Patents by Inventor Yunyi Wei

Yunyi Wei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying potential agonists or antagonists using the three-dimensional structure of caspase-7
    Publication number: 20080187980
    Abstract: The present invention relates to a data storage medium encoded with the structural coordinates of crystallized molecules and molecular complexes which comprise the active site binding pockets of caspase-7. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also related to methods of using the structure coordinates to solve the structure of similar or homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to caspase-7 or homologues thereof. This invention also relates to molecules or molecular complexes which comprise the active site binding pockets of caspase-7 or close structural homologues of the active site binding pockets.
    Type: Application
    Filed: March 6, 2008
    Publication date: August 7, 2008
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventor: Yunyi Wei
  • Crystallizable compositions comprising a caspase-7
    Publication number: 20030224368
    Abstract: The present invention relates to a data storage medium encoded with the structural coordinates of crystallized molecules and molecular complexes which comprise the active site binding pockets of caspase-7. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also related to methods of using the structure coordinates to solve the structure of similar or homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to caspase-7 or homologues thereof. This invention also relates to molecules or molecular complexes which comprise the active site binding pockets of caspase-7 or close structural homologues of the active site binding pockets.
    Type: Application
    Filed: May 16, 2002
    Publication date: December 4, 2003
    Inventor: Yunyi Wei