Patents by Inventor Yunxiao Li
Yunxiao Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240377115Abstract: A compressor assembly includes a first compressor, a second compressor, a first oil separator, a second oil separator, a storage container, a gas-liquid separator, a liquid balance pipe, and a gas balance pipe. The first compressor has a first air return port, and the second compressor has a second air return port. The first oil separator has a first oil outlet, the second oil separator has a second oil outlet, and the storage container has a refrigerant inlet, the first oil outlet and the second oil outlet both being in communication with the refrigerant inlet. The gas-liquid separator has a first gas separation outlet, a second gas separation outlet, a first oil return hole and a second oil return hole, the first gas separation outlet and the first oil return hole both being in communication with the first gas return port.Type: ApplicationFiled: June 2, 2022Publication date: November 14, 2024Inventors: Hongwei LI, Mingren WANG, Yunxiao DING, Zhijun TAN, Kongxiang WU, Yunpeng JIANG, Yusheng ZHANG, Huayong LI, Jianhong LU
-
Publication number: 20240298643Abstract: Provided are a benzimidazole compound as represented by formula (I) or a salt thereof, a preparation method therefor, and the use thereof. The benzimidazole compound or the salt thereof has excellent insecticidal and acaricidal effects, and can display acaricidal effects especially when same is used at a low concentration.Type: ApplicationFiled: February 22, 2022Publication date: September 12, 2024Inventors: Laijun ZHANG, Yu LIU, Ranjin LIU, Yingrui CUI, Yuqi WANG, Shiling WANG, Ruijie FENG, Zhanru ZHAO, Xinhao WEI, Yahui LI, Yaoyao DU, Chen GONG, Yunxiao SUN, Shien FAN, Qiangqiang GUO, Wei GUO, Jie GAO, Yingshuai LIU, Ning LI
-
Publication number: 20240294551Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S, G13D, Q61H, Q61L or G12C. The compounds have a general Formula I?: wherein the variables of Formula I? are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.Type: ApplicationFiled: March 25, 2024Publication date: September 5, 2024Applicant: AMGEN INC.Inventors: Ryan Paul Wurz, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Xiaofen LI, John STELLWAGEN, Kexue LI, Brian Alan LANMAN, Michael M. YAMANO, Wei ZHAO, Benjamin WIGMAN, Fabien EMMETIERE, Albert K. AMEGADZIE, Christopher P. MOHR, Aaron C. SIEGMUND, Rene RAHIMOFF, Zhichen WU, Adriano BAUER, Andrew SMALIGO, Quentin Tercenio, Qingyian Liu, Shon K. Booker
-
POSITION DETERMINATION METHOD AND APPARATUS, AND AIR CONDITIONING SYSTEM AND READABLE STORAGE MEDIUM
Publication number: 20240240823Abstract: The present disclosure provides a method and device for position determination, an air conditioning system, and a readable storage medium. The method for position determination includes: acquiring return air temperature information of each indoor unit; determining a first correlation coefficient between every two indoor units based on the return air temperature information; classifying indoor units based on the first correlation coefficient to obtain a number of classified groups; and generating relative position information in each classified group based on the first correlation coefficient by taking any one of the indoor units as a locating point. Maintenance personnel are not required to manually maintain a relative position relation of indoor units. Therefore, the maintenance difficulty of the relative position relation of indoor units is reduced, and a time cost and a labor cost required for maintenance are reduced accordingly.Type: ApplicationFiled: November 5, 2021Publication date: July 18, 2024Inventors: Bin LI, Ruixian YANG, Chunyuan ZHENG, Yunxiao DING, Xiaoqiang ZHAI -
