Patents by Inventor Yunzhe Zhang

Yunzhe Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof
    Patent number: 11040952
    Abstract: Provided are a phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and a use thereof; the structure of said phthalazinone compound is as represented by formula I; the compound of said formula I is targeted to a viral nucleocapsid; it can inhibit the replication of a virus by means of interference of the viral nucleocapsid, has a potent activity for inhibiting HBV DNA replication and a good liver targeting, can stably exist and enrich in the liver, and is a new and effective anti-HBV inhibitor.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: June 22, 2021
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Youhong Hu, Jianping Zuo, Dong Lu, Li Yang, Limin Zeng, Feifei Liu, Yunzhe Zhang, Wuhong Chen, Xiankun Tong
  • PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF
    Publication number: 20200181109
    Abstract: Provided are a phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and a use thereof; the structure of said phthalazinone compound is as represented by formula I; the compound of said formula I is targeted to a viral nucleocapsid; it can inhibit the replication of a virus by means of interference of the viral nucleocapsid, has a potent activity for inhibiting HBV DNA replication and a good liver targeting, can stably exist and enrich in the liver, and is a new and effective anti-HBV inhibitor.
    Type: Application
    Filed: February 10, 2020
    Publication date: June 11, 2020
    Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Youhong Hu, Jianping Zuo, Dong Lu, Li Yang, Limin Zeng, Feifei Liu, Yunzhe Zhang, Wuhong Chen, Xiankun Tong