Patents by Inventor Yuquan Zou

Yuquan Zou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10886549
    Abstract: Simplified methods are disclosed for preparing a catalyst coated membrane that is reinforced with a porous polymer sheet (e.g. an expanded polymer sheet) for use in solid polymer electrolyte fuel cells. The methods involve forming a solid polymer electrolyte membrane by coating membrane ionomer solution onto a first catalyst layer and then applying the porous polymer sheet to the membrane ionomer solution coating, while it is still wet, such that the membrane ionomer solution only partially fills the pores of the porous polymer sheet. A second catalyst ink is then applied which fills the remaining pores of the porous polymer sheet. Not only are such methods simpler than many conventional methods, but surprisingly this can result in a marked improvement in fuel cell performance characteristics.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: January 5, 2021
    Assignees: Daimler AG, Ford Motor Company
    Inventors: Yuquan Zou, Scott McDermid, Massimiliano Cimenti, Shun-wen Amy Yang, Liviu Catoiu
  • Publication number: 20200369628
    Abstract: The present invention provides a crystal form of urate transporter 1 inhibitor and a preparation method and use thereof. The crystal form is characterized by a stable state of appearance and a capability of further improving the purity and storage stability of the compound, etc., and suitable as a pharmaceutical raw material.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 26, 2020
    Applicant: Tianjin Institute of Pharmaceutical Research Co., Ltd.
    Inventors: Guilong Zhao, Changying Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Xuyuan Liu, Yuqiang Liu, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Lida Tang, Meixiang Zou
  • Publication number: 20200361952
    Abstract: The present invention provides a compound having a structure of formula (I), a preparation method and use thereof, and a pharmaceutical composition containing the compound, wherein R is methyl, ethyl, propyl, vinyl or propenyl. The present invention also provides a crystalline form of the compound, a preparation method and use of the crystalline form, and a pharmaceutical composition comprising the crystalline form. The compounds having the structure of formula (I) of the present invention are present in a solid form, which not only can solve the problem of clopidogrel resistance, but also can solve the problem of severe hemorrhagic side effect and poor safety of some drugs, as well as the problem of poor stability of existing compounds. It can be developed into an ADP receptor antagonist antiplatelet agent with clear therapeutic effect, no resistance and better stability.
    Type: Application
    Filed: August 22, 2018
    Publication date: November 19, 2020
    Applicant: Tianjin Institute of Pharmaceutical Research Co., Ltd.
    Inventors: Changjiang Huang, Shijun Zhang, Lingjun Li, Lei Liu, Yuquan Li, Jing Yuan, Hui Yan, Songhui Wang, Xuemin Zheng, Qunchao Wei, Xuyuan Liu, Wei Wei, Weiren Xu, Lida Tang, Meixiang Zou
  • Patent number: 10566640
    Abstract: Improved additives can be used to prepare polymer electrolyte for membrane electrode assemblies in polymer electrolyte fuel cells. Use of these improved additives can not only improve durability and performance, but can also provide a marked performance improvement during initial conditioning of the fuel cells. The additives are chemical complexes comprising certain metal and organic ligand components.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: February 18, 2020
    Assignees: Daimler AG, Ford Motor Company
    Inventors: Keping Wang, Yunsong Yang, Carmen Chuy, Jing Li, Owen Thomas, Yuquan Zou
  • Patent number: 10403905
    Abstract: Simplified methods for preparing a catalyst coated membrane (CCM) for solid polymer electrolyte fuel cells. The CCM has two reinforcing, expanded polymer sheets and the methods involve forming the electrolyte membrane from ionomer solution during assembly of the CCM. Thus, the conventional requirement to obtain, handle, and decal transfer solid polymer sheets in CCM preparation can be omitted. Further, CCM structures with improved mechanical strength can be prepared by orienting the expanded polymer sheets such that the stronger tensile strength direction of one is orthogonal to the other. Such improved CCM structures can be fabricated using the simplified methods.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: September 3, 2019
    Assignees: Daimler AG, Ford Motor Company
    Inventors: Yuquan Zou, Owen Thomas, Scott McDermid, Yunsong Yang, Jing Li, Carmen Chuy
  • Publication number: 20190233381
    Abstract: Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.