Patent number: 11993183Abstract: A seat slide device includes a pair of sliders each including a fixed rail, a movable rail slidably guided by the fixed rail, a bracket on the movable rail configured so that front and rear sides swing opposite to each other in a vertical direction with a longitudinal-intermediate part as a fulcrum, a support bracket supported on the bracket via a hinge and configured to rotate in only one direction from a predetermined orientation about an lateral-direction axis relative to the bracket, a movement-restricting portion configured to restrict sliding of the movable rail while a rear part of the bracket is raised and to release the restriction while the rear part of the bracket is lowered; and a towel bar connecting each support bracket. The hinge part prohibits a rotation of the support bracket while the towel bar is lifted and permits the rotation while the towel bar is lowered.Type: GrantFiled: December 30, 2021Date of Patent: May 28, 2024Assignee: Adient US LLCInventors: Motohiko Ozawa, Naoto Komiya, Atsunori Matsui, Yunxiao Li, Laxmikant Indi, Frederick L. Wilkinson, Sean M. Osinski, Valentin Muresan, Wenting Zhang
-
Publication number: 20230211708Abstract: A seat slide device includes a pair of sliders each including a fixed rail, a movable rail slidably guided by the fixed rail, a bracket on the movable rail configured so that front and rear sides swing opposite to each other in a vertical direction with a longitudinal-intermediate part as a fulcrum, a support bracket supported on the bracket via a hinge and configured to rotate in only one direction from a predetermined orientation about an lateral-direction axis relative to the bracket, a movement-restricting portion configured to restrict sliding of the movable rail while a rear part of the bracket is raised and to release the restriction while the rear part of the bracket is lowered; and a towel bar connecting each support bracket. The hinge part prohibits a rotation of the support bracket while the towel bar is lifted and permits the rotation while the towel bar is lowered.Type: ApplicationFiled: December 30, 2021Publication date: July 6, 2023Inventors: Motohiko Ozawa, Naoto Komiya, Atsunori Matsui, Yunxiao Li, Laxmikant Indi, Frederick L. Wilkinson, Sean M. Osinski, Valentin Muresan, Wenting Zhang
-
Publication number: 20230052348Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: October 14, 2021Publication date: February 16, 2023Applicant: AMGEN INC.Inventors: Sean P BROWN, David Karl BEDKE, Michael R. DEGRAFFENREID, Jiasheng FU, Zhinghong LI, Felix GONZALEZ LOPEZ DE TURISO, Ana GONZALEZ BUENROSTRO, Michael W. GRIBBLE JR., Michael G. JOHNSON, Todd J. KOHN, Kexue LI, Yunxiao LI, Mike Elias LIZARZABURU, Yosup REW, Joshua TAYGERLY, Yingcai WANG, Xuelei YAN, Ming YU, Jiang ZHU, Manuel ZANCANELLA, Xian Yun JIAO, Liusheng ZHU, Xianghong WANG, Julio C. MEDINA, Jason A. DUQUETTE, Jonathan B. HOUZE, Marc VIMOLRATANA, Mario G. CARDOZO, Alan C. CHENG
-
Patent number: 11364248Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: August 17, 2018Date of Patent: June 21, 2022Assignee: AMGEN INC.Inventors: Sean P. Brown, Kexue Li, Yunxiao Li, Anthony B. Reed, Brian Alan Lanman
-
Patent number: 11306107Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: February 24, 2017Date of Patent: April 19, 2022Assignee: AMGEN INC.Inventors: Sean P. Brown, David Karl Bedke, Michael R. Degraffenreid, Jiasheng Fu, Zhihong Li, Felix Gonzalez Lopez De Turiso, Ana Gonzalez Buenrostro, Michael W. Gribble, Jr., Michael G. Johnson, Todd J. Kohn, Kexue Li, Yunxiao Li, Mike Elias Lizarzaburu, Yosup Rew, Joshua Taygerly, Yingcai Wang, Xuelei Yan, Ming Yu, Jiang Zhu, Manuel Zancanella, Xian Yun Jiao, Liusheng Zhu, Xianghong Wang, Julio C. Medina, Jason A. Duquette, Jonathan B. Houze, Marc Vimolratana, Mario G. Cardozo, Alan C. Cheng
-
Patent number: 11279712Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stenoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: August 27, 2018Date of Patent: March 22, 2022Assignee: AMGEN INC.Inventors: Sean P. Brown, Yunxiao Li, Paul E. Harrington, Brian Alan Lanman, Jonathan D. Low, Ana Elena Minatti, Vu Van Ma, Kexue Li
-
