Patents by Inventor Yuqiao Fan

Yuqiao Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method of 4D chitosan-based thermosensitive hydrogel
    Patent number: 12252595
    Abstract: Medical material production and preparation, and a preparation method of a 4D chitosan-based thermosensitive hydrogel. First, chitosan is dissolved in acetic acid solution; a chitosan-based thermosensitive hydrogel is printed by a 4D bioprinter and lyophilized after solvent extraction, to obtain lyophilized chitosan; subsequently, aqueous ?-sodium glycerophosphate solution is prepared with ultrapure water and ?-sodium glycerophosphate, and then aqueous carboxymethyl chitosan solution is prepared with ultrapure water and aqueous ?-sodium glycerophosphate solution are charged into and mixed well with aqueous carboxymethyl chitosan solution to prepare a mixture; finally, the lyophilized chitosan is crosslinked with the mixture to obtain the 4D chitosan-based thermosensitive hydrogel. With scientific and reliable principles thereof, the present invention solves a problem that conventional thermosensitive hydrogels have uneven pore sizes, and improves the entrapment efficiency and ability of limbal stem cells.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: March 18, 2025
    Assignee: QINGDAO UNIVERSITY
    Inventors: Wenhua Xu, Yanhan Dong, Lixia Zhang, Yuqiao Fan
  • PREPARATION METHOD OF 4D CHITOSAN-BASED THERMOSENSITIVE HYDROGEL
    Publication number: 20210079170
    Abstract: Medical material production and preparation, and a preparation method of a 4D chitosan-based thermosensitive hydrogel. First, chitosan is dissolved in acetic acid solution; a chitosan-based thermosensitive hydrogel is printed by a 4D bioprinter and lyophilized after solvent extraction, to obtain lyophilized chitosan; subsequently, aqueous ?-sodium glycerophosphate solution is prepared with ultrapure water and ?-sodium glycerophosphate, and then aqueous carboxymethyl chitosan solution is prepared with ultrapure water and aqueous ?-sodium glycerophosphate solution are charged into and mixed well with aqueous carboxymethyl chitosan solution to prepare a mixture; finally, the lyophilized chitosan is crosslinked with the mixture to obtain the 4D chitosan-based thermosensitive hydrogel. With scientific and reliable principles thereof, the present invention solves a problem that conventional thermosensitive hydrogels have uneven pore sizes, and improves the entrapment efficiency and ability of limbal stem cells.
    Type: Application
    Filed: August 4, 2020
    Publication date: March 18, 2021
    Inventors: Wenhua Xu, Yanhan Dong, Lixia Zhang, Yuqiao Fan