    Type: Application
    Filed: June 26, 2017
    Publication date: August 1, 2019
    Inventors: Guilong Zhao, Changying Liu, Yuqiang Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Meixiang Zou, Lida Tang
  • Publication number: 20180323459
    Abstract: Simplified methods are disclosed for preparing a catalyst coated membrane that is reinforced with a porous polymer sheet (e.g. an expanded polymer sheet) for use in solid polymer electrolyte fuel cells. The methods involve forming a solid polymer electrolyte membrane by coating membrane ionomer solution onto a first catalyst layer and then applying the porous polymer sheet to the membrane ionomer solution coating, while it is still wet, such that the membrane ionomer solution only partially fills the pores of the porous polymer sheet. A second catalyst ink is then applied which fills the remaining pores of the porous polymer sheet. Not only are such methods simpler than many conventional methods, but surprisingly this can result in a marked improvement in fuel cell performance characteristics.
    Type: Application
    Filed: April 25, 2018
    Publication date: November 8, 2018
    Inventors: Yuquan Zou, Scott McDermid, Massimiliano Cimenti, Shun-wen Amy Yang, Liviu Catoiu
  • Publication number: 20180294500
    Abstract: A method is disclosed for improving the durability of membrane electrode assemblies in solid polymer electrolyte fuel cells by reducing the amount of halogen ion contaminants present. Silver carbonate is dissolved in an ionomer dispersion and incorporated into an appropriate component in the fuel cell where it reacts with halogen ion present to form silver halides. The component is then exposed to a suitable light source that decomposes the halide into halogen gas which is then removed prior to final assembly of the fuel cell.
    Type: Application
    Filed: March 21, 2018
    Publication date: October 11, 2018
    Inventors: Yunsong Yang, Yuquan Zou, Keping Wang, Carmen Chuy
  • Patent number: 9962521
    Abstract: Devices including a flexible substrate and a grafted polymer brush coating on at least one surface of the flexible substrate and methods for making and using such devices are provided herein. The grafted polymer brush included on the devices allow for controlled bending of the device during use.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: May 8, 2018
    Assignee: University of British Columbia
    Inventors: Jayachandran N. Kizhakkedathu, Yuquan Zou, A. Srikantha Phani, Donald E. Brooks
  • Publication number: 20170179497
    Abstract: Simplified methods for preparing a catalyst coated membrane (CCM) for solid polymer electrolyte fuel cells. The CCM has two reinforcing, expanded polymer sheets and the methods involve forming the electrolyte membrane from ionomer solution during assembly of the CCM. Thus, the conventional requirement to obtain, handle, and decal transfer solid polymer sheets in CCM preparation can be omitted. Further, CCM structures with improved mechanical strength can be prepared by orienting the expanded polymer sheets such that the stronger tensile strength direction of one is orthogonal to the other. Such improved CCM structures can be fabricated using the simplified methods.
    Type: Application
    Filed: December 12, 2016
    Publication date: June 22, 2017
    Inventors: Yuquan Zou, Owen Thomas, Scott McDermid, Yunsong Yang, Jing Li, Carmen Chuy
  • Publication number: 20170025699
    Abstract: Improved additives can be used to prepare polymer electrolyte for membrane electrode assemblies in polymer electrolyte fuel cells. Use of these improved additives can not only improve durability and performance, but can also provide a marked performance improvement during initial conditioning of the fuel cells. The additives are chemical complexes comprising certain metal and organic ligand components.
    Type: Application
    Filed: July 19, 2016
    Publication date: January 26, 2017
    Inventors: Keping Wang, Yunsong Yang, Carmen Chuy, Jing Li, Owen Thomas, Yuquan Zou
  • Patent number: 9102789
    Abstract: A proton conducting copolymer electrolyte with competitive voltage versus current density characteristics and superior durability comprises a proton conducting hydrophilic domain comprising a sulfonated poly(phenylene) polymer, and a hydrophobic domain comprising a main chain comprising a plurality of bonded arylene groups wherein essentially all of the bonds in the main chain of the copolymer are carbon-carbon or, to a certain extent, carbon-sulfone bonds. More particularly, none of the bonds in the chains of the copolymer are ether bonds. Due to the absence of ether bonds, the copolymer electrolyte is less susceptible to degradation in solid polymer fuel cells.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: August 11, 2015
    Assignees: Daimler AG, Ford Motor Company
    Inventors: Yunsong Yang, Yuquan Zou, Jing Li, Keping Wang
  • Publication number: 20130303981
    Abstract: Devices including a flexible substrate and a grafted polymer brush coating on at least one surface of the flexible substrate and methods for making and using such devices are provided herein. The grafted polymer brush included on the devices allow for controlled bending of the device during use.
    Type: Application
    Filed: February 3, 2012
    Publication date: November 14, 2013
    Applicant: UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Jayachandran N. Kizhakkedathu, Yuquan Zou, A. Srikantha Phani, Donald E. Brooks