Patents by Inventor Yuping Li

Yuping Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11958838
    Abstract: Crystalline forms of compound 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2-dimethylbenzofuran-3-carboxamide, pharmaceutical compositions and the methods of preparation and the use thereof.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: April 16, 2024
    Assignee: Hutchmed Limited
    Inventors: Zhenping Wu, Wenji Li, Yuping Chu
  • Publication number: 20240099451
    Abstract: An aspect of the disclosure is related to a cleaning composition and a device to apply a cleaning composition. The device may include a container containing a cleaning composition to clean a surface of a dental appliance in an oral cavity, an applicator portion to apply the cleaning composition to the surface of the dental appliance in the oral cavity and a gap between the dental appliance and the oral cavity, the applicator having a portion to be deformed based on the gap width of the gap to be inserted into the gap to apply the cleaning composition in the gap, and an extruder to extrude the cleaning composition in the container through an outlet to the applicator portion and the portion, wherein the cleaning composition is essentially free of a dental abrasive agent, wherein the dental abrasive agent is a solid particle having a hardness harder than the hardness of the surface of the dental appliance.
    Type: Application
    Filed: June 29, 2023
    Publication date: March 28, 2024
    Inventors: Zachary Burkett, Yuping Li, Nicholas Aralis
  • Publication number: 20240067869
    Abstract: The present disclosure relates to a fracturing propping agent and a preparation method thereof. The fracturing propping agent comprises the following raw materials: dry sludge, quartz sand, coal ash, bauxite and clay.
    Type: Application
    Filed: November 11, 2022
    Publication date: February 29, 2024
    Inventors: Changming Su, Zhanqing Qu, Xinwu Zhu, Zuochen Li, Yuping Fan, Wei Liu, Wen Su, Kai Weng
  • Publication number: 20240041719
    Abstract: Dental whitening compositions, kits and systems exhibiting stability in viscosity and hydrogen peroxide concentration for an extended shelf life without refrigeration or other special storage conditions are provided herein. The composition may be in gel form and comprise a hydrogen peroxide or a hydrogen peroxide precursor, and a thickening agent comprising a vinylpyrrolidone polymer or copolymer. In some aspects, a kit may be provided comprising a two-part dental whitening system, wherein one part comprises a whitening agent, and a separate part comprises a strong base.
    Type: Application
    Filed: October 11, 2023
    Publication date: February 8, 2024
    Inventors: Yuping LI, Nicholas ARALIS, Wen GU
  • Publication number: 20230329977
    Abstract: Dental remineralization compositions and methods are provided herein. In an aspect of the disclosure, a remineralization composition comprises a remineralizing agent and a polyanion serving as a multi-point anchor to localize the remineralizing agent on tooth surfaces. The remineralization composition can comprise a non-ionic surfactant that promotes formation of complexes between the remineralizing agent and the polyanion. In some aspects, the polyanion comprises poly(acrylic acid) sodium salt. In some aspects, the remineralizing agent comprises at least one of bioactive calcium containing compounds, bioactive calcium containing complexes, and free calcium ions formed once the bioactive calcium containing compounds contacts or mixes with water. In some aspects, the remineralization composition is free of phosphates and/or phosphate salts.
    Type: Application
    Filed: April 13, 2023
    Publication date: October 19, 2023
    Inventors: Yuyan JIAO, Wen GU, Yuping LI, Nicholas ARALIS
  • Publication number: 20230293500
    Abstract: An AK3287 formulation, and a preparation method therefor and an application thereof. In mass fraction, the formulation comprises: 0.05-20% of AK3287; 0-30% of an absorption enhancer; 5-99.95% of an oil-phase substance; 0-25% of an emulsifier; 0-5% of a preservative; and 0-70% of water, wherein the structure of AK3287 is shown in the drawing. AK3287 molecules in the formulation have high exposure in the skin, and the formulation can reduce the thickness of the skin at a scar and the ratio of the maximum thickness of the skin at the scar to the thickness of the normal skin; moreover, the relative density of TGF-? and type I collagen in the skin is reduced.
    Type: Application
    Filed: September 2, 2021
    Publication date: September 21, 2023
    Inventors: Cheng PENG, Yuping LI, Chunyan ZHOU, Gang ZOU, Haiqing YUAN, Jim Zhen WU
  • Publication number: 20230129930
    Abstract: Dental whitening compositions, kits and systems exhibiting stability in viscosity and hydrogen peroxide concentration for an extended shelf life without refrigeration or other special storage conditions are provided herein. The composition may be in gel form and comprise a hydrogen peroxide or a hydrogen peroxide precursor, and a thickening agent comprising a vinylpyrrolidone polymer or copolymer. In some aspects, a kit may be provided comprising a two-part dental whitening system, wherein one part comprises a whitening agent, and a separate part comprises a strong base.
    Type: Application
    Filed: January 18, 2022
    Publication date: April 27, 2023
    Inventors: Yuping LI, Nicholas ARALIS, Wen GU
  • Publication number: 20220387443
    Abstract: Disclosed is a pharmaceutical unit dosage composition including a plurality of enteric coated micro pellets. Each enteric coated micro pellet includes a core bead, an optional first sealing layer, an API layer including a Compound (I) having the following structure or a pharmaceutically acceptable salt thereof, an optional second sealing layer, and an enteric coating layer. Also disclosed is a method for the treatment and prophylaxis of RSV diseases including providing a Compound (I) and administering to a patient in need thereof a therapeutically effective amount of the Compound (I) so that t½ of the Compound (I) is about 6 to 13 hours.
    Type: Application
    Filed: October 29, 2020
    Publication date: December 8, 2022
    Inventors: Cheng PENG, Zhen Jim WU, Yuping LI, Chunyan ZHOU, Yuanyuan LI, Stephen TOOVEY, Haiqing YUAN
  • Publication number: 20220324726
    Abstract: The disclosure provides a repairing material for emergency treatment of a black and odorous surface water environment and its preparation method, belonging to the fields of environmental science and engineering technology. The preparation method of the disclosure specifically includes the following steps: (1) uniformly stirring activated carbon, calcium chloride, ammonia water solution, polyethylene glycol and water in a stirrer, then dropwise adding hydrogen peroxide, and after the completion of the dropwise adding, obtaining a calcium peroxide repairing material solution; (2) adding a sodium hydroxide solution to the calcium peroxide repairing material solution obtained in step (1) until a pH reaches 11.5, thereby obtaining a suspension; (3) centrifuging the suspension in step (2) to obtain a solid; and (4) washing the solid in step (3) with distilled water until a final pH of residual water reaches 8.4, and then drying the obtained precipitate to obtain the repairing material.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 13, 2022
    Inventors: Hengfeng Miao, Ziwen Chen, Yingying Jiang, Yuping Li, Wenquan Ruan
  • Patent number: 10969984
    Abstract: A network device may store domain name system (DNS) information in a DNS file in a first DNS store of a first control plane component included in the network device, the DNS information being associated with a plurality of DNS entries stored in a first DNS memory of the first control plane component; may transfer, based on storing the DNS information in the DNS file in the first DNS store, a copy of the DNS file from the first DNS store to a second DNS store of a second control plane component included in the network device, the copy of the DNS file including the DNS information associated with the plurality of DNS entries; and may transfer, based on detecting an event associated with the first control plane component, the DNS information from the copy of the DNS file to a second DNS memory of the second control plane component.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: April 6, 2021
    Assignee: Juniper Networks, Inc.
    Inventors: Zhijun Bao, Yuping Li, Yuan Tao
  • Publication number: 20200310670
    Abstract: A network device may store domain name system (DNS) information in a DNS file in a first DNS store of a first control plane component included in the network device, the DNS information being associated with a plurality of DNS entries stored in a first DNS memory of the first control plane component; may transfer, based on storing the DNS information in the DNS file in the first DNS store, a copy of the DNS file from the first DNS store to a second DNS store of a second control plane component included in the network device, the copy of the DNS file including the DNS information associated with the plurality of DNS entries; and may transfer, based on detecting an event associated with the first control plane component, the DNS information from the copy of the DNS file to a second DNS memory of the second control plane component.
    Type: Application
    Filed: March 27, 2019
    Publication date: October 1, 2020
    Inventors: Zhijun BAO, Yuping LI, Yuan TAO
  • Patent number: 10709733
    Abstract: In some examples, the disclosure relates to a method including applying biomimetic mineralization process to an enamel defect of a tooth, wherein the applied biomimetic mineralization process remineralizes the tooth in the enamel defect. For example, applying a biomimetic mineralization process may include applying a polymer stabilized biomimetic mineralization composition in the area of the enamel defect and matrices, wherein the biomimetic mineralization composition infiltrates into a porosity of the enamel defect and crystalizes to remineralize the enamel defect. An example polymer stabilized biomimetic mineralization composition includes calcium, phosphate, and a polyanionic additive.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 14, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Yuping Li, Alex Fok, Conrado Aparicio
  • Patent number: 10662095
    Abstract: An ozone-photocatalysis reactor, comprising: a shell layer (1); activated carbon layers (2) arranged in the shell layer (1); and at least one photoxidation unit arranged in the shell layer (1) and above the activated carbon layers (2). The photoxidation unit comprises a honeycomb activated carbon layer I (3), a light source layer and a honeycomb activated carbon bed layer II (4) sequentially from bottom to top. A gas inlet (7) and a water inlet (6) are formed in the shell layer below the activated carbon layers (2); a water outlet (9) and a gas outlet (10) are formed in the shell layer (1) above the photoxidation unit; and the activated carbon layers (2), at least one honeycomb activated carbon bed layer I (3) and at least one honeycomb activated carbon bed layer II (4) are loaded with a solid catalyst. The reactor uses ozone oxidation and ozone-photocatalysis sufficiently for sewage treatment, the treatment time is short, and the treatment efficiency is high.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: May 26, 2020
    Assignee: INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Yongbing Xie, Hongbin Cao, Yuxing Sheng, Yuping Li
  • Publication number: 20190112211
    Abstract: The present disclosure relates to a method for photocatalytic ozonation reaction, in which the silicon carbide material is used. By using the silicon carbide material for photocatalytic ozonation reaction, the present disclosure overcomes the problem of low photocatalytic efficiency of silicon carbide, utilizes photogenerated electrons therefrom with strong reducibility to reduce ozone molecules to efficiently produce hydroxyl radicals, so as to improve the oxidation capacity in the process. Whether visible light or ultraviolet light is coupled with ozone, the group has strong catalytic activity, moreover, the silicon carbide has low cost and good stability, which prolongs the life of catalyst for photocatalytic ozonation or device.
    Type: Application
    Filed: October 15, 2018
    Publication date: April 18, 2019
    Inventors: Hongbin CAO, Yongbing XIE, Yuping LI, Yuxing SHENG
  • Publication number: 20180078577
    Abstract: In some examples, the disclosure relates to a method including applying biomimetic mineralization process to an enamel defect of a tooth, wherein the applied biomimetic mineralization process remineralizes the tooth in the enamel defect. For example, applying a biomimetic mineralization process may include applying a polymer stabilized biomimetic mineralization composition in the area of the enamel defect and matrices, wherein the biomimetic mineralization composition infiltrates into a porosity of the enamel defect and crystalizes to remineralize the enamel defect. An example polymer stabilized biomimetic mineralization composition includes calcium, phosphate, and a polyanionic additive.
    Type: Application
    Filed: August 11, 2017
    Publication date: March 22, 2018
    Inventors: Yuping Li, Alex Fok, Conrado Aparicio
  • Publication number: 20170369346
    Abstract: An ozone-photocatalysis reactor, comprising: a shell layer (1); activated carbon layers (2) arranged in the shell layer (1); and at least one photoxidation unit arranged in the shell layer (1) and above the activated carbon layers (2). The photoxidation unit comprises a honeycomb activated carbon layer I (3), a light source layer and a honeycomb activated carbon bed layer II (4) sequentially from bottom to top. A gas inlet (7) and a water inlet (6) are formed in the shell layer below the activated carbon layers (2); a water outlet (9) and a gas outlet (10) are formed in the shell layer (1) above the photoxidation unit; and the activated carbon layers (2), at least one honeycomb activated carbon bed layer I (3) and at least one honeycomb activated carbon bed layer II (4) are loaded with a solid catalyst. The reactor uses ozone oxidation and ozone-photocatalysis sufficiently for sewage treatment, the treatment time is short, and the treatment efficiency is high.
