Patents by Inventor Yuqing E. Chen

Yuqing E. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ELECTROPHILIC COMPOUNDS AND ELECTROPHILIC PRODRUGS FOR TREATING ANEURYSM
    Publication number: 20230241019
    Abstract: A method comprising administering to a subject having an aneurysm, suspected of having an aneurysm, or at risk of developing an aneurysm, a therapeutically effective amount of a compound selected from (i) a nitroalkene fatty acid, (ii) an unsaturated fatty acid having an electron withdrawing group, a leaving group, and a carbon-carbon double bond disposed between the electron withdrawing group and the leaving group, (iii) a thiolated nitro fatty acid, (iv) a dicarboxylic acid compound containing an electron withdrawing group, or a mixture of at least two of (i)-(iv).
    Type: Application
    Filed: April 20, 2021
    Publication date: August 3, 2023
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, The Regents of the University of Michigan
    Inventors: Francisco J. Schopfer, Bruce A. Freeman, Yang Zhao, Yuqing E. Chen, Jifeng Zhang
  • HISTONE-ACETYLATION-MODULATING AGENTS FOR THE TREATMENT AND PREVENTION OF ORGAN INJURY
    Publication number: 20230241076
    Abstract: Provided herein are agents that modulate histone acetylation and pathways downstream thereof, and methods for the treatment and prevention of organ injury therewith. In particular, provided herein are combinations of histone deacetylase (HDAC) inhibitors, bromodomain and extraterminal-containing protein family (BET) inhibitors, promoters of histone acetyl transferase (HAT) activity, mineralocorticoid receptor (MR) antagonists, nuclear factor erythroid 2-related factor 2 (NRF2) activators, and/or aldehyde dehydrogenase (ALDH) agonists, and methods of use thereof for the treatment and prevention of heart injury.
    Type: Application
    Filed: June 29, 2021
    Publication date: August 3, 2023
    Inventors: Yuqing E. Chen, Bertram Pitt, Ienglam Lei, Shuo Tian, Francis Pagani, Paul C. Tang, Zhong Wang
  • Nitrated lipids and methods of making and using thereof
    Patent number: 9867795
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: January 16, 2018
    Assignees: The UAB Research Foundation, The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20170119717
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: November 21, 2016
    Publication date: May 4, 2017
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Nitrated lipids and methods of making and using thereof
    Patent number: 9522156
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: December 20, 2016
    Assignees: The UAB Research Foundation, The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20160151391
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: February 10, 2016
    Publication date: June 2, 2016
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Nitrated lipids and methods of making and using thereof
    Patent number: 9295678
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: March 29, 2016
    Assignees: The UAB Research Foundation, The State of Oregon Acting By And Through The State Board Of Higher Education On Behalf of The University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20150246059
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: March 4, 2015
    Publication date: September 3, 2015
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Peptide compositions and methods for treating patients
    Patent number: 9062093
    Abstract: The present invention is directed to peptide compositions and methods of using the peptide compositions to treat prediabetes, diabetes, obesity, high blood pressure and metabolic syndrome.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: June 23, 2015
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Yuqing E. Chen, Changyong Xue, Jifeng Zhang
  • Nitrated lipids and methods of making and using thereof
    Patent number: 9006473
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: April 14, 2015
    Assignees: The UAB Research Foundation, The State of Oregon Acting By and Through the State Board of Higher Education on Behalf of The University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • PEPTIDE COMPOSITIONS AND METHODS FOR TREATING PATIENTS
    Publication number: 20140148382
    Abstract: The present invention is directed to peptide compositions and methods of using the peptide compositions to treat prediabetes, diabetes, obesity, high blood pressure and metabolic syndrome.
    Type: Application
    Filed: November 22, 2013
    Publication date: May 29, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Yuqing E. Chen, Changyong Xue, Jifeng Zhang
  • Peptide compositions and methods for treating patients
    Patent number: 8664177
    Abstract: The present invention is directed to peptide compositions and methods of using the peptide compositions to treat prediabetes, diabetes, obesity, high blood pressure and metabolic syndrome.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: March 4, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: Yuqing E. Chen, Changyong Xue, Jifeng Zhang
  • Nitrated Lipids and Methods of Making and Using Thereof
    Publication number: 20130210917
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: October 8, 2012
    Publication date: August 15, 2013
    Applicants: THE UAB RESEARCH FOUNDATION, Morehouse School of Medicine, Inc., University College Cardiff Consultants Limited, State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Nitrated lipids and methods of making and using thereof
    Patent number: 8309526
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: November 13, 2012
    Assignees: The UAB Research Foundation, University College Cardiff Consultants Ltd, Morehouse School of Medicine, University of Oregon
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • PEPTIDE COMPOSITIONS AND METHODS FOR TREATING PATIENTS
    Publication number: 20120208748
    Abstract: The present invention is directed to peptide compositions and methods of using the peptide compositions to treat prediabetes, diabetes, obesity, high blood pressure and metabolic syndrome.
    Type: Application
    Filed: February 10, 2012
    Publication date: August 16, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Yuqing E. Chen, Changyong Xue, Jifeng Zhang
  • Nitrated Lipids and Methods of Making and Using Thereof
    Publication number: 20100331268
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: June 9, 2010
    Publication date: December 30, 2010
    Applicants: THE UAB RESEARCH FOUNDATION, State of Oregon Acting By and Through the Board of Education on behalf of the University of Oregon
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Nitrated lipids and methods of making and using thereof
    Patent number: 7776916
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: August 17, 2010
    Assignees: The UAB Research Foundation, University of Oregon
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud