Abstract: The present application pertains to antibodies or antigen-binding fragments that specifically bind to Klebsiella pneumoniae (K. pneumoniae) O2 antigen, antibodies or antigen-binding fragments that specifically bind to K. pneumoniae O1 antigen, and bispecific antibodies that specifically bind to K. pneumoniae O2 antigen and K. pneumoniae O1 antigen, and pharmaceutical compositions comprising the antibodies or antigen-binding fragments and/or bispecific antibodies, as well as methods of manufacture and uses thereof.

Abstract: The present invention is a system and method for generating predictions for various parameters in a reservoir. The invention includes receiving input data characterizing the reservoir and determining transient areas. The transient areas are determined by receiving data from the reservoir, transforming the data using discrete wavelet transformation to produce transformed data, removing outliers from the transformed data, identifying and reducing noise from in the transformed data and then detecting transient areas in the transformed data. A computer model is produced in response to the transient data and predictions for parameters in the reservoir are determined. These predictions are verified by comparing predictive values with a reservoir model and then the predictions for the various parameters can be used.

Abstract: The present invention is a method and apparatus for determining oil based mud contamination of a hydrocarbon fluid obtained from a wellbore during a formation testing. The invention includes receiving a model for simulating the contamination and receiving an empirical equation for computing the contamination. At a given pumping time, a simulated contamination is generated based on the model and an empirically computed contamination is generated based on the first empirical equation. The simulated contamination and empirically computed contamination are compared and a determination as to which is more reliable is made. Revision of the first model or first empirical equation based is then performed.

Abstract: The present invention is a method and apparatus for determining oil based mud contamination of a hydrocarbon fluid obtained from a wellbore during a formation testing. The invention includes receiving a model for simulating the contamination and receiving an empirical equation for computing the contamination. At a given pumping time, a simulated contamination is generated based on the model and an empirically computed contamination is generated based on the first empirical equation. The simulated contamination and empirically computed contamination are compared and a determination as to which is more reliable is made. Revision of the first model or first empirical equation based is then performed.

Abstract: The present invention is a system and method for generating predictions for various parameters in a reservoir. The invention includes receiving input data characterizing the reservoir and determining transient areas. The transient areas are determined by receiving data from the reservoir, transforming the data using discrete wavelet transformation to produce transformed data, removing outliers from the transformed data, identifying and reducing noise from in the transformed data and then detecting transient areas in the transformed data. A computer model is produced in response to the transient data and predictions for parameters in the reservoir are determined. These predictions are verified by comparing predictive values with a reservoir model and then the predictions for the various parameters can be used.

Abstract: A method, system and computer program product for simulating a fluid flow in a reservoir are disclosed. According to an embodiment, the current invention includes a method for simulating a fluid flow in a reservoir, the method comprising: providing an initial grid including multiple grid cells, each grid cell including a cell property; adjusting the initial grid to generated a modified grid in the case that a pressure equivalent radius under the initial grid is smaller than a well bore radius of the reservoir; and simulating the fluid flow in the reservoir based on the modified grid.

Abstract: A method, system and computer program product for simulating a fluid flow in a reservoir are disclosed. According to an embodiment, the current invention includes a method for simulating a fluid flow in a reservoir, the method comprising: providing an initial grid including multiple grid cells, each grid cell including a cell property; adjusting the initial grid to generated a modified grid in the case that a pressure equivalent radius under the initial grid is smaller than a well bore radius of the reservoir; and simulating the fluid flow in the reservoir based on the modified grid.