    Type: Application
    Filed: May 12, 2015
    Publication date: December 28, 2017
    Inventors: Yongbing XIE, Hongbin CAO, Yuxing SHENG, Yuping LI
  • Patent number: 9708203
    Abstract: The present invention provides a method and a reactor for removing organic matters by immobilized-enzymatic electrode coupled electro-coagulation. In the method, in a single electrochemical system, an enzyme-modified electrode is combined with electro-coagulation to synergistically remove organic matters from water. Certain electrochemical parameters are controlled such that a polymerization reaction is performed between hydrogen peroxide generated by a cathode reaction and organic matters catalyzed by the immobilized-enzymatic electrode. After the polymerization reaction, the organic product enters an anode chamber through a pump. The organic product is precipitated and removed by performing a reaction between the organic product and different hydrolysis products from the electro-coagulation through a coagulating/flocculating effect of compression of a double electric layer, adsorption and electric neutralization as well as precipitation capture.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: July 18, 2017
    Assignee: Institute of Process Engineering, Chinese Academy
    Inventors: Hongbin Cao, He Zhao, Yuping Li, Haitao Li, Yi Zhang
  • Patent number: 9667672
    Abstract: A method, client, server and system for multi-person audio-video interaction are disclosed in the present invention, which belong to the field of internet terminal. The method includes: obtaining channel configuration information corresponding to current channel from a server; loading a scene module corresponding to the current channel according to the obtained channel configuration information and pre-stored configuration information; obtaining and displaying pictures or videos corresponding to the current channel from the server; displaying the text information by a simulation object corresponding to the client in a user interaction region of the scene module; and sending the text information to the server, when the text information that triggered by the user in the user interaction region of the scene module is received.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: May 30, 2017
    Assignee: GUANG-ZHOU HUADUO NETWORK TECHNOLOGY CO., LTD.
    Inventors: Zhou Chen, Yang Zhou, Yuping Li, Bowen Li, Yanmei Wang, Jie Chen
  • Publication number: 20170057821
    Abstract: The present invention relates to a synthetic method of graphitic carbon nitride material. The method involves a homogenous mixing of carbon nitride precursor and ammonium salt, and calcining the mixture to obtain a porous graphitic carbon nitride material. Wherein, the ammonium salt is any one or a combination of at least two which could release gaseous NH3 during thermolysis. The present invention uses thermolabile ammonium salt as a pore former; the thermolysis of ammonium salt could release soft gas bubbles during the calcination; the later burst of bubbles leads to the formation of nanoporous structure. The proposed method is template-free and environmentally-friendly, and the resultant material exhibits high photocatalytic activity in the field of gas and water decontamination.
    Type: Application
    Filed: August 30, 2016
    Publication date: March 2, 2017
    Inventors: Hongbin CAO, Yongbing XIE, Jiadong XIAO, Yuping LI, Yuxing SHENG
  • Publication number: 20160057175
    Abstract: A method, client, server and system for multi-person audio-video interaction are disclosed in the present invention, which belong to the field of internet terminal. The method includes: obtaining channel configuration information corresponding to current channel from a server; loading a scene module corresponding to the current channel according to the obtained channel configuration information and pre-stored configuration information; obtaining and displaying pictures or videos corresponding to the current channel from the server; displaying the text information by a simulation object corresponding to the client in a user interaction region of the scene module; and sending the text information to the server, when the text information that triggered by the user in the user interaction region of the scene module is received.
    Type: Application
    Filed: April 9, 2014
    Publication date: February 25, 2016
    Inventors: Zhou CHEN, Yang ZHOU, Yuping LI, Bowen LI, Yanmei WANG, Jie CHEN