilan Wu, Yunshan Wu, Weiying Chen, Ruimin Tian, Jinjian Lu, Yuqin Zhang
  • Publication number: 20200069757
    Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 5, 2020
    Inventors: Bo LIU, Wei MAO, Xusheng LIU, Peng XU, Xiaodong HAN, Wen ZHOU, Fangfang XU, Yuanchao LI, Yiqi YANG, Jinbao DENG, Lilan WU, Yunshan WU, Weiying CHEN, Ruimin TIAN, Jinjian LU, Yuqin ZHANG
  • Patent number: 9506096
    Abstract: The present invention relates to the field of biology, in particular to a sugar preparation method by using biomass sweet potato dregs for microbial fermentation as a sugar source. The liquid sugar product prepared with the method of the present invention essentially comprises the ingredient of glucose. The method of the present invention is of simple process, high specificity, good product quality and high yield, and solves the serious environmental pollution problem of the sweet potato dregs, thus having a good industrial application prospect.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: November 29, 2016
    Assignee: SHANDONG HONGHE SUNKEEN BIOTECHNOLOGY CO. LTD.
    Inventors: Yunshan Wu, Gonghong Yan, Yong Yi, Zheng'en Kou, Zhen Wu
  • Publication number: 20150044730
    Abstract: The present invention relates to the field of biology, in particular to a sugar preparation method by using biomass sweet potato dregs for microbial fermentation as a sugar source. The liquid sugar product prepared with the method of the present invention essentially comprises the ingredient of glucose. The method of the present invention is of simple process, high specificity, good product quality and high yield, and solves the serious environmental pollution problem of the sweet potato dregs, thus having a good industrial application prospect.
    Type: Application
    Filed: April 1, 2013
    Publication date: February 12, 2015
    Applicant: SHANDONG HONGHE SUNKEEN BIOTECHNOLOGY CO. LTD.
    Inventors: Yunshan Wu, Gonghong Yan, Yong Yi, Zheng'en Kou, Zhen Wu