Patent number: 11273743Abstract: A mat mounting structure for mounting a mat on a seat back frame in a seat back may have a guide wire attachable to the mat configured to receive a force from a back of an occupant on the seat back. The guide wire may have a straight part extending linearly in a longitudinal direction of the seat back frame on a head side or a root side of the seat back frame. A bushing including a penetration hole in which the straight part is insertable in the longitudinal direction may be included in the structure. An attachment hole part in the seat back frame may also be part of the structure. The bushing may be detachably engageable with and attachable to the attachment hole part.Type: GrantFiled: December 22, 2020Date of Patent: March 15, 2022Assignees: Adient Engineering and IP GmbH, Honda Motor Co., Ltd.Inventors: Frederick L. Wilkinson, Sean M. Osinski, Yunxiao Li, Wenting Zhang, Naoto Komiya, Laxmikant Indi, Toshimitsu Mizukoshi, Taiji Misono, Hiroki Ikeda, Hiromitsu Nagatomo, Yuki Fukuda, Souhei Noguchi
-
Patent number: 11224601Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: September 23, 2020Date of Patent: January 18, 2022Assignee: AMGEN INC.Inventors: Paul E. Harrington, Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan Lanman, Kexue Li, Yunxiao Li, Jonathan D. Low, Ana Elena Minatti, Alexander J. Pickrell, Markian M. Stec, Joshua Taygerly
-
Publication number: 20210230189Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: February 24, 2017Publication date: July 29, 2021Applicant: AMGEN INC.Inventors: Sean P. BROWN, David Karl BEDKE, Micheal R. DEGRAFFENREID, Jiasheng FU, Zhihong LI, Felix GONZALEZ LOPEZ TURISO, Ana GONZALEZ BUENROSTRO, Micheal W. GRIBBLE, JR., Micheal G. JOHNSON, Todd J. KOHN, Kexue LI, Yunxiao LI, Mike Elias LIZARZABURU, Yosup REW, Joshua TAYGERLY, Yingcal WANG, Xuelei YAN, Ming YU, Jiang ZHU, Manuel ZANCANELLA, Xian Yun JIAO, Liusheng ZHU, Xianghong WANG, Julio C. MEDINA, Jason A. DUQUETTE, Jonathan B. HOUZE, Marc VIMOLRATANA, Marlo G. CARDOZO, Alan C. CHENG
-
Publication number: 20200360399Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: August 17, 2018Publication date: November 19, 2020Applicant: AMGEN INC.Inventors: Sean P. BROWN, Kexue LI, Yunxiao LI, Anthony B. REED, Brian Alan LANMAN
-
Patent number: 10836779Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: September 5, 2018Date of Patent: November 17, 2020Assignee: AMGEN INC.Inventors: Sean P. Brown, Yunxiao Li, Mike Elias Lizarzaburu, Brian S. Lucas, Nick A. Paras, Joshua Taygerly, Marc Vimolratana, Xianghong Wang, Ming Yu, Manuel Zancanella, Liusheng Zhu, Ana Gonzalez Buenrostro, Zhihong Li
-
Patent number: 10821115Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: February 6, 2020Date of Patent: November 3, 2020Assignee: AMGEN INC.Inventors: Paul E. Harrington, Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan Lanman, Kexue Li, Yunxiao Li, Jonathan D. Low, Ana Elena Minatti, Alexander J. Pickrell, Markian M. Stec, Joshua Taygerly
-
Publication number: 20200247821Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stenoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: August 27, 2018Publication date: August 6, 2020Applicant: AMGEN INC.Inventors: Sean P. BROWN, Yunxiao LI, Paul E. HARRINGTON, Brian Alan LANMAN, Jonathan D. LOW, Ana Elena MINATTI, Vu Van MA, Kexue LI
-
Publication number: 20200171043Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: February 6, 2020Publication date: June 4, 2020Applicant: AMGEN INC.Inventors: Paul E. HARRINGTON, Kate ASHTON, Sean P. BROWN, Matthew R. KALLER, Todd J. KOHN, Brian Alan LANMAN, Kexue LI, Yunxiao LI, Jonathan D. LOW, Ana Elena MINATTI, Alexander J. PICKRELL, Markian M. STEC, Joshua TAYGERLY
-
Patent number: 10632128Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: GrantFiled: August 22, 2019Date of Patent: April 28, 2020Assignee: AMGEN INC.Inventors: Paul E. Harrington, Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan Lanman, Kexue Li, Yunxiao Li, Jonathan D. Low, Ana Elena Minatti, Alexander J. Pickrell, Markian M. Stec, Joshua Taygerly
-
Publication number: 20200062780Abstract: Provided herein are compounds that are useful intermediates that may used to synthesize myeloid cell leukemia 1 protein (Mcl-1) inhibitors. Also provided are Mcl-1 inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: September 13, 2019Publication date: February 27, 2020Applicant: Amgen Inc.Inventors: Sean P. BROWN, Yunxiao LI, Mike Elias LIZARZABURU, Brian S. LUCAS, Nick A. PARAS, Joshua TAYGERLY, Marc VIMOLRATANA, Xianghong WANG, Ming YU, Manuel ZANCANELLA, Liusheng ZHU, Ana GONZALEZ BUENROSTRO, Zhihong LI